Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Cecilia Viviana Alvarado"'
Autor:
Cecilia Viviana Alvarado, María Fernanda Rubio, Pablo Nicolas Fernández Larrosa, Laura Carolina Panelo, Pablo Javier Azurmendi, Marina Ruiz Grecco, Giselle Astrid Martínez-Nöel, Mónica Alejandra Costas
Publikováno v:
FEBS Open Bio, Vol 4, Iss C, Pp 450-457 (2014)
RAC3 is a coactivator of glucocorticoid receptor and nuclear factor-κB (NF-κB) that is usually over-expressed in tumors and which also has important functions in the immune system. We investigated the role of the inflammatory response in the contro
Externí odkaz:
https://doaj.org/article/1f0b0417a8c6465f853a0c3f31924b5a
Autor:
Elba Vazquez, Leonardo Paz, Laura Carolina Panelo, Mileni Soares Machado, Cecilia Viviana Alvarado, Alejandro J. Urtreger, Maria Fernanda Rubio, Felipe Martín Jaworski, Monica Alejandra Costas
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Oncotarget
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Oncotarget
RAC3 is a transcription coactivator, usually overexpressed in several tumors and required to maintain the pluripotency in normal stem cells. In this work we studied the association between RAC3 overexpression on cancer cell stemness and the capacity
Autor:
Giselle Astrid Martinez-Noel, Laura Panelo, Maria Fernanda Rubio, Marina Ruiz Grecco, Monica Alejandra Costas, Pablo Nicolas Fernandez Larrosa, Sabrina Micenmacher, Cecilia Viviana Alvarado
Publikováno v:
Cancer Sci
RAC3 is an oncogene naturally overexpressed in several tumors. Besides its role as coactivator, it can exert several protumoral cytoplasmic actions. Autophagy was found to act either as a tumor suppressor during the early stages of tumor development,
Autor:
Laura Carolina Panelo, Sabrina Mariel Micenmacher, Pablo N. Larrosa Fernandez, Maria Fernanda Rubio, Cecilia Viviana Alvarado, Marina Ruiz Grecco, Monica Alejandra Costas, Georgina Pamela Colo, Giselle M. A. Martínez-Noël
Publikováno v:
Biochimica et biophysica acta. 1823(6)
NF-κB regulates the expression of Cyclin D1 (CD1), while RAC3 is an NF-κB coactivator that enhances its transcriptional activity. In this work, we investigated the regulatory role of CD1 on NF-κB activity. We found that CD1 inhibits NF-κB transcr
Autor:
Monica Alejandra Costas, Georgina Pamela Colo, Victor E. Nahmod, Santiago E. Werbajh, Cecilia Viviana Alvarado, I M Nojek, Mario D. Galigniana, Maria Fernanda Rubio, Pablo Christian Echeverria
Publikováno v:
Oncogene. 27(17)
The p160 nuclear receptor coactivators represent a family of molecules, which are recruited by steroid nuclear receptors as well as other transcription factors that are over-expressed in several tumors. We investigated the role of one member of this
Autor:
Monica Alejandra Costas, M. Ruiz Grecco, D.L. Mengual Gomez, D F Alonso, Daniel E. Gomez, Laura Carolina Panelo, Maria Fernanda Rubio, Cecilia Viviana Alvarado, P. N. Fernández Larrosa
Publikováno v:
Cell Death & Disease
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Receptor-associated coactivator 3 (RAC3) is a nuclear receptor coactivator usually overexpressed in tumors that exerts oncogenicfunctions in the cytoplasm and the nucleus. Although as part of its oncogenic actions it was previously identified as an i
Autor:
Cristina Aguirre, Cecilia Viviana Alvarado, Laura Carolina Panelo, Maria Fernanda Rubio, P. N. Fernández Larrosa, Monica Alejandra Costas, M. Ruiz Grecco
Publikováno v:
Transplantation Journal. 94:762
Autor:
Cecilia Viviana Alvarado, Marina Ruiz Grecco, Pablo Nicolas Fernandez Larrosa, Monica Alejandra Costas, Laura Carolina Panelo, Maria Fernanda Rubio, Giselle M. A. Martínez-Noël, Pablo Javier Azurmendi
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
FEBS Open Bio
FEBS Open Bio, Vol 4, Iss C, Pp 450-457 (2014)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
FEBS Open Bio
FEBS Open Bio, Vol 4, Iss C, Pp 450-457 (2014)
Highlights • The inflammatory response increases the expression of RAC3 in vitro and in vivo. • TNF induces the increase of RAC3 at transcriptional level through NF-κB activation. • Glucocorticoids also induce the increase of RAC3 expression l