Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Cecilia Vitali"'
Autor:
Leonida Hehl, Kate T. Creasy, Cecilia Vitali, Eleonora Scorletti, Katharina S. Seeling, Mara S. Vell, Miriam D. Rendel, Donna Conlon, Regeneron Genetics Center, Marijana Vujkovic, Inuk Zandvakili, Christian Trautwein, Kai M. Schneider, Daniel J. Rader, Carolin V. Schneider
Publikováno v:
Hepatology Communications, Vol 8, Iss 5 (2024)
Background:. Common variants of the max-like protein X (MLX)-interacting protein-like (MLXIPL) gene, encoding the transcription factor carbohydrate-responsive element-binding protein, have been shown to be associated with plasma triglyceride levels.
Externí odkaz:
https://doaj.org/article/183435d2206a42fdbf55f5d2b4325b1c
Autor:
Donna M. Conlon, Siri Kanakala, Tess Cherlin, Yi-An Ko, Cecilia Vitali, Sharavana Gurunathan, Rasika Venkatesh, Jakob Woerner, Lindsay A. Guare, Penn Medicine Biobank, Anurag Verma, Shefali S. Verma, Marie A. Guerraty
Publikováno v:
Genes, Vol 15, Iss 8, p 1098 (2024)
Metabolic dysfunction-associated Fatty Liver Disease (MAFLD) has emerged as one of the leading cardiometabolic diseases. Friend of GATA2 (FOG2) is a transcriptional co-regulator that has been shown to regulate hepatic lipid metabolism and accumulatio
Externí odkaz:
https://doaj.org/article/8cd7f8509c7d4754bd06c03f28fe3d76
Autor:
Cecilia Vitali, Archna Bajaj, Christina Nguyen, Jill Schnall, Jinbo Chen, Kostas Stylianou, Daniel J. Rader, Marina Cuchel
Publikováno v:
Journal of Lipid Research, Vol 63, Iss 3, Pp 100169- (2022)
Syndromes associated with LCAT deficiency, a rare autosomal recessive condition, include fish-eye disease (FED) and familial LCAT deficiency (FLD). FLD is more severe and characterized by early and progressive chronic kidney disease (CKD). No treatme
Externí odkaz:
https://doaj.org/article/2ba2a876ac9c485281fe0017cc041977
Autor:
Sumeet A Khetarpal, Cecilia Vitali, Michael G Levin, Derek Klarin, Joseph Park, Akhil Pampana, John S Millar, Takashi Kuwano, Dhavamani Sugasini, Papasani V Subbaiah, Jeffrey T Billheimer, Pradeep Natarajan, Daniel J Rader
Publikováno v:
PLoS Genetics, Vol 17, Iss 9, p e1009802 (2021)
Triglyceride-rich lipoproteins (TRLs) are circulating reservoirs of fatty acids used as vital energy sources for peripheral tissues. Lipoprotein lipase (LPL) is a predominant enzyme mediating triglyceride (TG) lipolysis and TRL clearance to provide f
Externí odkaz:
https://doaj.org/article/8f70a22c3e124be3bfe8597898cbddf1
Autor:
Gualtiero I. Colombo, Vanessa Bianconi, Alice Bonomi, Sara Simonelli, Mauro Amato, Beatrice Frigerio, Alessio Ravani, Cecilia Vitali, Daniela Sansaro, Daniela Coggi, Massimo R. Mannarino, Kai P. Savonen, Sudhir Kurl, Bruna Gigante, Andries J. Smit, Philippe Giral, Elena Tremoli, Laura Calabresi, Fabrizio Veglia, Matteo Pirro, Damiano Baldassarre, on behalf of the IMPROVE Study Group
Publikováno v:
Biomedicines, Vol 9, Iss 3, p 286 (2021)
The impact of cholesteryl ester transfer protein (CETP) on atherosclerosis is highly debated. This study aimed to investigate the associations between plasma CETP or CETP genotypes and carotid intima-media thickness (cIMT) and the influence of high-d
Externí odkaz:
https://doaj.org/article/a4f3cdccf3ab4a1aa625d0f6d2216bab
Autor:
Alice Ossoli, Edward B Neufeld, Seth G Thacker, Boris Vaisman, Milton Pryor, Lita A Freeman, Christine A Brantner, Irina Baranova, Nicolás O Francone, Stephen J Demosky, Cecilia Vitali, Monica Locatelli, Mauro Abbate, Carlamaria Zoja, Guido Franceschini, Laura Calabresi, Alan T Remaley
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0150083 (2016)
Human familial lecithin:cholesterol acyltransferase (LCAT) deficiency (FLD) is characterized by low HDL, accumulation of an abnormal cholesterol-rich multilamellar particle called lipoprotein-X (LpX) in plasma, and renal disease. The aim of our study
Externí odkaz:
https://doaj.org/article/924d5b398dcb4f228c32af616b5ce081
Publikováno v:
Circulation. 146:740-742
Publikováno v:
Current opinion in lipidology.
Genetic lecithin:cholesterol acyltransferase (LCAT) deficiency is a rare, inherited, recessive disease, which manifests as two different syndromes: Familial LCAT deficiency (FLD) and Fish-eye disease (FED), characterized by low HDL-C and corneal opac
Autor:
Robert S Rosenson, Poulabi Banerjee, Claudia Gonzaga-Jauregui, Jennifer McGinniss, Cecilia Vitali, Robert Pordy, Jian Zhao, Manish P Ponda, Daniel J Rader
Publikováno v:
Circulation. 144
Background: Hypertriglyceridemia (HTG) is the consequence of elevated triglyceride-rich lipoproteins (TGRLs) containing apolipoprotein B (apoB), such as VLDL and chylomicrons. Epidemiological and genetic studies indicate that triglycerides (TGs) and
Autor:
Sylvia Stankov, Cecilia Vitali, Joseph Park, David Nguyen, S. Walter Englander, Michael C Phillips, Nicholas J Hand, Daniel J Rader
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 41
Plasma triglycerides (TGs) are an independent predictor of the risk for CAD, the leading cause of death worldwide. TGs are also positively associated with risk and severity of hyperTG-induced acute pancreatitis (HTG-AP). Current therapies are often i