ProNGF\NGF imbalance triggers learning and memory deficits, neurodegeneration and spontaneous epileptic-like discharges in transgenic mice

Autor: Rossella Brandi, Sonia Piccinin, Luisa Fasulo, Raffaella Scardigli, Simona Capsoni, Antonino Cattaneo, Francesca Malerba, Gianluca Amato, Annalisa Manca, Fulvio Florenzano, Giovanni Meli, Francesca Paoletti, P Capelli, Robert Nisticò, Sara Marinelli, F La Regina, Cecilia Tiveron, Agnese Lecci, Nicola Berretta, Flaminia Pavone, L. Pistillo, Simona D'Aguanno

Publikováno v: Cell death and differentiation (Online) Epub ahead of print (2013). doi:10.1038/cdd.2013.22
info:cnr-pdr/source/autori:Tiveron C, Fasulo L, Capsoni S, Malerba F, Marinelli S, Paoletti F, Piccinin S, Scardigli R, Amato G, Brandi R, Capelli P, D'Aguanno S, Florenzano F, La Regina F, Lecci A, Manca A, Meli G, Pistillo L, Berretta N, Nisticò R, Pavone F, Cattaneo A./titolo:ProNGF\NGF imbalance triggers learning and memory deficits, neurodegeneration and spontaneous epileptic-like discharges in transgenic mice/doi:10.1038%2Fcdd.2013.22/rivista:Cell death and differentiation (Online)/anno:2013/pagina_da:/pagina_a:/intervallo_pagine:/volume:Epub ahead of

ProNGF, the precursor of mature nerve growth factor (NGF), is the most abundant form of NGF in the brain. ProNGF and mature NGF differ significantly in their receptor interaction properties and in their bioactivity. ProNGF increases markedly in the c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db8962d5aff9056e6eb8f28866941d2f
https://doi.org/10.1038/cdd.2013.22

Role of the Molybdoflavoenzyme Aldehyde Oxidase Homolog 2 in the Biosynthesis of Retinoic Acid: Generation and Characterization of a Knockout Mouse

Autor: Antonio Bastone, Mineko Terao, Maddalena Fratelli, Eugenio Scanziani, Enrico Garattini, Cecilia Tiveron, Alessandra Mancuso, Mami Kurosaki, Renzo Bagnati, Chiara Giudice, Maria Monica Barzago

Publikováno v: Molecular and Cellular Biology. 29:357-377

The mouse aldehyde oxidase AOH2 (aldehyde oxidase homolog 2) is a molybdoflavoenzyme. Harderian glands are the richest source of AOH2, although the protein is detectable also in sebaceous glands, epidermis, and other keratinized epithelia. The levels

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7727df864d10579f210aedeada2f2ff3
https://doi.org/10.1128/mcb.01385-08

Increased Ca2+ storage capacity of the skeletal muscle sarcoplasmic reticulum of transgenic mice over-expressing membrane bound calcium binding protein junctate

Autor: Feliciano Protasi, Cecilia Paolini, C. Huchet-Cadiou, Cristiano Grasso, Alexandra Divet, Susan Treves, Francesco Zorzato, Silvia Paesante, Dario Cavagna, Cecilia Tiveron

Publikováno v: Journal of Cellular Physiology. 213:464-474

Junctate is an integral sarco(endo)plasmic reticulum protein expressed in many tissues including heart and skeletal muscle. Because of its localization and biochemical characteristics, junctate is deemed to participate in the regulation of the intrac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e79a97bbada1338b8b097c9c8938d23b
https://doi.org/10.1002/jcp.21121

Deletion of the mental retardation gene Gdi1 impairs associative memory and alters social behavior in mice

Autor: Chiara Leoni, Cecilia Tiveron, Hans Welzl, Hans-Peter Lipp, Daniela Toniolo, Laura Pozzi, Flavia Valtorta, Andrea Menegon, Paul F. Chapman, Marina Raffaele di Barletta, Mark F. Ramsay, Stavros Papadimitriou, Simon G. Knevett, Patrizia D'Adamo, Laura Tatangelo, David P. Wolfer

Publikováno v: Scopus-Elsevier

Non-specific mental retardation (NSMR) is a common human disorder characterized by mental handicap as the only clinical symptom. Among the recently identified MR genes is GDI1, which encodes alpha Gdi, one of the proteins controlling the activity of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b763c5e2544ccaac77d77b8b3ec8714
https://doi.org/10.1093/hmg/11.21.2567

Flow cytometric assessment of trophosphamide toxicity on mouse spermatogenesis

Autor: Cecilia Bartoleschi, Marcello Spanò, Francesca Pacchierotti, Cecilia Tiveron, Giorgio Leter, Eugenia Cordelli

Publikováno v: Cytometry. 24:174-180

The effects of trophosphamide on mouse reproductive cells have been investigated by flow cytometric analysis of testicular cell populations and alterations of sperm chromatin structure. Mice were treated with single intraperitoneal injections of TP,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c14516308c3899374c767d884753d682
https://doi.org/10.1002/(sici)1097-0320(19960601)24:2<174::aid-cyto10>3.0.co