Zobrazeno 1 - 10
of 199
pro vyhledávání: '"Cecilia M. Giachelli"'
Autor:
Alexander Blümke, Erica Ijeoma, Jessica Simon, Rachel Wellington, Medania Purwaningrum, Sergei Doulatov, Elizabeth Leber, Marta Scatena, Cecilia M. Giachelli
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Background Ever since their discovery, induced pluripotent stem cells (iPSCs) have been extensively differentiated into a large variety of cell types. However, a limited amount of work has been dedicated to differentiating iPSCs into osteocl
Externí odkaz:
https://doaj.org/article/9df3251ee8e841f28953b0c6134f91cf
Autor:
Medania Purwaningrum, Cecilia M. Giachelli, Thanaphum Osathanon, Sirirat Rattanapuchpong, Chenphop Sawangmake
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-19 (2023)
Abstract Periodontal ligament stem cells (PDLSCs) play a significant role on periodontal tissue and alveolar bone homeostasis. During inflammation, interleukin (IL)-6 serves as one of key cytokine players controlling tissue reaction as well as alveol
Externí odkaz:
https://doaj.org/article/6271ebbc81c5490b8f59c49d585e2c38
Autor:
Isabella Jennings, Hao Zhou, Suryo Kuncorojakti, Medania Purwaningrum, Marta Scatena, Cecilia M. Giachelli
Publikováno v:
Journal of Clinical and Translational Science, Vol 8, Pp 104-104 (2024)
OBJECTIVES/GOALS: The global incidence of calcific aortic valve disease (CAVD) increased 3.5-fold since 1990. No preventative or therapeutic pharmaceutical therapies exist for CAVD. We will establish the therapeutic potential of osteoclast-derived ex
Externí odkaz:
https://doaj.org/article/3255137a6d1f41c3aac5d9e1beb9a892
Autor:
Subramanian Dharmarajan, Mei Y. Speer, Kate Pierce, Jake Lally, Elizabeth M. Leaf, Mu-En Lin, Marta Scatena, Cecilia M. Giachelli
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Background: Calcific aortic valve disease is common in the aging population and is characterized by the histological changes of the aortic valves including extracellular matrix remodeling, osteochondrogenic differentiation, and calcification. Combine
Externí odkaz:
https://doaj.org/article/3bbcae9c41154eefb33daa442b24a944
Autor:
Sampada Chande, Caroline Zeiss, Joëlle Vézier, Nicholas W. Chavkin, Nati Hernando, Cecilia M. Giachelli, Carsten A. Wagner, Laurent Beck, Sarah Beck-Cormier, Clemens Bergwitz
Publikováno v:
Bone Reports, Vol 13, Iss , Pp 100648- (2020)
Externí odkaz:
https://doaj.org/article/f4abdf1d68ec45d6a26fd32eb2dbb6b5
Publikováno v:
Stem Cell Reports, Vol 2, Iss 3, Pp 271-281 (2014)
For cell-based treatments of myocardial infarction, a better understanding of key developmental signaling pathways and more robust techniques for producing cardiomyocytes are required. Manipulation of Notch signaling has promise as it plays an import
Externí odkaz:
https://doaj.org/article/13ea277b502444e0bf6456ca1f921c8a
Autor:
Marta Scatena, Jake Lally, Cecilia M. Giachelli, Mu-En Lin, Elizabeth M. Leaf, Mei Y. Speer, Subramanian Dharmarajan, Kate Pierce
Publikováno v:
Frontiers in Cardiovascular Medicine
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Background: Calcific aortic valve disease is common in the aging population and is characterized by the histological changes of the aortic valves including extracellular matrix remodeling, osteochondrogenic differentiation, and calcification. Combine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48a30baf0cae75bf3a5b203b6789683e
Autor:
Mary C. Wallingford, Elizabeth M. Leaf, Cecilia M. Giachelli, Susan M Lund, Kadin E Brooks, Nicholas W. Chavkin
Publikováno v:
J Vasc Res
The sodium-dependent phosphate transporter, SLC20A1, is required for elevated inorganic phosphate (Pi) induced vascular smooth muscle cell (VSMC) matrix mineralization and phenotype transdifferentiation. Recently, elevated Pi was shown to induce ERK1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::089163902302f3f7fc36a4e509310c74
https://pubmed.ncbi.nlm.nih.gov/33951626
https://pubmed.ncbi.nlm.nih.gov/33951626
Autor:
Cameron W Rementer, Meiting Wu, Worakanya Buranaphatthana, Hsueh-Ying L Yang, Marta Scatena, Cecilia M Giachelli
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e84465 (2013)
Osteoclasts are bone-resorbing cells that are critical for the normal formation and maintenance of teeth and skeleton. Osteoclast deficiency can contribute to heterotopic ossification (HO), a pathology that is particularly detrimental to the mechanic
Externí odkaz:
https://doaj.org/article/c1b8c2db062943978399f49e1fe12605
Autor:
Juan Serna, Nicholas W. Chavkin, Gerald I. Shulman, Carsten A. Wagner, Michael J. Jurczak, Sampada Chande, Daniel Caballero, Caroline J. Zeiss, Bryan B. Ho, Dominik Pesta, Cecilia M. Giachelli, Jonathan Fetene, Ali Nasiri, Clemens Bergwitz, Nati Hernando
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Low blood phosphate (Pi) reduces muscle function in hypophosphatemic disorders. Which Pi transporters are required and whether hormonal changes due to hypophosphatemia contribute to muscle function is unknown. To address these questions we generated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cbf5d3d5679123ea7b9868c240aed53
http://europepmc.org/articles/PMC7033257
http://europepmc.org/articles/PMC7033257