Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Cecilia M. Culp"'
Autor:
Jared T. Ahrendsen, Wendy B. Macklin, Jennifer N. Bourne, Lisbet T. Finseth, Sean P. Hickey, Cecilia M. Culp, Elizabeth Gould, Danielle E. Harlow
Publikováno v:
The Journal of Neuroscience. 38:787-802
Shp2 is a nonreceptor protein tyrosine phosphatase that has been shown to influence neurogenesis, oligodendrogenesis, and oligodendrocyte differentiation. Furthermore, Shp2 is a known regulator of the Akt/mammalian target of rapamycin and ERK signali
Autor:
Elizabeth A. Gould, Paco S. Herson, Sean P. Hickey, Himmat Grewal, Frank Strnad, Jared T. Ahrendsen, Cecilia M. Culp, Takeru Shimizu, Wendy B. Macklin, Richard J. Traystman
Publikováno v:
Glia. 64:1972-1986
White matter injury following ischemic stroke is a major cause of functional disability. Injury to both myelinated axons and oligodendrocytes, the myelin producing cells in the central nervous system, occurs in experimental models of ischemic stroke.
Publikováno v:
The Journal of Neuroscience. 34:1333-1343
Plp1gene expression occurs very early in development, well before the onset of myelination, creating a conundrum with regard to the function of myelin proteolipid protein (PLP), one of the major proteins in compact myelin. Using PLP-EGFP mice to inve