Zobrazeno 1 - 10
of 340
pro vyhledávání: '"Cecilia Lo"'
Autor:
Peter J. Eggenhuizen, Rachel M. Y. Cheong, Cecilia Lo, Janet Chang, Boaz H. Ng, Yi Tian Ting, Julie A. Monk, Khai L. Loh, Ashraf Broury, Elean S. V. Tay, Chanjuan Shen, Yong Zhong, Steven Lim, Jia Xi Chung, Rangi Kandane-Rathnayake, Rachel Koelmeyer, Alberta Hoi, Ashutosh Chaudhry, Paolo Manzanillo, Sarah L. Snelgrove, Eric F. Morand, Joshua D. Ooi
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Antigen-specific regulatory T cells (Tregs) suppress pathogenic autoreactivity and are potential therapeutic candidates for autoimmune diseases such as systemic lupus erythematosus (SLE). Lupus nephritis is associated with autoreactivity to
Externí odkaz:
https://doaj.org/article/8948013d714c4e8e98c3470282119cef
Autor:
Quynh Nhu Dinh, Cecilia Lo, David Wong Zhang, Vivian Tran, Tayla Gibson-Hughes, Ashleigh Sheriff, Henry Diep, Hyun Ah Kim, Shenpeng R. Zhang, Liz J. Barreto-Arce, Maria Jelinic, Antony Vinh, Thiruma V. Arumugam, Siow Teng Chan, Rebecca Lim, Grant R. Drummond, Christopher G. Sobey, T. Michael De Silva
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Vascular inflammation and fibrosis are hallmarks of hypertension and contribute to the development of cardiovascular disease and cognitive impairment. However, current anti-hypertensive drugs do not treat the underlying tissue damage, such a
Externí odkaz:
https://doaj.org/article/c612cfe46001495bb86c12c472d59be3
Autor:
Timothy J Mead, Daniel R Martin, Lauren W Wang, Stuart A Cain, Cagri Gulec, Elisabeth Cahill, Joseph Mauch, Dieter Reinhardt, Cecilia Lo, Clair Baldock, Suneel S Apte
Publikováno v:
eLife, Vol 11 (2022)
The embryonic extracellular matrix (ECM) undergoes transition to mature ECM as development progresses, yet few mechanisms ensuring ECM proteostasis during this period are known. Fibrillin microfibrils are macromolecular ECM complexes serving structur
Externí odkaz:
https://doaj.org/article/5a97c8b12bf54934ac67208635fbd524
Autor:
Juhoon So, Mylarappa Ningappa, Joseph Glessner, Jun Min, Chethan Ashokkumar, Sarangarajan Ranganathan, Brandon W. Higgs, Dong Li, Qing Sun, Lori Schmitt, Amy C. Biery, Steven Dobrowolski, Christine Trautz, Leah Fuhrman, Molly Christine Schwartz, Nikolai Thomas Klena, Joseph Fusco, Krishna Prasadan, Morayooluwa Adenuga, Nada Mohamed, Qi Yan, Wei Chen, William Horne, Anil Dhawan, Khalid Sharif, Deirdre Kelly, Robert H Squires, George K. Gittes, Hakon Hakonarson, Victor Morell, Cecilia Lo, Shankar Subramaniam, Donghun Shin, Rakesh Sindhi
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Background/AimsInfectious and genetic factors are invoked, respectively in isolated biliary atresia (BA), or syndromic BA, with major extrahepatic anomalies. However, isolated BA is also associated with minor extrahepatic gut and cardiovascular anoma
Externí odkaz:
https://doaj.org/article/e1c329030930403a8e3a5542aa7c32a8
Autor:
Richard Francis, Xin Xu, Hyunsoo Park, Chin-Jen Wei, Stephen Chang, Bishwanath Chatterjee, Cecilia Lo
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26379 (2011)
Knockout mice deficient in the gap junction gene connexin43 exhibit developmental anomalies associated with abnormal neural crest, primordial germ cell, and proepicardial cell migration. These migration defects are due to a loss of directional cell m
Externí odkaz:
https://doaj.org/article/d128f399a19847008f7133a88769ac36
Autor:
Ricardo A. DeMoya, Rachel E. Forman-Rubinsky, Deon Fontaine, Joseph Shin, Simon C. Watkins, Cecilia Lo, Michael Tsang
Publikováno v:
bioRxiv
Hypoplastic left heart syndrome (HLHS) is a congenital heart disease where the left ventricle is reduced in size. A forward genetic screen in mice identified SIN3A associated protein 130kDa (Sap130), a protein in the chromatin modifying SIN3A/HDAC1 c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ea3f314e3e655e6f5a888235c89e8d1
https://doi.org/10.1101/2023.03.30.534737
https://doi.org/10.1101/2023.03.30.534737
Autor:
Paola Corti, Elizabeth Rochon, Jianmin Xue, Manush Saydmohammed, Caroline Smith, Maliha Zahid, Anthony DeMartino, Cecilia Lo, Michael Tsang, Jesus Tejero, Mark Gladwin
Cytoglobin is a highly conserved redox sensor heme protein with unknown physiological function. Unexpectedly, genetic deletion of zebrafish cytoglobin (cygb2) causes cardiac and gastro-intestinal tract laterality defects, modeling Kartagener’s synd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89817605622517210473193eb98ced97
https://doi.org/10.21203/rs.3.rs-2132286/v1
https://doi.org/10.21203/rs.3.rs-2132286/v1
Autor:
Angelo B. Arrigo, Wenjuan Zhu, Kylia A. Williams, Carla Guzman-Moreno, Cecilia Lo, Jiuann-Huey I. Lin
Publikováno v:
Genes. 14:947
Due to the prevalence of congenital heart disease in the human population, determining the role of variants in congenital heart disease (CHD) can give a better understanding of the cause of the disorder. A homozygous missense mutation in the LDL rece
Autor:
Jean Richa, Cecilia Lo
Publikováno v:
Transgenic Animals ISBN: 9781003211099
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70066c7fcfd98b7890935d3c1f4b930c
https://doi.org/10.1201/9781003211099-58
https://doi.org/10.1201/9781003211099-58
Autor:
Timothy J Mead, Daniel R Martin, Lauren W Wang, Stuart A Cain, Cagri Gulec, Elisabeth Cahill, Joseph Mauch, Dieter Reinhardt, Cecilia Lo, Clair Baldock, Suneel S Apte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f43e3964aa0b48a62f53a263799cf48b
https://doi.org/10.7554/elife.71142.sa2
https://doi.org/10.7554/elife.71142.sa2