Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Cecilia Laterza"'
Autor:
Francesco Panariello, Onelia Gagliano, Camilla Luni, Antonio Grimaldi, Silvia Angiolillo, Wei Qin, Anna Manfredi, Patrizia Annunziata, Shaked Slovin, Lorenzo Vaccaro, Sara Riccardo, Valentina Bouche, Manuela Dionisi, Marcello Salvi, Sebastian Martewicz, Manli Hu, Meihua Cui, Hannah Stuart, Cecilia Laterza, Giacomo Baruzzo, Geoffrey Schiebinger, Barbara Di Camillo, Davide Cacchiarelli, Nicola Elvassore
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Human cellular reprogramming to induced pluripotency is still an inefficient process, which has hindered studying the role of critical intermediate stages. Here we take advantage of high efficiency reprogramming in microfluidics and temporal
Externí odkaz:
https://doaj.org/article/4881a0e99d974abc86ba20b6cd9be0ad
Autor:
Flora Tassone, Dragana Protic, Emily Graves Allen, Alison D. Archibald, Anna Baud, Ted W. Brown, Dejan B. Budimirovic, Jonathan Cohen, Brett Dufour, Rachel Eiges, Nicola Elvassore, Lidia V. Gabis, Samantha J. Grudzien, Deborah A. Hall, David Hessl, Abigail Hogan, Jessica Ezzell Hunter, Peng Jin, Poonnada Jiraanont, Jessica Klusek, R. Frank Kooy, Claudine M. Kraan, Cecilia Laterza, Andrea Lee, Karen Lipworth, Molly Losh, Danuta Loesch, Reymundo Lozano, Marsha R. Mailick, Apostolos Manolopoulos, Veronica Martinez-Cerdeno, Yingratana McLennan, Robert M. Miller, Federica Alice Maria Montanaro, Matthew W. Mosconi, Sarah Nelson Potter, Melissa Raspa, Susan M. Rivera, Katharine Shelly, Peter K. Todd, Katarzyna Tutak, Jun Yi Wang, Anne Wheeler, Tri Indah Winarni, Marwa Zafarullah, Randi J. Hagerman
Publikováno v:
Cells, Vol 12, Iss 18, p 2330 (2023)
The premutation of the fragile X messenger ribonucleoprotein 1 (FMR1) gene is characterized by an expansion of the CGG trinucleotide repeats (55 to 200 CGGs) in the 5’ untranslated region and increased levels of FMR1 mRNA. Molecular mechanisms lead
Externí odkaz:
https://doaj.org/article/a0b6f75a833d4184b35d72147f86dffc
Autor:
Giovanni Giuseppe Giobbe, Francesco Bonfante, Brendan C. Jones, Onelia Gagliano, Camilla Luni, Elisa Zambaiti, Silvia Perin, Cecilia Laterza, Georg Busslinger, Hannah Stuart, Matteo Pagliari, Alessio Bortolami, Eva Mazzetto, Anna Manfredi, Chiara Colantuono, Lucio Di Filippo, Alessandro Filippo Pellegata, Valentina Panzarin, Nikhil Thapar, Vivian Sze Wing Li, Simon Eaton, Davide Cacchiarelli, Hans Clevers, Nicola Elvassore, Paolo De Coppi
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Several clinical reports have described gastrointestinal symptoms for COVID-19, though whether the virus can replicate within the stomach remains unclear. Here the authors generate gastric organoids from human biopsies and show that the virus can eff
Externí odkaz:
https://doaj.org/article/16f8748d432646d085ed25fa4b80e5ce
Autor:
Yang Yang, Cecilia Laterza, Hannah T. Stuart, Federica Michielin, Onelia Gagliano, Anna Urciuolo, Nicola Elvassore
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
The human developmental processes during the early post-implantation stage instruct the specification and organization of the lineage progenitors into a body plan. These processes, which include patterning, cell sorting, and establishment of the thre
Externí odkaz:
https://doaj.org/article/c64b3654a93a47d58fbfc7fe788c5d71
Autor:
Marita Grønning Hansen, Cecilia Laterza, Sara Palma‐Tortosa, Giedre Kvist, Emanuela Monni, Oleg Tsupykov, Daniel Tornero, Naomi Uoshima, Jordi Soriano, Johan Bengzon, Gianvito Martino, Galyna Skibo, Olle Lindvall, Zaal Kokaia
Publikováno v:
Stem Cells Translational Medicine, Vol 9, Iss 11, Pp 1365-1377 (2020)
Abstract Several neurodegenerative diseases cause loss of cortical neurons, leading to sensory, motor, and cognitive impairments. Studies in different animal models have raised the possibility that transplantation of human cortical neuronal progenito
Externí odkaz:
https://doaj.org/article/181e28f31b85430e89ba814c4933f424
Autor:
Anna Maria Tolomeo, Cecilia Laterza, Eleonora Grespan, Federica Michielin, Isaac Canals, Zaal Kokaia, Maurizio Muraca, Onelia Gagliano, Nicola Elvassore
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Recent advancements in cell engineering have succeeded in manipulating cell identity with the targeted overexpression of specific cell fate determining transcription factors in a process named transcriptional programming. Neurogenin2 (NGN2) is suffic
Externí odkaz:
https://doaj.org/article/70fb9a7e10ef467b87f3bb33ca6e744c
Autor:
Ruimin Ge, Daniel Tornero, Masao Hirota, Emanuela Monni, Cecilia Laterza, Olle Lindvall, Zaal Kokaia
Publikováno v:
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-15 (2017)
Abstract Background Choroid plexus (CP) supports the entry of monocyte-derived macrophages (MDMs) to the central nervous system in animal models of traumatic brain injury, spinal cord injury, and Alzheimer’s disease. Whether the CP is involved in t
Externí odkaz:
https://doaj.org/article/1e7aac8b30324376bc069258443c6ee3
Autor:
Petter Säwen, Mohamed Eldeeb, Eva Erlandsson, Trine A Kristiansen, Cecilia Laterza, Zaal Kokaia, Göran Karlsson, Joan Yuan, Shamit Soneji, Pankaj K Mandal, Derrick J Rossi, David Bryder
Publikováno v:
eLife, Vol 7 (2018)
A hallmark of adult hematopoiesis is the continuous replacement of blood cells with limited lifespans. While active hematopoietic stem cell (HSC) contribution to multilineage hematopoiesis is the foundation of clinical HSC transplantation, recent rep
Externí odkaz:
https://doaj.org/article/c65d59c4c6b34c25b69c383fd329544e
Autor:
Cecilia Laterza, Naomi Uoshima, Daniel Tornero, Ulrika Wilhelmsson, Anna Stokowska, Ruimin Ge, Milos Pekny, Olle Lindvall, Zaal Kokaia
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192118 (2018)
Induced pluripotent stem cells (iPSCs) or their progeny, derived from human somatic cells, can give rise to functional improvements after intracerebral transplantation in animal models of stroke. Previous studies have indicated that reactive gliosis,
Externí odkaz:
https://doaj.org/article/4a217fc114fc48c79494cc7dbee0ba28
Autor:
Francesca Sensi, Edoardo D'angelo, Andrea Biccari, Asia Marangio, Giulia Battisti, Sara Crotti, Matteo Fassan, Cecilia Laterza, Monica Giomo, Nicola Elvassore, Gaya Spolverato, Salvatore Pucciarelli, Marco Agostini
Publikováno v:
Translational Research. 253:57-67
Pancreatic cancer is likely to become one of the leading causes of cancer-related death in many countries within the next decade. Surgery is the potentially curative treatment for pancreatic ductal adenocarcinoma (PDAC), although only 10%-20% of pati