Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Cecilia Kwong"'
Autor:
Timothy P. Padera, Ethel R. Pereira, Hengbo Zhou, Rohin Banerji, Sue Zhang, Victoria Xiao, Zixiong Wang, Hadi Tavakoli Nia, Jan Willem Maurits van Wijnbergen, Ivy X. Chen, Peigen Huang, Cecilia Kwong, Dennis Jones, Benjamin J. Vakoc, Pin-Ji Lei
Publikováno v:
Nat Biomed Eng
Strong and durable anticancer immune responses are associated with the generation of activated cancer-specific T cells in the draining lymph nodes. However, cancer cells can colonize lymph nodes and drive tumour progression. Here, we show that lympho
Autor:
Dennis Jones, Zixiong Wang, Ivy Chen, Sue Zhang, Rohin Banerji, Pin‐Ji Lei, Hengbo Zhou, Victoria Xiao, Cecilia Kwong, Jan W. Van Wijnbergen, Ethel Pereira, Benjamin Vakoc, Peigen Huang, Hadi Nia, Timothy Padera
Publikováno v:
The FASEB Journal. 36
Autor:
Julie Donaghey, Cecilia Kwong, Allison Powell, Troy Patterson, Ella Liberzon, Richard Decker, Julio Gomez Rodriguez, Darby Kreienberg, Jennifer Bian, Urmi Patankar, Holly Horton, Jian Ding, Robert Hofmeister, Dario Gutierrez, Robert Tighe
Publikováno v:
Cancer Research. 82:557-557
We have previously described the generation of autologous T Cell Receptor Fusion Construct (TRuC™) T cells which are engineered to express a fusion protein comprised of an antibody-derived binder tethered to the extracellular domain of the CD3ε si
Autor:
Jennifer S. Lee, Agnieszka Denslow, Brian B. Haines, Christophe Quéva, Michael Ball, Lorenz Ponce, Caroline Webb, Jacqueline Gursha, Daniel Wambua, Cecilia Kwong, Finer Mitchell H, Michael Paglia, Prajna Behera, Judith Jacques, Lorena Lerner, Allison Colthart, Lingxin Kong, Peter Grzesik, Terry Farkaly, Laura Viggiano Salta, Edward M. Kennedy, Caity Montagna
Publikováno v:
Cancer Immunology Research. 8:B23-B23
Although oncolytic viruses have shown clinical efficacy for local treatment of cancerous tumors, the ability to induce immune-mediated regression to visceral lesions is not robust. Immune checkpoint modulation has been efficacious in a fraction of ca
Autor:
Peter Grzesik, Caitlin Goshert, Prajna Behera, Jennifer S. Lee, Brian B. Haines, Cecilia Kwong, Allison Colthart, Lingxin Kong, Michael Ball, Terry Farkaly, Jacqueline Gursha, Christophe Quéva, Edward M. Kennedy, Agnieszka Denslow, Daniel Wambua, Lorena Lerner
Publikováno v:
Cancer Research. 79:940-940
ONCR-177 is a highly modified recombinant oncolytic Herpes Simplex Virus (oHSV) designed to be a safe and efficacious therapy for the treatment of solid tumor indications. Complementary safety mechanisms, such as tissue-specific miR attenuation of es
Autor:
Agnieszka Denslow, Brian B. Haines, Michael S. Ball, Jacqueline Gursha, Daniel Wambua, Cecilia Kwong, Lingxin Kong, Allison Colthart, Prajna Behera, Peter Grzesik, Jennifer Lee, Terry Farkaly, Caitlin Goshert, Edward M. Kennedy, Lorena Lerner, Christophe Quéva
Publikováno v:
Cancer Research. 79:1452-1452
Oncolytic viruses, through cancer cell-selective lysis and accompanying release of danger signals that promote immune activation, have demonstrated antitumor efficacy in monotherapy of metastatic melanoma and have shown promising activity in combinat
Autor:
Weiguo Yao, Alexandra Hicks, Jacqueline Gursha, Michael Paglia, Lorenz Ponce, Jingzang Miu, Terry Farkaly, Joseph C. Glorioso, Daniel Wambua, Christophe Quéva, Michael Ball, Cecilia Kwong, Finer Mitchell H, Kyle Grant, Paola Grandi, Laura Viggiano Salta
Publikováno v:
Cancer Research. 78:4698-4698
Glioblastoma multiforme (GBM) is a highly aggressive brain tumor associated with poor prognosis and resistance to current therapies. ONCR-1 is a novel oncolytic herpes simplex virus type-1 vector in development for the treatment of GBM. ONCR-1 utiliz
Autor:
John C. Gill, Ursula B. Kaiser, Shuyun Xu, Cecilia Martin, Cecilia Kwong, Víctor M. Navarro, Rona S. Carroll, Donald K. Clifton, Sekoni D. Noel, Robert A. Steiner
Publikováno v:
Endocrinology. 153(10)
At puberty, neurokinin B (NKB) and kisspeptin (Kiss1) may help to amplify GnRH secretion, but their precise roles remain ambiguous. We tested the hypothesis that NKB and Kiss1 are induced as a function of pubertal development, independently of the pr