Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Cecilia Koble"'
Autor:
Andrew Maynard, Renae M. Crosby, Byron Ellis, Robert Hamatake, Zhi Hong, Brian A. Johns, Kirsten M. Kahler, Cecilia Koble, Anna Leivers, Martin R. Leivers, Amanda Mathis, Andrew J. Peat, Jeffrey J. Pouliot, Christopher D. Roberts, Vicente Samano, Rachel M. Schmidt, Gary K. Smith, Andrew Spaltenstein, Eugene L. Stewart, Pia Thommes, Elizabeth M. Turner, Christian Voitenleitner, Jill T. Walker, Greg Waitt, Jason Weatherhead, Kurt Weaver, Shawn Williams, Lois Wright, Zhiping Z. Xiong, David Haigh, J. Brad Shotwell
Publikováno v:
Journal of Medicinal Chemistry. 57:1902-1913
A boronic acid moiety was found to be a critical pharmacophore for enhanced in vitro potency against wild-type hepatitis C replicons and known clinical polymorphic and resistant HCV mutant replicons. The synthesis, optimization, and structure-activit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6ce7599d644e69b47104c8ac1a7db2e
https://doi.org/10.1021/jm400317w
https://doi.org/10.1021/jm400317w
Publikováno v:
Journal of pharmaceutical sciences. 74(6)
Cis- and trans-4-n-Propyloctahydrobenzo(f)quinolines 4a,b were prepared for further assessment of dopaminergic effects of non-oxygenated dopamine congeners. The trans isomer 4b exhibited marked dopamine-like effects in the cat cardioaccelerator nerve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d51adc956b5c6ebad8fa390d94e35682
https://pubmed.ncbi.nlm.nih.gov/4040568
https://pubmed.ncbi.nlm.nih.gov/4040568
Publikováno v:
Chemischer Informationsdienst. 16
cis- and trans-4-n-Propyloctahydrobenzo(f)quinolines 4a,b were prepared for further assessment of dopaminergic effects of non-oxygenated dopamine congeners. The trans isomer 4b exhibited marked dopamine-like effects in the cat cardioaccelerator nerve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af999685cef0448cecdfa356009ce350
https://doi.org/10.1002/chin.198548207
https://doi.org/10.1002/chin.198548207