Development of sustainable synthesis of glucuronic acid glycodendrimers using ball milling and microwave-assisted CuAAC reaction

Autor: Cecilia García-Oliva, Alejandro Merchán, Almudena Perona, Pilar Hoyos, Ángel Rumbero, María J. Hernáiz

Publikováno v: New Journal of Chemistry. 46:6389-6393

Two green strategies for CuAAC reaction based on two activation pathways, solvent free mechanochemistry and microwave irradiation using a recycable biosolvent, are reported for the synthesis of glucuronic acid glycodendrimers with good conversión.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8cc4da1c32e343deb64b8d600e63da40
https://doi.org/10.1039/d1nj06132a

Enzymatic synthesis and molecular modelling studies of rhamnose esters using lipase from Pseudomonas stutzeri

Autor: Cecilia García-Oliva, Almudena Perona, Ángel Rumbero, Pilar Hoyos, María J. Hernáiz

Publikováno v: International Journal of Molecular Sciences; Volume 23; Issue 4; Pages: 2239

Rhamnolipids are becoming an important class of glycolipid biosurfactants. Herein, we describe for the first time the enzymatic synthesis of rhamnose fatty acid esters by the transesterification of rhamnose with fatty acid vinyl esters, using lipase

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d34a1a8fa481fc67ea4ca50b6aaa8429
https://doi.org/10.3390/ijms23042239

Acceptor Specificity of β-N-Acetylhexosaminidase from Talaromyces flavus: A Rational Explanation

Autor: Pilar Hoyos, Angel Rumbero, María J. Hernáiz, Lucie Petrásková, Alfredo H. Cabanillas, Cecilia García-Oliva, Pavla Bojarová, Vladimír Křen, Helena Pelantová, Natalia Kulik

Publikováno v: E-Prints Complutense: Archivo Institucional de la UCM
Universidad Complutense de Madrid
E-Prints Complutense. Archivo Institucional de la UCM
instname
International Journal of Molecular Sciences
Volume 20
Issue 24

Fungal &beta
N-acetylhexosaminidases, though hydrolytic enzymes in vivo, are useful tools in the preparation of oligosaccharides of biological interest. The &beta
N-acetylhexosaminidase from Talaromyces flavus is remarkable in terms of its

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d96ca903143d85532fc2c8aaf47caceb
https://eprints.ucm.es/id/eprint/67123/1/ijms-20-06181.pdf

Novel DNA Aptamers Against CCL21 Protein: Characterization and Biomedical Applications for Targeted Drug Delivery to T Cell-Rich Zones

Autor: María J. Hernáiz, Gerónimo Fernández, M. Elena Martín, Raveen Parboosing, Thirumala Govender, Víctor M. González, Louis Chonco, Rahul S. Kalhapure, Cecilia García-Oliva

Publikováno v: Nucleic acid therapeutics. 28(4)

The chemokine (C-C motif) ligand 21 (CCL21) is a cytokine that attracts CCR7-positive cells to the T cell (paracortical) zone of lymph nodes by directional migration of these cells along the CCL21 gradient. In this article, we sought to mimic this ch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85123d7be05185cfa9f707e59981d359
https://pubmed.ncbi.nlm.nih.gov/29733244