Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Cecilia Ericsson"'
Autor:
Anna Lindblom, Cecilia Ericsson, Therese Hagstedt, Ann Kjellstedt, Jan Oscarsson, Nicholas D Oakes
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0201367 (2018)
AIM:The aim of this study was to compare the plasma exposure and tissue accretion of docosahexaenoic acid (DHA) in response to oral dosing of free carboxylic acid (OM3CA) and ethyl ester (OM3EE) forms. MATERIALS AND METHODS:Sixteen adult male Wistar
Externí odkaz:
https://doaj.org/article/293ed40b6e124bba81d0384daaf23f2b
Autor:
Tord Inghardt, Thomas Antonsson, Cecilia Ericsson, Daniel Hovdal, Petra Johannesson, Carina Johansson, Ulrik Jurva, Johan Kajanus, Bengt Kull, Erik Michaëlsson, Anna Pettersen, Tove Sjögren, Henrik Sörensen, Kristina Westerlund, Eva-Lotte Lindstedt
Publikováno v:
Journal of Medicinal Chemistry. 65:11485-11496
Myeloperoxidase is a promising therapeutic target for treatment of patients suffering from heart failure with preserved ejection fraction (HFpEF). We aimed to discover a covalent myeloperoxidase inhibitor with high selectivity for myeloperoxidase ove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97ef1bcb1b44e92cc2a14d39e9d3d4b8
https://doi.org/10.1021/acs.jmedchem.1c02141
https://doi.org/10.1021/acs.jmedchem.1c02141
Autor:
Orlagh M. Feeney, Katie Ardipradja, Ka Fung Noi, Dharmini Mehta, Robert De Rose, Daniel Yuen, Angus P.R. Johnston, Lee Kingston, Cecilia Ericsson, Charles S. Elmore, Richard Hufton, David J. Owen, Marianne B. Ashford, Christopher J.H. Porter
Publikováno v:
Journal of Controlled Release. 348:420-430
As a malignant tumour of lymphatic origin, B-cell lymphoma represents a significant challenge for drug delivery, where effective therapies must access malignant cells in the blood, organs and lymphatics while avoiding off-target toxicity. Subcutaneou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd87b77b5dc91c4fdffa5fa891547b3a
https://doi.org/10.1016/j.jconrel.2022.05.041
https://doi.org/10.1016/j.jconrel.2022.05.041
Autor:
Tord Inghardt, Thomas Antonsson, Cecilia Ericsson, Daniel Hovdal, Petra Johannesson, Carina Johansson, Ulrik Jurva, Johan Kajanus, Bengt Kull, Erik Michaëlsson, Anna Pettersen, Tove Sjögren, Henrik Sörensen, Kristina Westerlund, Eva-Lotte Lindstedt
Publikováno v:
Journal of Medicinal Chemistry. 65:13482-13482
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::762527e04301766c31eec6829fdf10d1
https://doi.org/10.1021/acs.jmedchem.2c01533
https://doi.org/10.1021/acs.jmedchem.2c01533
Autor:
Paul H. Allen, Moya Caffrey, Michael J. Hickey, Cecilia Ericsson, Lee P. Kingston, Charles S. Elmore, Ryan A. Bragg
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 60:124-129
As part of a medicinal chemistry program aimed at developing a highly potent and selective cathepsin C inhibitor, tritium, carbon-14, and stable isotope-labeled materials were required. The synthesis of tritium-labeled methanesulfonate 5 was achieved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::078d768d2526de2d1d991348d9941c07
https://doi.org/10.1002/jlcr.3483
https://doi.org/10.1002/jlcr.3483
Autor:
Gunnar Grönberg, Göran N. Nilsson, Åsa Lindelöf, Cecilia Ericsson, Charles S. Elmore, Roger Simonsson
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 59:340-345
An AstraZeneca effort to identify a 5-lipoxygenase activating protein inhibitor with good drug-like properties resulted in the identification of AZD6642. To further understand its drug metabolism and pharmacokinetic properties, it was required labele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68588d3513a87a8d8323e28eda80148f
https://doi.org/10.1002/jlcr.3409
https://doi.org/10.1002/jlcr.3409
Autor:
Ola Åberg, Olof Eriksson, Gavin O'Mahony, Ewa Hellström-Lindahl, Peter Johnström, Stanko Skrtic, Cecilia Ericsson
Publikováno v:
Acta Diabetologica
Aims Molecular imaging of the free fatty acid receptor 1 (FFAR1) would be a valuable tool for drug development by enabling in vivo target engagement studies in human. It has also been suggested as a putative target for beta cell imaging, but the inhe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::370d299c91c4c4d54a30aba55a76dbf7
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-329002
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-329002
Synthesis of 2 C-14 labeled cathepsin C inhibitors: The use of a cyanide to displace a Benzotriazole
Autor:
Jonas Bergare, Lee P. Kingston, Gunnar Grönberg, Charles S. Elmore, Cecilia Ericsson, Hans Lönn, Song Chen
Publikováno v:
Journal of labelled compoundsradiopharmaceuticals. 60(6)
In support of the development of a new treatment for COPD, 2 C-14 labeled compounds were required for in vitro animal studies. The synthesis of nitrile [14 C]-1 was completed in 3 steps from C-14 labeled 4-bromobenzonitrile in accord with the previou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f81f67d0c70e3d0155e1a009bad4fef6
https://pubmed.ncbi.nlm.nih.gov/28324911
https://pubmed.ncbi.nlm.nih.gov/28324911
Publikováno v:
European Journal of Organic Chemistry. 2013:4756-4759
The authors gratefully acknowledge the financial support from the Research Council of Norway (grant number 165850/V30) and the University of Tromso for a scholarship to N. K.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12f31334dd8454dfe00d05d19b88ba7f
https://doi.org/10.1002/ejoc.201300710
https://doi.org/10.1002/ejoc.201300710
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 56:334-337
In support of a study designed to better understand the liver toxicity of ximelagatran, ximelagatran, and melagatran, hydroxymelagatran and ethylmelagatran were prepared in tritium labeled form. Incorporation of tritium was achieved by hydrogen isoto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c295cc95ab8c304704eb4be3ddfc46d
https://doi.org/10.1002/jlcr.3028
https://doi.org/10.1002/jlcr.3028