Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Cecilia E, Ström"'
Autor:
Thomas Helleday, Cecilia E. Ström
Publikováno v:
Biomolecules, Vol 2, Iss 4, Pp 635-649 (2012)
Treatments with Poly(adenosine diphosphate ribose) polymerase (PARP) inhibitors have offered patients carrying cancers with mutated BRCA1 or BRCA2 genes a new and in many cases effective option for disease control. There is potentially a large patien
Externí odkaz:
https://doaj.org/article/30eb83330ce548e1b1df793db7fe60d0
Autor:
Cecilia E. Ström, Helge Gad, Kumar Sanjiv, Nuno Amaral, Sean G. Rudd, Petra Groth, Ulrika Warpman Berglund, Thomas Helleday, Anna Hagenkort, Oliver Mortusewicz
Publikováno v:
Cancer Research
Reactive oxygen species (ROS) oxidize nucleotide triphosphate pools (e.g., 8-oxodGTP), which may kill cells if incorporated into DNA. Whether cancers avoid poisoning from oxidized nucleotides by preventing incorporation via the oxidized purine diphos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c38c5242fad52886da070df596f5345
Autor:
Cecilia E. Ström, Katarina Le Blanc, Anna Tolf, Emma Malmström, Lindsay C. Davies, Stellan Hertegård, Srinivasa Rao Nagubothu
Publikováno v:
Stem cells and development. 28(17)
Mesenchymal stromal cells (MSCs) promote wound healing by expediting the inflammatory phase. Local injection of MSCs into injured vocal folds (VFs) is effective in animal models, suggesting suitability for clinical translation. Despite their therapeu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d0f4e86d17eae0cdefc1a95e0ca9ab4
https://pubmed.ncbi.nlm.nih.gov/31244387
https://pubmed.ncbi.nlm.nih.gov/31244387
Autor:
Oliver Mortusewicz, Nuno Amaral, Helge Gad, Ulrika Warpman Berglund, Cecilia E. Ström, Petra Groth, Thomas Helleday, Anna Hagenkort, Sean G. Rudd
Publikováno v:
bioRxiv
Reactive oxygen species (ROS) oxidise nucleotide triphosphate pools (e.g., 8-oxodGTP), which may kill cells if incorporated into DNA. Whether cancers avoid poisoning from oxidised nucleotides by preventing incorporation via the oxidised purine diphos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5bffbd67cb82e7997e4706e6f1585f7
Autor:
Helge, Gad, Tobias, Koolmeister, Ann-Sofie, Jemth, Saeed, Eshtad, Sylvain A, Jacques, Cecilia E, Ström, Linda M, Svensson, Niklas, Schultz, Thomas, Lundbäck, Berglind Osk, Einarsdottir, Aljona, Saleh, Camilla, Göktürk, Pawel, Baranczewski, Richard, Svensson, Ronnie P-A, Berntsson, Robert, Gustafsson, Kia, Strömberg, Kumar, Sanjiv, Marie-Caroline, Jacques-Cordonnier, Matthieu, Desroses, Anna-Lena, Gustavsson, Roger, Olofsson, Fredrik, Johansson, Evert J, Homan, Olga, Loseva, Lars, Bräutigam, Lars, Johansson, Andreas, Höglund, Anna, Hagenkort, Therese, Pham, Mikael, Altun, Fabienne Z, Gaugaz, Svante, Vikingsson, Bastiaan, Evers, Martin, Henriksson, Karl S A, Vallin, Olov A, Wallner, Lars G J, Hammarström, Elisee, Wiita, Ingrid, Almlöf, Christina, Kalderén, Hanna, Axelsson, Tatjana, Djureinovic, Jordi, Carreras Puigvert, Maria, Häggblad, Fredrik, Jeppsson, Ulf, Martens, Cecilia, Lundin, Bo, Lundgren, Ingrid, Granelli, Annika, Jenmalm Jensen, Per, Artursson, Jonas A, Nilsson, Pål, Stenmark, Martin, Scobie
Publikováno v:
Nature. 544(7651)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a849c4dcef26131d22c77ff42f3cbc8e
https://pubmed.ncbi.nlm.nih.gov/24695224
https://pubmed.ncbi.nlm.nih.gov/24695224
Autor:
Cecilia E. Ström, Thomas Helleday
Publikováno v:
Biomolecules, Vol 2, Iss 4, Pp 635-649 (2012)
Biomolecules
Biomolecules
Treatments with Poly(adenosine diphosphate ribose) polymerase (PARP) inhibitors have offered patients carrying cancers with mutated BRCA1 or BRCA2 genes a new and in many cases effective option for disease control. There is potentially a large patien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88586c5076afd5481b8f94f22f2eee54
http://www.mdpi.com/2218-273X/2/4/635
http://www.mdpi.com/2218-273X/2/4/635
Autor:
Cecilia E. Ström, Grigory L. Dianov, Phillip S. Tait, David Finch, Thomas Helleday, Jason L. Parsons, Irina I. Dianova
XRCC1 is a scaffold protein that interacts with several DNA repair proteins and plays a critical role in DNA base excision repair (BER). XRCC1 protein is in a tight complex with DNA ligase IIIalpha (Lig III) and this complex is involved in the ligati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39805233aeb1aa432f054b5dc457826e
https://ora.ox.ac.uk/objects/uuid:cf9c7582-f2bb-40e7-aa6b-c02f90efb772
https://ora.ox.ac.uk/objects/uuid:cf9c7582-f2bb-40e7-aa6b-c02f90efb772
Autor:
Thomas Helleday, Keren Baranes-Bachar, Mickey C.T. Hu, Shih Ya Wang, Shelly Ziv-Lehrman, Cecilia E. Ström, Hava Segal-Raz, Young Min Chung, David J. Chen, Yosef Shiloh, Gilad Mass, Yaniv Lerenthal
Publikováno v:
EMBO reports. 12:713-719
The cellular response to double-strand breaks (DSBs) in DNA is a complex signalling network, mobilized by the nuclear protein kinase ataxia-telangiectasia mutated (ATM), which phosphorylates many factors in the various branches of this network. A mai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e54c81c6e7f8728c67212cc86140c48b
https://doi.org/10.1038/embor.2011.96
https://doi.org/10.1038/embor.2011.96
Correction: Corrigendum: MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool
Autor:
Ronnie P.-A. Berntsson, Aljona Saleh, Helge Gad, Martin Henriksson, Ingrid Almlöf, Cecilia E. Ström, Jordi Carreras Puigvert, Pål Stenmark, Fabienne Z. Gaugaz, Cecilia Lundin, Marie-Caroline Jacques-Cordonnier, Ulrika Warpman Berglund Thomas Helleday, Berglind Osk Einarsdottir, Roger Olofsson, Camilla Göktürk, Niklas Schultz, Maria Häggblad, Pawel Baranczewski, Anna-Lena Gustavsson, Olga Loseva, Per Artursson, Karl S. A. Vallin, Hanna Axelsson, Bo Lundgren, Tobias Koolmeister, Kia Strömberg, Christina Kalderén, Ulf Martens, Saeed Eshtad, Jonas Nilsson, Fredrik Johansson, Mikael Altun, Fredrik Jeppsson, Thomas Lundbäck, Evert Homan, Ann-Sofie Jemth, Martin Scobie, Anna Hagenkort, Lars Bräutigam, Annika Jenmalm Jensen, Andreas Höglund, Matthieu Desroses, Linda M. Svensson, Therese M. Pham, Richard Svensson, Kumar Sanjiv, Sylvain A. Jacques, Lars Hammarström, Elisee Wiita, Robert Gustafsson, Tatjana Djureinovic, Olov A. Wallner, Bastiaan Evers, Ingrid Granelli, Svante Vikingsson, Lars Johansson
Publikováno v:
Nature. 544:508-508
Nature 508, 215–221 (2014); doi:10.1038/nature13181 In this Article, the structure of compound TH650 (4) in Fig. 4a was drawn incorrectly; the correct structure is shown as Fig. 1 to this Corrigendum. Preparative, spectroscopic and biological data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e64f6574623c18f705fb61d14465e8fb
https://doi.org/10.1038/nature22083
https://doi.org/10.1038/nature22083
Autor:
Miguel López-Lázaro, Estefanía Burgos-Morón, José Manuel Calderón-Montaño, Nuria Pastor, Torkild Visnes, Manuel Luis Orta, Thomas Helleday, Cecilia E. Ström, Inmaculada Domínguez, Andreas Höglund
Publikováno v:
Nucleic Acids Research
Decitabine (5-aza-21-deoxycytidine, 5-azadC) is used in the treatment of Myelodysplatic syndrome (MDS) and Acute Myeloid Leukemia (AML). Its mechanism of action is thought to involve reactivation of genes implicated in differentiation and transformat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::878e4ac023f0eb92d0a2f513693abb7f
https://idus.us.es/xmlui/handle/11441/41298
https://idus.us.es/xmlui/handle/11441/41298