Výsledky vyhledávání - "Cecilia Bondjers"

Large-scale identification of genes implicated in kidney glomerulus development and function

Autor: Petter Mostad, Zhijie Xiao, Minoru Takemoto, Tatiana V. Petrova, Samuel Lundin, Naoyuki Miura, Liqun He, Jaakko Patrakka, Karl Tryggvason, Tore Samuelsson, Cecilia Bondjers, Christer Betsholtz, Ying Sun, Julia Asp, Yoshikazu Sado, Elisabet Wallgard, Kari Alitalo, Susan E. Quaggin, Jenny Norlin

Publikováno v: The EMBO Journal. 25:1160-1174

To advance our understanding of development, function and diseases in the kidney glomerulus, we have established and large-scale sequenced cDNA libraries from mouse glomeruli at different stages of development, resulting in a catalogue of 6053 differ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6cc44782f376bf32309595dee8dd32e
https://doi.org/10.1038/sj.emboj.7601014

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Expression of Platelet-Derived Growth Factor (PDGF) in the Epididymis and Analysis of the Epididymal Development in PDGF-A, PDGF-B, and PDGF Receptor β Deficient Mice

Autor: Giulia Ricci, Angela Catizone, M. Galdieri, Cecilia Bondjers, Andrea Ricci, Lucio Gnessi, Sabrina Basciani, Christer Betsholtz, Mario Arizzi, Stefania Mariani, Giovanni Spera, Marina Brama

Publikováno v: Biology of Reproduction. 70:168-177

The platelet-derived growth factor (PDGF) family of ligands and receptors play a pivotal role in the development of various organs. The critical importance of the PDGF-mediated signaling during embryonic development and adult physiology of the kidney

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03c53f55b15c21ea1eb9a441c41b2f60
https://doi.org/10.1095/biolreprod.103.019232

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Pericyte‐specific expression ofRgs5:implications for PDGF and EDG receptor signaling during vascular maturation

Autor: Cecilia Bondjers, Hyeseon Cho, Tohru Kozasa, John H. Kehrl, Christer Betsholtz

Publikováno v: The FASEB Journal. 17:1-17

RGS proteins finely tune heterotrimeric G-protein signaling. Implying the need for such fine-tuning in the developing vascular system, in situ hybridization revealed a striking and extensive expression pattern of Rgs5 in the arterial walls of E12.5-E

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e24e68c3f8386c05a9353396eb3bc3de
https://doi.org/10.1096/fj.02-0340fje

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Roles for PDGF-A and sonic hedgehog in development of mesenchymal components of the hair follicle

Autor: Cecilia Bondjers, Linda Karlsson, Christer Betsholtz

Publikováno v: Development. 126:2611-2621

Skin appendages, such as hair, develop as a result of complex reciprocal signaling between epithelial and mesenchymal cells. These interactions are not well understood at the molecular level. Platelet-derived growth factor-A (PDGF-A) is expressed in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf30c18c1fa54e92724a90389d1fa450
https://doi.org/10.1242/dev.126.12.2611

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Discovery of microvascular miRNAs using public gene expression data: miR-145 is expressed in pericytes and is a regulator of Fli1

Autor: Irmeli Barkefors, Bernhard Schermer, Peder Fredlund Fuchs, Guillem Genové, Johan Kreuger, Christine Kurschat, Erik Larsson, Per Lindahl, Cecilia Bondjers, Scott J. Harvey, Christelle Arrondel, Johan Heldin, Pär Gerwins, Thomas Benzing

Publikováno v: Genome Medicine
Genome Medicine, BioMed Central, 2009, 1 (11), pp.108. ⟨10.1186/gm108⟩
Genome Medicine, BioMed Central, 2009, 1 (11), pp.108. 〈10.1186/gm108〉

International audience; BACKGROUND: A function for the microRNA (miRNA) pathway in vascular development and angiogenesis has been firmly established. miRNAs with selective expression in the vasculature are attractive as possible targets in miRNA-base

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54356f3168214b58c248311e82db91b7
https://www.hal.inserm.fr/inserm-00663563/document

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Transcription Profiling of Platelet-Derived Growth Factor-B-Deficient Mouse Embryos Identifies RGS5 as a Novel Marker for Pericytes and Vascular Smooth Muscle Cells

Autor: Cecilia Bondjers, John H. Kehrl, Hyeseon Cho, Mattias Kalén, Alexandra Abramsson, Oliver Renner, Per Lindahl, Mats Hellström, Christer Betsholtz, Stefan J. Scheidl

Publikováno v: Scopus-Elsevier

All blood capillaries consist of endothelial tubes surrounded by mural cells referred to as pericytes. The origin, recruitment, and function of the pericytes is poorly understood, but the importance of these cells is underscored by the severe cardiov

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86561c64d821502771264e3afe774446
https://europepmc.org/articles/PMC1868109/

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Leydig cell loss and spermatogenetic arrest in platelet-derived growth factor (PDGF)-A-deficient mice

Autor: Chiayeng Wang, Stefania Mariani, Linda Karlsson, Sabrina Basciani, Giovanni Spera, Cecilia Bondjers, Lucio Gnessi, Mario Arizzi, Christer Betsholtz

Publikováno v: The Journal of Cell Biology

Platelet-derived growth factor (PDGF)- A–deficient male mice were found to develop progressive reduction of testicular size, Leydig cells loss, and spermatogenic arrest. In normal mice, the PDGF-A and PDGF-Rα expression pattern showed positive cel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e125f5dfd766eb76ad391bf9ed0ff805
http://hdl.handle.net/11573/255994

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PDGF-A and PDGF-B induces cardiac fibrosis in transgenic mice

Autor: Christer Betsholtz, Per Lindblom, Johanna Andrae, Cecilia Bondjers, Radiosa Gallini

Publikováno v: Experimental Cell Research. (2):282-290

Platelet-derived growth factors (PDGFs) and their receptors (PDGFRs) contribute to normal heart development. Deficient or abnormal expression of Pdgf and Pdgfr genes have a negative impact on cardiac development and function. The cellular effects of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b6305be7268176be12e52bc3e2d2fbb

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