Structural organization of erythrocyte membrane microdomains and their relation with malaria susceptibility

Autor: Anna Olivieri, Rebecca S. Lee, Federica Fratini, Cyrianne Keutcha, Mudit Chaand, Valentina Mangano, Francesco Celani, Stefania Mochi, Cecilia Birago, Silvio Paone, Felicia Grasso, Valentina Tirelli, Mario Falchi, Estela Shabani, Stefania Bertoncini, Bienvenu Sodiomon Sirima, Elisabetta Pizzi, David Modiano, Manoj T. Duraisingh, Marta Ponzi

Publikováno v: Communications Biology, Vol 4, Iss 1, Pp 1-10 (2021)

Olivieri et al. exploit floating properties of microdomain-associated proteins to investigate host proteins important for Plasmodium falciparum erythrocyte invasion. Using proteomic and bioinformatic approaches, they analyze clusters of protein abund

Externí odkaz: https://doaj.org/article/eb05db52ac9b4a6f8a32f15f23b8ee8e

An Integrated Approach to Explore Composition and Dynamics of Cholesterol-rich Membrane Microdomains in Sexual Stages of Malaria Parasite

Autor: Antonella Di Biase, Stefania Mochi, Tomasino Pace, Carla Raggi, Chiara Currà, Anna Olivieri, Cecilia Birago, Leonardo Picci, Elisabetta Pizzi, Gabriella Sferra, Federica Fratini, Carla Ferreri, Marta Ponzi, Felicia Grasso, Anna Sansone

Publikováno v: Molecular & cellular proteomics 16 (2017): 1801–1814. doi:10.1074/mcp.M117.067041
info:cnr-pdr/source/autori:Fratini F.; Raggi C.; Sferra G.; Birago C.; Sansone A.; Grasso F.; Curra C.; Olivieri A.; Pace T.; Mochi S.; Picci L.; Ferreri C.; Di Biase A.; Pizzi E.; Ponzi M./titolo:An integrated approach to explore composition and dynamics of cholesterol-rich membrane microdomains in sexual stages of malaria parasite/doi:10.1074%2Fmcp.M117.067041/rivista:Molecular & cellular proteomics/anno:2017/pagina_da:1801/pagina_a:1814/intervallo_pagine:1801–1814/volume:16

Membrane microdomains that include lipid rafts, are involved in key physiological and pathological processes and participate in the entry of endocellular pathogens. These assemblies, enriched in cholesterol and sphingolipids, form highly dynamic, liq

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4c975c6ae54dfbc8680a37e5bea3695
https://doi.org/10.1074/mcp.m117.067041

Targeted Terminal Deletions as a Tool for Functional Genomics Studies in Plasmodium

Autor: Cecilia Birago, Chris J. Janse, Marta Ponzi, Tomasino Pace, Andrew P. Waters, Raffaella Scotti

Publikováno v: Scopus-Elsevier

We describe a transfection system that induces terminal deletions at specific chromosome ends in malaria parasites using a linear construct containing telomeric repeats at one end and plasmodial sequences able to drive homologous recombination at the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52c20725456a48892b49a2ca471650ae
https://doi.org/10.1101/gr.140000

Developmental regulation of a Plasmodium gene involves the generation of stage-specific 5′ untranslated sequences1Note: Nucleotide sequence data reported in this paper are available in the EMBL, GenBank™ and DDJB data bases under the accession number AF 031904.1

Autor: Cecilia Birago, Marta Ponzi, Tomasino Pace, Leonardo Picci, Chris J. Janse

Publikováno v: Molecular and Biochemical Parasitology. 97:45-53

The B7 gene of Plasmodium berghei, highly conserved within the genus Plasmodium, encodes a nuclear protein most likely involved in chromatin assembly. In this study we describe the transcription pattern of B7 during asexual multiplication and sexual

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9984e3a6e4980d2807901e370815aedb
https://doi.org/10.1016/s0166-6851(98)00130-3

A chromatin-associated protein is encoded in a genomic region highly conserved in the Plasmodium genus

Autor: Marta Ponzi, Tomasino Pace, Leonardo Picci, Stefano Barca, Cecilia Birago

Publikováno v: Molecular and Biochemical Parasitology. 80:193-202

A single copy gene, pbB7, encoding a putative 26 kDa acidic protein has been isolated from Plasmodium berghei and appears to be part of a genomic region well conserved within the Plasmodium genus. The deduced amino acid sequence exhibits significant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faa44bbe95922c33a1f3a1164d2a665f
https://doi.org/10.1016/0166-6851(96)02680-1