Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Cecilia B. Marta"'
Autor:
Cecilia B. Marta, Steven E. Pfeiffer, Nancy H. Ruddle, Maja Maric, Peter Cresswell, Cheryl M. Bergman
Publikováno v:
The Journal of Immunology. 188:6001-6009
IFN-γ–inducible lysosomal thiol reductase (GILT) is an enzyme located in the Lamp-2–positive compartments of APC. GILT−/− mice are phenotypically normal, but their T cells exhibit reduced proliferation to several exogenously administered Ags
Publikováno v:
Glia. 57:935-946
Fibroblast growth factors (FGFs) and their receptors (FGFRs) initiate diverse cellular responses that contribute to the regulation of oligodendrocyte (OL) function. In order to understand the mechanisms by which FGFRs elicit these cellular responses,
Publikováno v:
Proceedings of the National Academy of Sciences. 102:13992-13997
Antibodies to myelin components are routinely detected in multiple sclerosis patients. However, their presence in some control subjects has made it difficult to determine their contribution to disease pathogenesis. Immunization of C57BL/6 mice with e
Autor:
Ava L. Taylor, Steven E. Pfeiffer, Cecilia B. Marta, Michael B. Montano, Christopher M. Taylor, Rashmi Bansal
Publikováno v:
Journal of Biological Chemistry. 280:8985-8993
Antibody-induced demyelination is an important component of pathology in multiple sclerosis. In particular, antibodies to myelin oligodendrocyte glycoprotein (MOG) are elevated in multiple sclerosis patients, and they have been implicated as mediator
Autor:
T. Kim, Susan Winkler, Cecilia B. Marta, Christopher M. Taylor, T. Coetzee, Rashmi Bansal, S. E. Pfeiffer
Publikováno v:
The Journal of Neuroscience. 23:5461-5471
Myelin oligodendrocyte glycoprotein (MOG) is, quantitatively, a relatively minor component of the myelin membrane. Nevertheless, peritoneal administration of MOG evokes potent cellular and humoral immunoreactivity, resulting in an experimental allerg
Autor:
Cecilia B. Marta, Pablo M. Paez, Amanda Pellegrino de Iraldi, Margarita Lopez, Eduardo F. Soto, Juana M. Pasquini
Publikováno v:
Neurochemical Research. 28:101-110
Previous findings from our laboratories indicate that the intracranial injection of apotransferrin (aTf) in neonatal rats produces an accelerated oligodendrocyte maturation and an enhanced production and deposition of myelin membranes in the brain. T
Publikováno v:
Journal of Neuroscience Research. 69:488-496
Apotransferrin (aTf), intracranially administered into newborn rats, produces increased myelination with marked increases in the levels of myelin basic protein (MBP), phospholipids and galactolipids, and mRNAs of MBP and 2', 3' cyclic nucleotide 3'-p
Autor:
Mario M. Zakin, Bruno Baron, J.M. Pasquini, E.H. Ortiz, Cecilia B. Marta, Marta E. Hallak, Eduardo F. Soto, Florian Guillou
Publikováno v:
Developmental Neuroscience. 24:242-251
Apotransferrin injected intracranially into young rats has been shown in our laboratories to induce an early differentiation of oligodendroglial cells and an increased deposition of myelin. The expression of some myelin-specific proteins such as myel
Anxiolytic-like behavior in rats is induced by the neonatal intracranial injection of apotransferrin
Publikováno v:
Journal of Neuroscience Research. 63:196-199
To determine whether neonatal intracranial injection of apotransferrin (aTf), which increases myelin deposition, has behavioral effects in rats, 3-day-old rats were intracranially injected with 350 ng of aTf and tested at 25 and 60 days of age. An an
Publikováno v:
Neurochemical Research. 25:627-635
We have recently shown that sustained neonatal hyperthyroidism in the rat activates apoptosis of oligodendroglial cells (OLGc) and that inhibition of the proteasome-ubiquitin (Ub) pathway by lactacystin produces increased apoptosis in cerebellar gran