Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Cecilia Austin"'
Autor:
Douglas A. Marchuk, Meijing Wu, Romuald Girard, Rhonda Lightle, David A. McDonald, Issam A. Awad, Carol J. Gallione, Robert Shenkar, Hussein A. Zeineddine, Peter Pytel, Cecilia Austin, Ying Cao, James K. Liao, Autumn Rorrer, Thomas C. Moore, Lingjiao Zhang, Changbin Shi
Publikováno v:
Stroke. 48:187-194
Background and Purpose— We sought to compare the effect of chronic treatment with commonly tolerated doses of Fasudil, a specific RhoA kinase (ROCK) inhibitor, and simvastatin (with pleiotropic effects including ROCK inhibition) on cerebral caverno
Autor:
Rhonda Lightle, Ying Cao, Douglas A. Marchuk, Cecilia Austin, Issam A. Awad, Maged D Fam, Thomas R. Moore, Lingjiao Zhang, Meijing Wu, Carol J. Gallione, Robert Shenkar, Autumn Rorrer, Hussein A. Zeineddine, Murat Gunel, Romuald Girard, Angeliki Louvi, Changbin Shi
Publikováno v:
Journal of Neuroimmune Pharmacology. 11:369-377
Cerebral cavernous malformations (CCMs) are relatively common vascular malformations, characterized by increased Rho kinase (ROCK) activity, vascular hyper-permeability and the presence of blood degradation products including non-heme iron. Previous
Autor:
Anthony K. Shum, Mark S. Anderson, Cecilia Austin, Wen Lu, Erich C. Strauss, Jason DeVoss, Anna K. Krawisz, Kellsey Johannes, Ting Yang, Peter L. Wang, Norbert P. LeClair
Publikováno v:
The Journal of Immunology. 181:4072-4079
Mutations in the Aire gene result in a clinical phenomenon known as Autoimmune Polyglandular Syndrome (APS) Type I, which classically manifests as a triad of adrenal insufficiency, hypoparathyroidism, and chronic mucocutaneous infections. In addition
Autor:
Robert Shenkar, Changbin Shi, David McDonald, Cecilia Austin, Autumn Rorrer, Carol Gallione, Lingjiao Zhang, Douglas Marchuk, Issam Awad
Publikováno v:
Stroke. 46
Objective: To compare therapeutic effect on cerebral cavernous malformation (CCM) genesis and maturation of fasudil (specific RhoA kinase inhibitor) and simvastatin (with pleiotropic effects including Rho inhibition) in two heterozygous murine models
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