A nonneutralizing antibody as cause of prothrombin deficiency in a patient with follicular lymphoma

Autor: Cecilia Augustsson, Knut Taxbro, Karin Strandberg, Eva Zetterberg

Publikováno v: Clinical Case Reports, Vol 12, Iss 1, Pp n/a-n/a (2024)

Key Clinical Message Acquired inhibitors of blood coagulation are rare but of clinical importance. Prothrombin is a vitamin K‐dependent protein, and acquired antibodies toward prothrombin are often associated with the presence of lupus anticoagulan

Externí odkaz: https://doaj.org/article/8444a432b80944588a05ae7877bd1f75

Vitamin K Effects on Gas6 and Soluble Axl Receptors in Intensive Care Patients: An Observational Screening Study

Autor: Ulf Schött, Cecilia Augustsson, Luukas Lilover, Caroline Ulfsdotter Nilsson, Louise Walther-Sturesson, Thomas Kander

Publikováno v: Nutrients, Vol 13, Iss 11, p 4101 (2021)

Growth arrest-specific gene 6 protein (Gas6) is avitamin K-dependent tissue bound protein. Gas6 has been shown to promote growth and therapy resistance among different types of cancer as well as thromboembolism. The aim of this prospective screening

Externí odkaz: https://doaj.org/article/6cb86dea8f2f4edf95dff760a8cec8be

Methods for anti‐factor VIII antibody levels in haemophilia A patients – validation of a multiplex immunoassay and comparability with assays measuring non‐neutralising and neutralising antibodies (inhibitors)

Autor: Myriam Martin, Cecilia Augustsson, Vivian Lind, Riam Al‐Sabti, My Chi Lam, Nadine G. Andersson, Karin Strandberg

Publikováno v: Haemophilia. 29:336-347

The development of neutralising (inhibitors) and non-neutralising antibodies (NNAs) is a complication to factor replacement therapy in haemophilia. The diagnostic methods available lack standardisation, have high inter-laboratory variation, and false

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26b2ca47bd262e9eeb83547fa4f2396a
https://doi.org/10.1111/hae.14669

Validation of factor VIII activity for monitoring standard and extended half-life products and correlation to thrombin generation assays

Autor: Karin Strandberg, Jan Astermark, Eva Norström, Myriam Martin, Vivian Lind, Cecilia Augustsson

Publikováno v: Haemophilia : the official journal of the World Federation of HemophiliaREFERENCES. 27(3)

Introduction Monitoring replacement therapy with standard and extended half-life (EHL) products is challenging, since one-stage assay (OSA) and chromogenic substrate assay (CSA) results may differ significantly. Recent recommendations include local v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16a221b4ca852ace65a8e4cc51716186
https://pubmed.ncbi.nlm.nih.gov/33866649

Monitoring standard and extended half-life products in hemophilia: Assay discrepancies for factor VIII and IX in pre- and postinfusion samples

Autor: Eva Norström, Cecilia Augustsson, Nadine G. Andersson, Eva Zetterberg, Jan Astermark, Karin Strandberg

Publikováno v: Research and Practice in Thrombosis and Haemostasis
Research and Practice in Thrombosis and Haemostasis, Vol 4, Iss 7, Pp 1114-1120 (2020)

Background Monitoring hemophilia treatment with extended half-life products is challenging for coagulation laboratories since factor assays may show substantial differences between results obtained with the one-stage assay (OSA) and the chromogenic s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a900fd94e97cfb5c5d150502803483d0
https://pubmed.ncbi.nlm.nih.gov/33134777