Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Cecile V. Denis"'
Autor:
Caterina Casari, Remi Favier, Paulette Legendre, Alexandre Kauskot, Frederic Adam, Veronique Picard, Peter J. Lenting, Cecile V. Denis, Valerie Proulle
Publikováno v:
Therapeutic Advances in Hematology, Vol 13 (2022)
This report describes the first case of splenic injury in a patient with p.V1316M-associated von Willebrand disease type 2B (VWD2B) with chronic thrombocytopenia, successfully treated with nonoperative management including von Willebrand factor (VWF)
Externí odkaz:
https://doaj.org/article/f46a35a8466e49af9e0fca1439be9097
Autor:
Berenice Schell, Celine Desconclois, Xavier Mariette, Cecile Goujard, Peter J. Lenting, Cecile V. Denis, Valerie Proulle
Publikováno v:
Haematologica, Vol 106, Iss 1 (2020)
Externí odkaz:
https://doaj.org/article/6272e7e6041c40748b5821b9a1e410c2
Autor:
Stéphanie Roullet, Norman Luc, Julie Rayes, Jean Solarz, Dante Disharoon, Andrew J Ditto, Emily Gahagan, Christa Pawlowski, Thibaud Sefiane, Frédéric Adam, Caterina Casari, Olivier D. Christophe, Michael A Bruckman, Peter J Lenting, Anirban Sen Gupta, Cecile V Denis
Publikováno v:
Blood.
The lack of innovation in Von Willebrand disease (VWD) originates from many factors including the complexity and heterogeneity of the disease but also from a lack of recognition of the impact of the bleeding symptoms experienced by VWD patients. Rece
Autor:
Claire, Kizlik-Masson, Ivan, Peyron, Stéphane, Gangnard, Gaelle Claire, Le Goff, Solen, Lenoir, Sandra, Damodaran, Marie, Clavel, Stéphanie, Roullet, Veronique, Regnault, Antoine, Rauch, Flavien, Vincent, Emmanuelle, Jeanpierre, Annabelle, Dupont, Catherine, Ternisien, Thibault, Donnet, Olivier D, Christophe, Eric, Van Belle, Cecile V, Denis, Caterina, Casari, Sophie, Susen, Peter J, Lenting
Publikováno v:
Blood.
Von Willebrand factor (VWF) is a multimeric protein, the size of which is regulated via ADAMTS13-mediated proteolysis within the A2-domain. We aimed to isolate nanobodies distinguishing between proteolyzed and non-proteolyzed VWF, leading to the iden
Autor:
Thibaud Sefiane, Hortense Maynadié, Carmen Escurola Ettingshausen, Vincent Muczynski, Xavier Heiligenstein, Julien Dumont, Olivier D. Christophe, Cécile V. Denis, Caterina Casari, Peter J. Lenting
Publikováno v:
Haematologica, Vol 109, Iss 6 (2023)
Recombinant factor VIII (rFVIII), rFVIIIFc and emicizumab are established treatment options in the management of hemophilia A. Each has its unique mode of action, which can influence thrombin generation kinetics and therefore also the kinetics of thr
Externí odkaz:
https://doaj.org/article/87dfb0cfe60b4523b7deb3413f713473
Autor:
Reinhard Schneppenheim, Natalie Hellermann, Maria Alexandra Brehm, Ulrike Klemm, Tobias Obser, Volker Huck, Stefan W Schneider, Cecile V. Denis, Alexander Tischer, Matthew Auton, Winfried Maerz, Emma-Ruoqi Xu, Matthias Wilmanns, Rainer B. Zotz
Publikováno v:
Blood. 132:2459-2459
The frequent von Willebrand factor (VWF) variant p.Phe2561Tyr is located within the C4 domain, which also harbors the platelet GPIIb/IIIa-binding RGD sequence. To investigate its potential effect on hemostasis, we genotyped 865 patients with coronary
Autor:
Marie‐Daniéla Dubois, Ivan Peyron, Olivier‐Nicolas Pierre‐Louis, Serge Pierre‐Louis, Johalène Rabout, Pierre Boisseau, Annika deJong, Sophie Susen, Jenny Goudemand, Rémi Neviere, Pascal Fuseau, Olivier D. Christophe, Peter J. Lenting, Cécile V. Denis, Caterina Casari
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 6, Iss 4, Pp n/a-n/a (2022)
Abstract Background Von Willebrand disease was diagnosed in two Afro‐Caribbean patients and sequencing of the VWF gene (VWF) revealed the presence of multiple variants located throughout the gene, including variants located in the D4 domain of VWF:
Externí odkaz:
https://doaj.org/article/b5a5473594134f32afc891cac997479f
Autor:
Ivan Peyron, Claire Kizlik‐Masson, Marie‐Daniéla Dubois, Sénadé Atsou, Stephen Ferrière, Cécile V. Denis, Peter J. Lenting, Caterina Casari, Olivier D. Christophe
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 4, Iss 7, Pp 1087-1110 (2020)
Abstract Hemostasis is a complex process involving the concerted action of molecular and vascular components. Its basic understanding as well as diagnostic and therapeutic aspects have greatly benefited from the use of monoclonal antibodies. Interest
Externí odkaz:
https://doaj.org/article/28833a87b34b49a9b8815afa9a9a3cb5
Autor:
Dominique Lasne, Tiffany Pascreau, Sadyo Darame, Marie‐Charlotte Bourrienne, Peggy Tournoux, Aurélien Philippe, Sara Ziachahabi, Felipe Suarez, Ambroise Marcais, Annabelle Dupont, Cécile V. Denis, Alexandre Kauskot, Delphine Borgel
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 4, Iss 5, Pp 813-822 (2020)
Abstract Background Correct diagnosis of the cause of thrombocytopenia is crucial for the appropriate management of patients. Hyposialylation/desialylation (characterized by abnormally high β‐galactose exposure) accelerates platelet clearance and
Externí odkaz:
https://doaj.org/article/fb8cc2610a0a4df0821dc427566bb3e6
Autor:
Lamia Lamrani, Frédéric Adam, Christelle Soukaseum, Cécile V. Denis, Hana Raslova, Jean‐Philippe Rosa, Marijke Bryckaert
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 6, Iss 2, Pp n/a-n/a (2022)
Abstract Background Filamin (FLN) regulates many cell functions through its scaffolding activity cross‐linking cytoskeleton and integrins. FLN was shown to inhibit integrin activity, but the exact mechanism remains unclear. Objectives The aim of th
Externí odkaz:
https://doaj.org/article/8a66c3162756480ca903cda5b86d834b