Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Cecile T. J. Holweg"'
Autor:
Thomas R. Murphy, William Busse, Cecile T. J. Holweg, Yamina Rajput, Karina Raimundo, Craig S. Meyer, Arpamas Seetasith, Sachin Gupta, Ahmar Iqbal, Robert J. Kaner
Publikováno v:
BMC Pulmonary Medicine, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background Although asthma does not appear to be a risk factor for severe coronavirus disease 2019 (COVID-19), outcomes could vary for patients with different asthma subtypes. The objective of this analysis was to compare COVID-19 outcomes i
Externí odkaz:
https://doaj.org/article/37b26bc28f82427aae0d9de239596c29
Autor:
Diana Chang, Julie Hunkapiller, Tushar Bhangale, Jens Reeder, Kiran Mukhyala, Jennifer Tom, Amy Cowgill, Jan Vogel, William F. Forrest, Zia Khan, Amy Stockwell, Mark I. McCarthy, Tracy L. Staton, Julie Olsson, Cecile T. J. Holweg, Dorothy S. Cheung, Hubert Chen, Matthew J. Brauer, Robert R. Graham, Timothy Behrens, Mark S. Wilson, Joseph R. Arron, David F. Choy, Brian L. Yaspan
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Genome-wide association studies (GWAS) have identified many common variant loci associated with asthma susceptibility, but few studies investigate the genetics underlying moderate-to-severe asthma risk. Here, we present a whole-genome sequen
Externí odkaz:
https://doaj.org/article/5fa4592260184e79882d694bb0b47a44
Autor:
Taha Al‐Shaikhly, Ryan C. Murphy, Ying Lai, Charles W. Frevert, Jason S. Debley, Steven F. Ziegler, Kit Wong, Guiquan Jia, Cecile T. J. Holweg, Michael C. Peters, Teal S. Hallstrand
Publikováno v:
Respirology. 28:491-494
Autor:
P. Jane McDowell, John Busby, Catherine E. Hanratty, Ratko Djukanovic, Ashley Woodcock, Samantha Walker, Timothy Colin Hardman, Joseph R. Arron, David F. Choy, Peter Bradding, Chris E. Brightling, Rekha Chaudhuri, Douglas Cowan, Adel H. Mansur, Stephen J. Fowler, Sarah E. Diver, Peter Howarth, James Lordan, Andrew Menzies-Gow, Timothy Harrison, Douglas S. Robinson, Cecile T. J. Holweg, John G. Matthews, Ian D. Pavord, Liam G. Heaney
Publikováno v:
Am J Respir Crit Care Med
Rationale: The past 25 years have seen huge progress in understanding of the pathobiology of type-2 (T2) asthma, identification of measurable biomarkers, and the emergence of novel monoclonal antibody treatments. Although present in a minority of pat
Autor:
Rennie L Rhee, Cecile T J Holweg, Kit Wong, David Cuthbertson, Simon Carette, Nader A Khalidi, Curry L Koening, Carol A Langford, Carol A McAlear, Paul A Monach, Larry W Moreland, Christian Pagnoux, Philip Seo, Ulrich Specks, Antoine G Sreih, Steven R Ytterberg, Peter A Merkel, Vasculitis Clinical Research Consortium
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0205768 (2018)
OBJECTIVE:Identification of a biomarker for disease activity in eosinophilic granulomatosis with polyangiitis (EGPA; Churg-Strauss) remains an unmet need. This study examined the value of serum periostin, a marker of type 2 inflammation, as a measure
Externí odkaz:
https://doaj.org/article/5033a7268f404b9498d249f71033979a
Autor:
Samuel, DeLeon, Franco, Barsanti, Cecile T J, Holweg, Bongin, Yoo, Blaine, Creasy, Michael E, Wechsler
Publikováno v:
The Journal of Allergy and Clinical Immunology: In Practice. 10:2181-2183.e1
Autor:
Stanley J. Szefler, Graham Roberts, Adalberto S. Rubin, Stefan Zielen, Piotr Kuna, Oral Alpan, Judith Anzures‐Cabrera, Qiang Chen, Cécile T. J. Holweg, Janusz Kaminski, Wendy S. Putnam, John G. Matthews, Nikhil Kamath
Publikováno v:
Clinical and Translational Allergy, Vol 12, Iss 7, Pp n/a-n/a (2022)
Abstract Background Lebrikizumab is a monoclonal antibody that modulates activity of interleukin‐13. The Phase 3 ACOUSTICS study assessed lebrikizumab efficacy and safety in adolescents with uncontrolled asthma despite standard‐of‐care treatmen
Externí odkaz:
https://doaj.org/article/95330c9a733f48b0baef545bd3c87bf6
Publikováno v:
Frontiers in Medicine, Vol 4 (2017)
Asthma is characterized by episodic, reversible airflow obstruction associated with variable levels of inflammation. Over the past several decades, there has been an increasing appreciation that the clinical presentation of asthma comprises a diverse
Externí odkaz:
https://doaj.org/article/a4d822c565c54abf9eb7764c43d18ccf