Vascular remodeling is governed by a VEGFR3-dependent fluid shear stress set point

Autor: Nicolas Baeyens, Stefania Nicoli, Brian G Coon, Tyler D Ross, Koen Van den Dries, Jinah Han, Holly M Lauridsen, Cecile O Mejean, Anne Eichmann, Jean-Leon Thomas, Jay D Humphrey, Martin A Schwartz

Publikováno v: eLife, Vol 4 (2015)

Vascular remodeling under conditions of growth or exercise, or during recovery from arterial restriction or blockage is essential for health, but mechanisms are poorly understood. It has been proposed that endothelial cells have a preferred level of

Externí odkaz: https://doaj.org/article/a35cb0e296dd4d8c953df6a4fd501a55

Syndecan 4 is required for endothelial alignment in flow and atheroprotective signaling

Autor: John Rhodes, Martin A. Schwartz, David D. Simon, Cecile O. Mejean, Federico Corti, Tyler D Ross, Thomas Z. Wang, Jay D. Humphrey, Michael Simons, Nicolas Baeyens, Mary Jo Mulligan-Kehoe

Publikováno v: Baeyens, N, Mulligan-Kehoe, M J, Corti, F, Simon, D D, Ross, T D, Rhodes, J M, Wang, T Z, Mejean, C O, Simons, M, Humphrey, J & Schwartz, M A 2014, ' Syndecan 4 is required for endothelial alignment in flow and atheroprotective signaling ', Proceedings of the National Academy of Sciences of the United States of America, vol. 111, no. 48, pp. 17308-13 . https://doi.org/10.1073/pnas.1413725111

Atherosclerotic plaque localization correlates with regions of disturbed flow in which endothelial cells (ECs) align poorly, whereas sustained laminar flow correlates with cell alignment in the direction of flow and resistance to atherosclerosis. We

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b1dec36bc562c2070fcc3a82ae0b2bf
https://doi.org/10.1073/pnas.1413725111

Membrane tension maintains cell polarity by confining signals to the leading edge during neutrophil migration

Autor: Cecile O. Mejean, Steven J. Altschuler, Orion D. Weiner, Rostislav Boltyanskiy, Sigurd Angenent, Lani F. Wu, Eric R. Dufresne, Alexandra Jilkine, Andrew R. Houk

Publikováno v: Cell. 148(1-2)

SummaryLittle is known about how neutrophils and other cells establish a single zone of actin assembly during migration. A widespread assumption is that the leading edge prevents formation of additional fronts by generating long-range diffusible inhi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90b130e8ce9aa8e0244c5867525332e5
https://pubmed.ncbi.nlm.nih.gov/22340489

Electrostatic interactions of colloidal particles in nonpolar solvents: role of surface chemistry and charge control agents

Autor: Eric R. Dufresne, Sainis Sunil Krishna, Cecile O. Mejean, Vincent Germain

Publikováno v: Langmuir : the ACS journal of surfaces and colloids. 24(4)

We study the electrostatic and hydrodynamic interactions of colloidal particles in nonpolar solvents. Using blinking optical tweezers, we can extract the screening length, kappa-1, the effective surface potential, |ezeta*|, and the hydrodynamic radiu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25a7962c7c477a92f93da93deb2055a1
https://pubmed.ncbi.nlm.nih.gov/18062711

Vascular remodeling is governed by a VEGFR3-dependent fluid shear stress set point

Autor: Jay D. Humphrey, Nicolas Baeyens, Cecile O. Mejean, Brian G. Coon, Jinah Han, Holly M. Lauridsen, Martin A. Schwartz, Stefania Nicoli, Jean-Leon Thomas, Koen van den Dries, Anne Eichmann, Tyler D Ross

Publikováno v: eLife
eLife, eLife Sciences Publication, 2015, 4, pp.e04645. ⟨10.7554/eLife.04645⟩
eLife, eLife Sciences Publication, 2015, 4, pp.e04645. 〈10.7554/eLife.04645〉
eLife, 4
eLife, 2015, 4, pp.e04645. ⟨10.7554/eLife.04645⟩
eLife, Vol 4 (2015)
Elife, 4, e04645
Elife, 4, pp. e04645
Baeyens, N, Nicoli, S, Coon, B G, Ross, T D, Van den Dries, K, Han, J, Lauridsen, H M, Mejean, C O, Eichmann, A, Thomas, J-L, Humphrey, J D & Schwartz, M A 2015, ' Vascular remodeling is governed by a VEGFR3-dependent fluid shear stress set point ', eLife, vol. 4 . https://doi.org/10.7554/eLife.04645

Vascular remodeling under conditions of growth or exercise, or during recovery from arterial restriction or blockage is essential for health, but mechanisms are poorly understood. It has been proposed that endothelial cells have a preferred level of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5361bda6cdd4449695c345eaf77afd3
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/154418