Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Cecile E.M.T. Beerens"'
Autor:
Trisha Kers, Sieger Leenstra, Clemens M F Dirven, Stanley Van, Judith Van den Burg, Youri Hoogstrate, Pim J. French, Cassandra Verheul, Ioannis Ntafoulis, Martine L.M. Lamfers, Miao Chien, Cecile E.M.T. Beerens, Federica Fabro
Publikováno v:
Neuro-Oncology. 23:vi219-vi219
INTRODUCTION The search for effective therapies for gliomas is progressively moving towards patient-specific medicine. In order to test patient-tailored therapies, it is vital to develop protocols for reliable establishment of patient-derived glioma
Autor:
Mustafa Suker, Marion de Jong, Melissa van Kranenburg, Michael Doukas, Dik C. van Gent, Casper H.J. van Eijck, Julie Nonnekens, Cecile E.M.T. Beerens
Publikováno v:
Theranostics
Theranostics, 6(11), 1821-1832. Ivyspring International Publisher
Theranostics, 6(11), 1821-1832. Ivyspring International Publisher
Metastases expressing tumor-specific receptors can be targeted and treated by binding of radiolabeled peptides (peptide receptor radionuclide therapy or PRRT). For example, patients with metastasized somatostatin receptor-positive neuroendocrine tumo
Autor:
Cecile E.M.T. Beerens, Otto C. Boerman, Wytske M. van Weerden, Marion de Jong, Sandra Heskamp, Julie Nonnekens, Kristell L.S. Chatalic, Hans-Jürgen Wester, Janneke D.M. Molkenboer-Kuenen, Frank Bruchertseifer, Alfred Morgenstern, Margret Schottelius, Dik C. van Gent, Joke Veldhoven-Zweistra
Publikováno v:
Cancer Biotherapy & Radiopharmaceuticals, 32(2), 67-73. Mary Ann Liebert Inc.
Cancer Biotherapy & Radiopharmaceuticals, 32, 67-73
Cancer Biotherapy & Radiopharmaceuticals, 32, 2, pp. 67-73
Cancer Biotherapy & Radiopharmaceuticals, 32, 67-73
Cancer Biotherapy & Radiopharmaceuticals, 32, 2, pp. 67-73
Item does not contain fulltext BACKGROUND: Up to now, prostate-specific membrane antigen (PSMA)-targeted radionuclide therapy mainly focused on beta-emitting radionuclides. Herein, two new 213Bi-labeled agents for PSMA-targeted alpha therapy of prost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8884d21f6a505e307397aa775826ffc
https://pure.eur.nl/en/publications/674ca53e-7d77-4e49-993b-8200e07e3c65
https://pure.eur.nl/en/publications/674ca53e-7d77-4e49-993b-8200e07e3c65
Autor:
Bep Smit, Cecile E.M.T. Beerens, Jeroen Essers, Jan H.J. Hoeijmakers, Joanna Wesoly, Mies L. G. Dronkert, Claire Wyman, Rudi W. Hendriks, Roland Kanaar
Publikováno v:
DNA Repair, 1, 779-793. Elsevier
Homologous recombination is one of the major pathways for repair of DNA double-strand breaks (DSBs). Important proteins in this pathway are Rad51 and Rad54. Rad51 forms a nucleoprotein filament on single-stranded DNA (ssDNA) that mediates pairing wit
Autor:
Leena Peltonen, Grazia M.S. Mancini, P. J. Van Der Spek, Cecile E.M.T. Beerens, Hans Galjaard, Adrie C. Havelaar, M. Joosse, Elly Verbeek, Pertti Aula, Nina Aula, Frans W. Verheijen
Publikováno v:
Nature Genetics, 23, 462-465. Nature Publishing Group
Sialic acid storage diseases (SASD, MIM 269920) are autosomal recessive neurodegenerative disorders that may present as a severe infantile form (ISSD) or a slowly progressive adult form, which is prevalent in Finland (Salla disease). The main symptom
Publikováno v:
FEBS Letters. Journal for the Rapid Publication of Short Reports in Biochemistry ....., 446, 65-68. Wiley-Blackwell
Transport of sialic acid through the lysosomal membrane is defective in the human sialic acid storage disease. The mammalian sialic acid carrier has a wide substrate specificity for acidic monosaccharides. Recently, we showed that also non-sugar mono
Autor:
Adrie C. Havelaar, Frans W. Verheijen, Cecile E.M.T. Beerens, Grazia M.S. Mancini, Ragonda M.A. Souren
Publikováno v:
Journal of Biological Chemistry. 273:34568-34574
Sialic acid and glucuronic acid are monocarboxylated monosaccharides, which are normally present in sugar side chains of glycoproteins, glycolipids, and glycosaminoglycans. After degradation of these compounds in lysosomes, the free monosaccharides a
Publikováno v:
Proceedings of the National Academy of Sciences. 89:6609-6613
The lysosomal carrier for the acidic monosaccharides sialic acid and glucuronic acid was solubilized from rat liver lysosomal membranes and reconstituted into phospholipid vesicles. Membrane proteins were extracted from lysosomal membranes with Trito
Publikováno v:
Journal of Clinical Investigation. 87:1329-1335
A defective efflux of free sialic acid from the lysosomal compartment has been found in the clinically heterogeneous group of sialic acid storage disorders. Using radiolabeled sialic acid (NeuAc) as a substrate, we have recently detected and characte
Publikováno v:
Journal of Biological Chemistry. 265:12380-12387
Lysosomal membrane vesicles isolated from rat liver were exploited to analyze the mechanism of glucose transport across the lysosomal membrane. Uptake kinetics of [14C]D-glucose showed a concentration-dependent saturable process, typical of carrier-m