Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Cecile Delarasse"'
Autor:
Laetitia Douguet, Serena Janho dit Hreich, Jonathan Benzaquen, Laetitia Seguin, Thierry Juhel, Xavier Dezitter, Christophe Duranton, Bernhard Ryffel, Jean Kanellopoulos, Cecile Delarasse, Nicolas Renault, Christophe Furman, Germain Homerin, Chloé Féral, Julien Cherfils-Vicini, Régis Millet, Sahil Adriouch, Alina Ghinet, Paul Hofman, Valérie Vouret-Craviari
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
A limited percentage of patients with non-small cell lung cancer respond to immunotherapy. Here the authors show that HEI3090, a chemical positive modulator of the purinergic P2RX7 receptor, promotes IL-18 mediated anti-tumor immune responses and sen
Externí odkaz:
https://doaj.org/article/d9f2cc20554a4d0e92405e7e329a31b4
Autor:
Christophe Roubeix, Caroline Nous, Sébastien Augustin, Kaitryn E. Ronning, Thibaud Mathis, Frédéric Blond, Pauline Lagouge-Roussey, Sergio Crespo-Garcia, Patrick M. Sullivan, Emmanuel L. Gautier, Nadine Reichhart, José-Alain Sahel, Marie E. Burns, Michel Paques, Torben Lykke Sørensen, Olaf Strauss, Xavier Guillonneau, Cécile Delarasse, Florian Sennlaub
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-17 (2024)
Abstract Age-related macular degeneration (AMD) is invariably associated with the chronic accumulation of activated mononuclear phagocytes in the subretinal space. The mononuclear phagocytes are composed of microglial cells but also of monocyte-deriv
Externí odkaz:
https://doaj.org/article/15a2fe8398d24307833b4ae362a8cd9b
Autor:
Sebastien Augustin, Marion Lam, Sophie Lavalette, Anna Verschueren, Frédéric Blond, Valérie Forster, Lauriane Przegralek, Zhiguo He, Daniel Lewandowski, Alexis-Pierre Bemelmans, Serge Picaud, José-Alain Sahel, Thibaud Mathis, Michel Paques, Gilles Thuret, Xavier Guillonneau, Cécile Delarasse, Florian Sennlaub
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-19 (2023)
Abstract Retinal melanosome/melanolipofuscin-containing cells (MCCs), clinically visible as hyperreflective foci (HRF) and a highly predictive imaging biomarker for the progression of age-related macular degeneration (AMD), are widely believed to be
Externí odkaz:
https://doaj.org/article/36478ff34584497caa06ecb1e684bdde
Autor:
Guillaume Blot, Rémi Karadayi, Lauriane Przegralek, Thérèse-Marie Sartoris, Hugo Charles-Messance, Sébastien Augustin, Pierre Negrier, Frédéric Blond, Frida Paulina Muñiz-Ruvalcaba, David Rivera-de la Parra, Lucile Vignaud, Aude Couturier, José-Alain Sahel, Niyazi Acar, Aida Jimenez-Corona, Cécile Delarasse, Yonathan Garfias, Florian Sennlaub, Xavier Guillonneau
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 19 (2023)
Type 2 diabetes mellitus (T2DM), characterized by hyperglycemia and dyslipidemia, leads to nonproliferative diabetic retinopathy (NPDR). NPDR is associated with blood-retina barrier disruption, plasma exudates, microvascular degeneration, elevated in
Externí odkaz:
https://doaj.org/article/a428d0dd6e824e1eaa04dc9d73afec22
Publikováno v:
Alzheimer's & Dementia. 10
Autor:
Kaitryn E. Ronning, Paul-Alexandre Déchelle-Marquet, Yueshen Che, Xavier Guillonneau, Florian Sennlaub, Cécile Delarasse
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 14, p 11747 (2023)
Alzheimer’s disease (AD) is a progressive neurodegenerative disease characterized by impaired episodic memory and two pathological lesions: amyloid plaques and neurofibrillary tangles. In AD, damaged neurons and the accumulation of amyloid β (Aβ)
Externí odkaz:
https://doaj.org/article/2e31027e27514b4cb9f4347208ce67b0
Autor:
Jean-Baptiste Conart, Guillaume Blot, Sébastien Augustin, Géraldine Millet-Puel, Christophe Roubeix, Fanny Beguier, Hugo Charles-Messance, Sara Touhami, José-Alain Sahel, Jean-Paul Berrod, Thierry Léveillard, Xavier Guillonneau, Cécile Delarasse, Florian Sennlaub
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-15 (2020)
Abstract Background Rhegmatogenous retinal detachment (RD) involving the macula is a major cause of visual impairment despite high surgical success rate, mainly because of cone death. RD causes the infiltration of activated immune cells, but it is no
Externí odkaz:
https://doaj.org/article/d3b70a8884584bef8296201e33f43b57
Publikováno v:
Journal of Neuroimmunology. 275:162
Human immunodeficiency virus type 1 (HIV-1) infects microglia and macrophages in the brain during seroconversion and eventually results in neuroinflammation and neurodegeneration in susceptible individuals. Inflammasomes are cytosolic protein complex
Autor:
Martin, Elodie, Amar, Majid, Youssef, Ihsen, Kanellopoulos, Jean, Fontaine, Bertrand, Delatour, Benoit, Cecile, Delarasse
Publikováno v:
In Journal of Neuroimmunology 15 October 2014 275(1-2):126-126
Autor:
Sophie Lavalette, Jean-Baptiste Conart, Sara Touhami, Christophe Roubeix, Marianne Houssier, Sébastien Augustin, William Raoul, Christophe Combadière, Maria Febbraio, Huy Ong, Sylvain Chemtob, José-Alain Sahel, Cécile Delarasse, Xavier Guillonneau, Florian Sennlaub
Publikováno v:
Frontiers in Immunology, Vol 10 (2020)
Background: CD36, a member of the class B scavenger receptor family, participates in Toll-like receptor signaling on mononuclear phagocytes (MP) and can promote sterile pathogenic inflammation. We here analyzed the effect of CD36 deficiency on retina
Externí odkaz:
https://doaj.org/article/64e88b19444c4408b242d6d725cc1cba