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pro vyhledávání: '"Cecile Bieri"'
Autor:
Cecile Bieri, Akori Esmel, Melalie Keita, Luc Calvin Owono Owono, Brice Dali, Eugene Megnassan, Stanislav Miertus, Vladimir Frecer
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 8, p 6916 (2023)
Cost-effective therapy of neglected and tropical diseases such as malaria requires everlasting drug discovery efforts due to the rapidly emerging drug resistance of the plasmodium parasite. We have carried out computational design of new inhibitors o
Externí odkaz:
https://doaj.org/article/911538bdf4a743fa8e8eccac0ceb914e
Autor:
Akori Esmel, Cecile Bieri, Eugene Megnassan, Vladimir Frecer, Stanislav Miertus, Melalie Keita
Publikováno v:
Medicinal chemistry (Shariqah (United Arab Emirates)). 8(5)
We have studied inhibition of Plasmodium falciparum lactate dehydrogenase (pfLDH) by dihydroxynaphthoic acid (DHNA) analogues derivatives of hemigossypol-sesquiterpene found in cottonseed known to exhibit antimalarial activity. Molecular models of pf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cdf951b25fa651fd983846106e0f2e9
https://pubmed.ncbi.nlm.nih.gov/22741776
https://pubmed.ncbi.nlm.nih.gov/22741776