Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Cecil R. Pace-Asciak"'
Furanoid F-Acid F6 Uniquely Induces NETosis Compared to C16 and C18 Fatty Acids in Human Neutrophils
Autor:
Bincy M. Paul, Yuan Fang Liu, Jassim M. Al-Hassan, Mohammad Afzal, Cecil R. Pace-Asciak, Divya Nair, Nades Palaniyar, Sosamma Oommen, Meraj A. Khan
Publikováno v:
Biomolecules, Vol 8, Iss 4, p 144 (2018)
Biomolecules
Volume 8
Issue 4
Biomolecules
Volume 8
Issue 4
Various biomolecules induce neutrophil extracellular trap (NET) formation or NETosis. However, the effect of fatty acids on NETosis has not been clearly established. In this study, we focused on the NETosis-inducing ability of several lipid molecules
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8062744a393aa60fb036b2b58b9e1f12
https://www.mdpi.com/2218-273X/8/4/144
https://www.mdpi.com/2218-273X/8/4/144
Autor:
Cecil R. Pace-Asciak, Nades Palaniyar, Sosamma Oommen, Bincy M. Paul, Yuan Fang Liu, Xiao Yan Wen, Meraj A. Khan, Jassim M. Al-Hassan, Rui Guan, Divya Nair, Peiying Yang, Mohammad Afzal
Publikováno v:
Cancers
Cancers, Vol 11, Iss 7, p 960 (2019)
Volume 11
Issue 7
Cancers, Vol 11, Iss 7, p 960 (2019)
Volume 11
Issue 7
Identifying novel anti-cancer drugs is important for devising better cancer treatment options. In a series of studies designed to identify novel therapeutic compounds, we recently showed that a C-20 fatty acid (12,15-epoxy-13,14-dimethyleicosa-12,14-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6051ca625515cefadd71e80447cfc85b
https://doi.org/10.3390/cancers11070960
https://doi.org/10.3390/cancers11070960
Publikováno v:
Prostaglandins & Other Lipid Mediators. 107:43-47
We report the effects of two anti-cancer drugs, PBT-4, an experimental antagonist to the pro-inflammatory hepoxilins, and Gleevec (STI-571), an anti-leukaemic drug, on eicosanoid tumour levels in immunodeficient mice (NU/NU) xenografted with the leuk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bdc0bd6a7485154a59f2b5b58f197cf
https://doi.org/10.1016/j.prostaglandins.2013.03.004
https://doi.org/10.1016/j.prostaglandins.2013.03.004
Cyclooxygenase-2 inhibition partially protects against 60% O2 -mediated lung injury in neonatal rats
Autor:
Cecil R. Pace-Asciak, Azhar Masood, Mandy Lau, A. Keith Tanswell, Robert P. Jankov, Rosetta Belcastro, Crystal Kantores, Man Yi, Jun Li
Publikováno v:
Pediatric Pulmonology. 49:991-1002
Summary Rationale Use of the anti-inflammatory agent dexamethasone in premature infants with bronchopulmonary dysplasia has been curtailed, and no alternative anti-inflammatory agents are approved for this use. Our objective was to use a neonatal rat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22ccf952b3a3bec24ac2fb56befc6bc9
https://doi.org/10.1002/ppul.22921
https://doi.org/10.1002/ppul.22921
Autor:
Viral Brahmbhatt, Cecil R. Pace-Asciak, Muriel Briand, Manuel Oliveira, Viktoria Bastic Schmid, Jalil Benyacoub, Nabil Bosco, Geneviève Perrisseau, Frédéric Destaillats
Publikováno v:
The Journal of Nutritional Biochemistry. 24:104-111
The immunoregulatory effects of dietary omega-3 fatty acids are still not fully characterized. The aim of this study was to determine whether dietary eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) intake limits intestinal ischemia-reperfu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6574cc9de468bf6a8ece13ad40c88707
https://doi.org/10.1016/j.jnutbio.2012.02.014
https://doi.org/10.1016/j.jnutbio.2012.02.014
Autor:
Cecil R. Pace-Asciak
Publikováno v:
British Journal of Pharmacology. 158:972-981
The hepoxilin pathway was discovered over two decades ago. Products in this pathway are derived through the 12S-lipoxygenase/hepoxilin synthase enzyme system and contain intrinsic biological activity. This activity relates to the reorganization of ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed940feb0b46be23894a1d8a10aadc78
https://doi.org/10.1111/j.1476-5381.2009.00168.x
https://doi.org/10.1111/j.1476-5381.2009.00168.x
Autor:
Cecil R. Pace-Asciak, Abdallah Gharib, Nicole Sarda, Isabelle Delton, Michel Lagarde, Denis Reynaud
Publikováno v:
Journal of Neurochemistry. 62:126-133
The present study was undertaken to investigate the possible formation of hepoxilin A3 in the rat pineal gland and to study the potential physiological role for this compound in this tissue. Incubation of homogenates of rat pineal glands with arachid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8bbd924771e56c4a82649cb0691f64d
https://doi.org/10.1046/j.1471-4159.1994.62010126.x
https://doi.org/10.1046/j.1471-4159.1994.62010126.x
Autor:
Denis Reynaud, Irina Monnard, Cecil R. Pace-Asciak, Katherine Macé, Christian Darimont, Florence Blancher, Patricia Leone, Olivier Aprikian
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 293:R2006-R2012
The role of arachidonic acid (AA) on the development of adipose tissue is still controversial since its metabolites, i.e., prostaglandins, can either stimulate or inhibit preadipocyte differentiation in vitro. In the present study, we evaluated the e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f79feff51f727977336598f8089d4bc8
https://doi.org/10.1152/ajpregu.00382.2007
https://doi.org/10.1152/ajpregu.00382.2007
Publikováno v:
Mediators of Inflammation, Vol 2015 (2015)
Mediators of Inflammation
Mediators of Inflammation
Pulmonary exacerbations in cystic fibrosis airways are accompanied by inflammation, neutrophilia, and mucous thickening. Cystic fibrosis sputum contains a large amount of uncleared DNA contributed by neutrophil extracellular trap (NET) formation from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::606e4a5ef948bc3b8c8f1d29b541735e
https://doaj.org/article/93e298e90b1c4148bd88b301c75e5f96
https://doaj.org/article/93e298e90b1c4148bd88b301c75e5f96
Novel Eicosanoid Pathways: The Discovery of Prostacyclin/6-keto Prostaglandin F1α and the Hepoxilins
Autor:
Cecil R. Pace-Asciak
Publikováno v:
Molecular Neurobiology. 32:019-026
This article reviews a lecture I was honored to present at the Leon Wolfe Symposium in Montreal on March 25, 2004. The lecture described my research career, which started with my interaction with Wolfe at the Montreal Neurological Institute as a post
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7aeb4ed1088177fde95f75b19e31b75d
https://doi.org/10.1385/mn:32:1:019
https://doi.org/10.1385/mn:32:1:019