Innate Immune Cytokine Profiling and Biomarker Identification for Outcome in Dengue Patients

Autor: Sai Pallavi Pradeep, Pooja Hoovina Venkatesh, Nageswar R. Manchala, Arjun Vayal Veedu, Rajani K. Basavaraju, Leela Selvasundari, Manikanta Ramakrishna, Yogitha Chandrakiran, Vishwanath Krishnamurthy, Shivaranjani Holigi, Tinku Thomas, Cecil R. Ross, Mary Dias, Vijaya Satchidanandam

Publikováno v: Frontiers in Immunology, Vol 12 (2021)

BackgroundEarly biomarkers of progression to severe dengue are urgently required to enable effective patient management and control treatment costs. Innate immune cells, which comprise the earliest responders to infection and along with the cytokines

Externí odkaz: https://doaj.org/article/1ff3d82063c64726986252712c4f13d5

Unveiling extended gamma-ray emission around HESS J1813-178

Autor: Aharonian, F., Benkhali, F. Ait, Aschersleben, J., Ashkar, H., Backes, M., Baktash, A., Martins, V. Barbosa, Barnard, J., Batzofin, R., Becherini, Y., Berge, D., Bernlöhr, K., Bi, B., Böttcher, M., Boisson, C., Bolmont, J., de Lavergne, M. de Bony, Borowska, J., Bouyahiaoui, M., Breuhaus, M., Brose, R., Brun, F., Bruno, B., Bulik, T., Burger-Scheidlin, C., Caroff, S., Casanova, S., Cecil, R., Celic, J., Cerruti, M., Chambery, P., Chand, T., Chen, A., Chibueze, J., Chibueze, O., Cotter, G., Mbarubucyeye, J. Damascene, Djannati-Ataï, A., Dmytriiev, A., Doroshenko, V., Einecke, S., Ernenwein, J. -P., Feijen, K., Filipovic, M., Fontaine, G., Füßling, M., Funk, S., Gabici, S., Gallant, Y. A., Ghafourizadeh, S., Giavitt, G., Glawion, D., Glicenstein, J. F., Goswami, P., Grolleron, G., Grondin, M. -H., Hinton, J. A., Hofmann, W., Holch, T. L., Holler, M., Jamrozy, M., Jankowsky, F., Joshi, V., Jung-Richardt, I., Katarzyński, K., Khatoon, R., Khélifi, B., Klepser, S., Kluźniak, W., Komin, Nu., Kosack, K., Kostunin, D., Kundu, A., Lang, R. G., Stum, S. Le, Leitl, F., Lemière, A., Lemoine-Goumard, M., Lenain, J. -P., Leuschner, F., Mackey, J., Malyshev, D., Marandon, V., Marinos, P., Martí-Devesa, G., Marx, R., Mehta, A., Mitchell, A., Moderski, R., Mohrmann, L., Montanari, A., Moulin, E., Murach, T., de Naurois, M., Niemiec, J., Noel, A. Priyana, O'Brien, P., Ohm, S., Olivera-Nieto, L., Wilhelmi, E. de Ona, Ostrowski, M., Panny, S., Panter, M., Parsons, R. D., Prokhorov, D. A., Pühlhofer, G., Punch, M., Quirrenbach, A., Regeard, M., Reichherzer, P., Reimer, A., Reimer, O., Ren, H., Renaud, M., Reville, B., Rieger, F., Roellinghoff, G., Rudak, B., Sahakian, V., Salzmann, H., Sasaki, M., Schüssler, F., Schutte, H. M., Shapopi, J. N. S., Specovius, A., Spencer, S., Steenkamp, R., Steinmassl, S., Steppa, C., Sushch, I., Suzuki, H., Takahashi, T., Tanaka, T., Terrier, R., Tluczykont, M., Tsuji, N., Unbehaun, T., van Eldik, C., Vecchi, M., Veh, J., Venter, C., Vink, J., Wach, T., Wagner, S. J., Wierzcholska, A., Zacharias, M., Zargaryan, D., Zdziarski, A. A., Zouari, S., Żywucka, N.

Publikováno v: A&A 686, A149 (2024)

HESS J1813$-$178 is a very-high-energy $\gamma$-ray source spatially coincident with the young and energetic pulsar PSR J1813$-$1749 and thought to be associated with its pulsar wind nebula (PWN). Recently, evidence for extended high-energy emission

Externí odkaz: http://arxiv.org/abs/2403.16802

Curvature in the very-high energy gamma-ray spectrum of M87

Autor: Collaboration, H. E. S. S., Aharonian, F., Benkhali, F. Ait, Aschersleben, J., Ashkar, H., Backes, M., Martins, V. Barbosa, Batzofin, R., Becherini, Y., Berge, D., Bernlöhr, K., Böttcher, M., Boisson, C., Bolmont, J., de Lavergne, M. de Bony, Bradascio, F., Brose, R., Brun, F., Bruno, B., Burger-Scheidlin, T. Bulik C., Bylund, T., Casanova, S., Cecil, R., Celic, J., Cerruti, M., Chand, T., Chandra, S., Chen, A., Chibueze, J., Chibueze, O., Collins, T., Cotter, G., Mbarubucyeye, J. Damascene, Djannati-Ataï, A., Djuvsland, J., Dmytriiev, A., Egberts, K., Einecke, S., Fegan, S., Fontaine, G., Funk, S., Gabici, S., Glicenstein, J. F., Glombitza, J., Grolleron, G., Haerer, L., Hofmann, W., Holch, T. L., Holler, M., Horns, D., Jamrozy, M., Jankowsky, F., Joshi, V., Jung-Richardt, I., Kasai, E., Katarzyński, K., Khatoon, R., Khélifi, B., Kluźniak, W., Komin, Nu., Kosack, K., Kostunin, D., Kundu, A., Lang, R. G., Stum, S. Le, Leitl, F., Lemière, A., Lemoine-Goumard, M., Lenain, J. -P., Lypova, I., Luashvili, A., Mackey, J., Malyshev, D., Martí-Devesa, G., Marx, R., Mehta, A., Meyer, M., Mitchell, A., Moderski, R., Moghadam, M. O., Mohrmann, L., Montanari, A., Moulin, E., Murach, T., de Naurois, M., Niemiec, J., Ohm, S., Olivera-Nieto, L., Wilhelmi, E. de Ona, Panny, S., Panter, M., Parsons, R. D., Pensec, U., Pita, S., Pühlhofer, G., Punch, M., Quirrenbach, A., Regeard, M., Reimer, A., Reimer, O., Ren, H., Reville, B., Rieger, F., Rudak, B., Ruiz-Velasco, E., Sahakian, V., Salzmann, H., Santangelo, A., Sasaki, M., Schüssler, F., Schutte, H. M., Shapopi, J. N. S., Sol, H., Spencer, S., Stawarz, Ł., Steenkamp, R., Steinmassl, S., Steppa, C., Streil, K., Takahashi, T., Tanaka, T., Taylor, A. M., Terrier, R., Tsirou, M., van Eldik, C., Venter, C., Vink, J., Wach, T., Wagner, S. J., Wierzcholska, A., Zacharias, M., Zdziarski, A. A., Zech, A., Zilberman, P., Zywucka, N.

Publikováno v: A&A, 685, A96 (2024)

The radio galaxy M87 is a variable very-high energy (VHE) gamma-ray source, exhibiting three major flares reported in 2005, 2008, and 2010. Despite extensive studies, the origin of the VHE gamma-ray emission is yet to be understood. In this study, we

Externí odkaz: http://arxiv.org/abs/2402.13330

Flap cover in a patient with severe haemophilia type A

Autor: Narender Manickavachakan, Sunderraj Ellur, Vijay Thomas Mattyoo Joseph, Jonathan Victor, Cecil R. Ross

Publikováno v: Indian Journal of Plastic Surgery, Vol 50, Iss 02, Pp 213-216 (2017)

Haemophilia A is a rare haematological disorder due to deficiency of Factor VIII, causing an abnormal coagulation response to injury. In severe haemophilia A, Factor VIII level is

Externí odkaz: https://doaj.org/article/41d8f9bbd43b4f0bbae98a0aae35f06c

Multiwavelength Observations of the Blazar PKS 0735+178 in Spatial and Temporal Coincidence with an Astrophysical Neutrino Candidate IceCube-211208A

Autor: Acharyya, A., Adams, C. B., Archer, A., Bangale, P., Bartkoske, J. T., Batista, P., Benbow, W., Brill, A., Buckley, J. H., Christiansen, J. L., Chromey, A. J., Errando, M., Falcone, A., Feng, Q., Foote, G. M., Fortson, L., Furniss, A., Gallagher, G., Hanlon, W., Hanna, D., Hervet, O., Hinrichs, C. E., Hoang, J., Holder, J., Humensky, T. B., Jin, W., Kaaret, P., Kertzman, M., Kherlakian, M., Kieda, D., Kleiner, T. K., Korzoun, N., Kumar, S., Lang, M. J., Lundy, M., Maier, G., McGrath, C. E, Millard, M. J., Millis, J., Mooney, C. L., Moriarty, P., Mukherjee, R., O'Brien, S., Ong, R. A., Pohl, M., Pueschel, E., Quinn, J., Ragan, K., Reynolds, P. T., Ribeiro, D., Roache, E., Sadeh, I., Sadun, A. C., Saha, L., Santander, M., Sembroski, G. H., Shang, R., Splettstoesser, M., Talluri, A. Kaushik, Tucci, J. V., Vassiliev, V. V., Weinstein, A., Williams, D. A., Wong, S. L., Woo, J., Aharonian, F., Aschersleben, J., Backes, M., Martins, V. Barbosa, Batzofin, R., Becherini, Y., Berge, D., Bernlohr, K., Bi, B., Bottcher, M., Boisson, C., Bolmont, J., de Lavergne, M. de Bony, Borowska, J., Bouyahiaoui, M., Bradascio, F., Breuhaus, M., Brose, R., Brun, F., Bruno, B., Bulik, T., Burger-Scheidlin, C., Caroff, S., Casanova, S., Cecil, R., Celic, J., Cerruti, M., Chand, T., Chandra, S., Chen, A., Chibueze, J., Chibueze, O., Cotter, G., Dai, S., Mbarubucyeye, J. Damascene, Djannati-Atai, A., Dmytriiev, A., Doroshenko, V., Einecke, S., Ernenwein, J. -P., de Clairfontaine, G. Fichet, Filipovic, M., Fontaine, G., Fussling, M., Funk, S., Gabici, S., Ghafourizadeh, S., Giavitto, G., Glawion, D., Glicenstein, J. F., Goswami, P., Grolleron, G., Haerer, L., Hinton, J. A., Holch, T. L., Holler, M., Horns, D., Jamrozy, M., Jankowsky, F., Joshi, V., Jung-Richardt, I., Kasai, E., Katarzynski, K., Khatoon, R., Khelifi, B., Klepser, S., Kluzniak, W., Kosack, K., Kostunin, D., Lang, R. G., Stum, S. Le, Lemiere, A., Lenain, J. P., Leuschner, F., Lohse, T., Luashvili, A., Lypova, I., Mackey, J., Malyshev, D., Marandon, V., Marchegiani, P., Marcowith, A., Marti-Devesa, G., Marx, R., Mitchell, A., Moderski, R., Mohrmann, L., Montanari, A., Moulin, E., Murach, T., Nakashima, K., Niemiec, J., Noel, A. Priyana, O'Brien, P., Olivera-Nieto, L., Wilhelmi, E. de Ona, Ostrowski, M., Panny, S., Panter, M., Peron, G., Prokhorov, D. A., Puhlhofer, G., Punch, M., Quirrenbach, A., Reichherzer, P., Reimer, A., Reimer, O., Ren, H., Renaud, M., Rieger, F., Rudak, B., Ruiz-Velasco, E., Sahakian, V., Santangelo, A., Sasaki, M., Schafer, J., Schussler, F., Schutte, H. M., Schwanke, U., Shapopi, J. N. S., Specovius, A., Spencer, S., Stawarz, L., Steenkamp, R., Steinmassl, S., Sushch, I., Suzuki, H., Takahashi, T., Tanaka, T., Terrier, R., van Eldik, C., Vecchi, M., Veh, J., Venter, C., Vink, J., White, R., Wierzcholska, A., Wong, Yu Wun, Zacharias, M., Zargaryan, D., Zdziarski, A. A., Zech, A., Zouari, S., Zywucka, N., Mori, K.

We report on multiwavelength target-of-opportunity observations of the blazar PKS 0735+178, located 2.2$^\circ$ away from the best-fit position of the IceCube neutrino event IceCube-211208A detected on December 8, 2021. The source was in a high-flux

Externí odkaz: http://arxiv.org/abs/2306.17819