Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Cecil J. Weale"'
Autor:
Dipuo D. Motshwari, Cindy George, Don M. Matshazi, Cecil J. Weale, Saarah F. G. Davids, Annalise E. Zemlin, Rajiv T. Erasmus, Andre P. Kengne, Tandi E. Matsha
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract The burden of chronic kidney disease (CKD) in Africa remains poorly characterized, due partly to the lack of appropriate diagnostic strategies. Although in recent years the diagnostic and prognostic utility of microRNAs (miRNAs) have gained
Externí odkaz:
https://doaj.org/article/2f09134b67304a3a8a00568bb1362cb5
Autor:
Cecil J. Weale, Don M. Matshazi, Saarah F. G. Davids, Shanel Raghubeer, Rajiv T. Erasmus, Andre P. Kengne, Glenda M. Davison, Tandi E. Matsha
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Aim: The influence of disease duration and anti-diabetic treatment on epigenetic processes has been described, with limited focus on interactions with microRNAs (miRNAs). miRNAs have been found to play key roles in the regulation of pathways associat
Externí odkaz:
https://doaj.org/article/9379b3e8f54f4bf597f7cfb184cd8158
Autor:
Don M. Matshazi, Cecil J. Weale, Rajiv T. Erasmus, Andre P. Kengne, Saarah F. G. Davids, Shanel Raghubeer, Glenda M. Davison, Tandi E. Matsha
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
MicroRNAs are non-coding, post-transcriptional regulators of gene expression and their dysregulation has been associated with development of various diseases, including hypertension. Consequently, understanding their role in the pathogenesis and prog
Externí odkaz:
https://doaj.org/article/2dfb007e921b4233948dca301a242b23
Autor:
Don M. Matshazi, Cecil J. Weale, Rajiv T. Erasmus, Andre P. Kengne, Saarah F. G. Davids, Shanel Raghubeer, Stanton Hector, Glenda M. Davison, Tandi E. Matsha
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Hypertension has a complex pathogenesis and symptoms appear in advanced disease. Dysregulation of gene expression regulatory factors like microRNAs has been reported in disease development. Identifying biomarkers which could help understand the patho
Externí odkaz:
https://doaj.org/article/f36ace27c13b41ac87f18b507fab83ac
Autor:
Dipuo D. Motshwari, Cindy George, Don M. Matshazi, Cecil J. Weale, Saarah F. G. Davids, Rajiv T. Erasmus, Andre P. Kengne, Tandi E. Matsha
Publikováno v:
Applied Sciences, Vol 11, Iss 16, p 7674 (2021)
The asymptomatic nature of and lack of effective early-stage diagnostic tools in CKD, predisposes individuals to the risk of end-stage CKD and related complications. Whole blood microRNAs (miRNAs) have the potential for CKD risk screening. We evaluat
Externí odkaz:
https://doaj.org/article/acbf995444164b9883246d3701dd017a
Autor:
Cecil J. Weale, Don M. Matshazi, Saarah F. G. Davids, Shanel Raghubeer, Rajiv T. Erasmus, Andre P. Kengne, Glenda M. Davison, Tandi E. Matsha
Publikováno v:
Diagnostics, Vol 11, Iss 6, p 949 (2021)
This cross-sectional study investigated the association of miR-1299, -126-3p and -30e-3p with and their diagnostic capability for dysglycaemia in 1273 (men, n = 345) South Africans, aged >20 years. Glycaemic status was assessed by oral glucose tolera
Externí odkaz:
https://doaj.org/article/0334ae5876444e069f74c91a88b55d81
Autor:
Cecil J Weale, Chanelle Schroeder, Don M Matshazi, Saarah FG Davids, Rajiv T Erasmus, Andre P Kengne, Glenda M Davison, Tandi E Matsha
Publikováno v:
Journal of Diabetes Investigation, Vol 15, Iss 10, Pp 1377-1389 (2024)
Abstract Aims This study aims to investigate miR‐486‐5p and miR‐novel‐chr1_40444 expressions in dysglycemic individuals. Validating RNA‐sequencing findings in a larger sample via reverse transcription qPCR (RT‐qPCR), we aim to address glo
Externí odkaz:
https://doaj.org/article/8f0a9dad6ef54bf5a056d5a747673762
Autor:
Cecil J. Weale, Glenda M. Davison, Gloudina M. Hon, Andre P. Kengne, Rajiv T. Erasmus, Tandi E. Matsha
Publikováno v:
Cells, Vol 8, Iss 5, p 464 (2019)
Telomeres are DNA-tandem repeats situated at the ends of chromosomes and are responsible for genome stabilization. They are eroded by increased cell division, age and oxidative stress with shortened leucocyte telomeres (LTL) being associated with inf
Externí odkaz:
https://doaj.org/article/c14feb412bdd445f88f7f391626ddbea
Autor:
Shanel Raghubeer, Don M. Matshazi, Dipuo D. Motshwari, Cecil J. Weale, Rajiv T. Erasmus, Tandi E. Matsha
Publikováno v:
Biomarkers in Diabetes ISBN: 9783031080135
Biomarkers in Diabetes ISBN: 9783030813031
Biomarkers in Diabetes ISBN: 9783030813031
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e06fdac1e8625ecb2e4108767d60392
https://doi.org/10.1007/978-3-031-08014-2_61
https://doi.org/10.1007/978-3-031-08014-2_61
Autor:
Tandi E. Matsha, Cecil J. Weale, Rajiv T Erasmus, Glenda M. Davison, Don M Matshazi, Shanel Raghubeer, Andre Pascal Kengne, Saarah F G Davids
Publikováno v:
Molecular Biology Reports
MicroRNAs are important in development of disease, and description of novel microRNAs adds to the pool of microRNAs that can be targeted for diagnostic and therapeutic purposes in disease. Herein, we aimed to describe novel microRNAs in a normotensiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cdfc52afe6f1d25c25cfbd9222db5c2
https://doi.org/10.1007/s11033-021-06304-1
https://doi.org/10.1007/s11033-021-06304-1