Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Cecele J. Denman"'
Autor:
Cecele J Denman, Vladimir V Senyukov, Srinivas S Somanchi, Prasad V Phatarpekar, Lisa M Kopp, Jennifer L Johnson, Harjeet Singh, Lenka Hurton, Sourindra N Maiti, M Helen Huls, Richard E Champlin, Laurence J N Cooper, Dean A Lee
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30264 (2012)
NK cells have therapeutic potential for a wide variety of human malignancies. However, because NK cells expand poorly in vitro, have limited life spans in vivo, and represent a small fraction of peripheral white blood cells, obtaining sufficient cell
Externí odkaz:
https://doaj.org/article/d590fb68bb70428792b653a2df2c3c92
Autor:
Richard E. Champlin, Dean A. Lee, Indreshpal Kaur, Gabriela Rondon, Dana Willis, Sairah Ahmed, Doris Soebbing, Jolie Schafer, Elizabeth J. Shpall, Alison M. Gulbis, Roland L. Bassett, Stefan O. Ciurea, Julianne Chen, Katayoun Rezvani, Cecele J. Denman, Kai Cao
Publikováno v:
Blood. 130:1857-1868
Relapse has emerged as the most important cause of treatment failure after allogeneic hematopoietic stem cell transplantation (HSCT). To test the hypothesis that natural killer (NK) cells can decrease the risk of leukemia relapse, we initiated a phas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f987f41da12dc0588e9dd7a28e47c47d
https://doi.org/10.1182/blood-2017-05-785659
https://doi.org/10.1182/blood-2017-05-785659
Autor:
Indreshpal Kaur, Elizabeth J. Shpall, Tobi Fisher, Gabriela Rondon, Marcelo Fernandez-Vina, Julianne Chen, Kai Cao, Dean A. Lee, Glenda Woodworth, Cecele J. Denman, Stefan O. Ciurea, Richard E. Champlin
Publikováno v:
Biology of Blood and Marrow Transplantation. 22:1290-1298
Allogeneic stem cell transplantation is an effective treatment for high-risk myeloid malignancies, but relapse remains the major post-transplantation cause of treatment failure. Alloreactive natural killer (NK) cells mediate a potent antileukemic eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ae26db05835f8ba6f236793257f9b38
https://doi.org/10.1016/j.bbmt.2016.04.009
https://doi.org/10.1016/j.bbmt.2016.04.009
Autor:
Cecele J. Denman, Shiguo Zhu, Dean A. Lee, Dennis P.M. Hughes, Eugenie S. Kleinerman, Ching C. Lau, Stephen Gottschalk, Zehra S. Cobanoglu, Simin Kiany
Publikováno v:
Pharmaceutical Research. 32:779-792
Natural killer (NK) cell cytotoxicity correlates with the ligation of activating receptors (e.g., NKG2D) by their ligands (e.g., MHC class I-related chains [MIC] A and B) on target cells. Histone deacetylase inhibitors (HDACi) at high concentrations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::987631462cf990b4e1aedeb643dd8a4f
https://doi.org/10.1007/s11095-013-1231-0
https://doi.org/10.1007/s11095-013-1231-0
Autor:
Cecele J. Denman, Jared Klarquist, Raymond E. Boissy, I. Caroline Le Poole, Kettil Cedercreutz, Rama Vaitla, Wiete Westerhof, Claudia Hernandez
Publikováno v:
Journal of the Dermatology Nurses' Association. 2:265-272
The disease pathway of the skin pigmentary disorder vitiligo involves hereditary factors, disease onset after overproduction of reactive oxygen species, and disease expansion through an adaptive, antigen-specific immune response to melanocytes. The c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18f401c4ebe41a8ea1e7e019add6c14c
https://doi.org/10.1097/jdn.0b013e3181fe9b33
https://doi.org/10.1097/jdn.0b013e3181fe9b33
Autor:
Jared Klarquist, Andreas Overbeck, Derek A. Wainwright, Faith M. Strickland, Cecele J. Denman, I. Caroline Le Poole, Michael I. Nishimura, Shikar Mehrotra, Claudia Hernandez
Publikováno v:
Pigment Cell & Melanoma Research. 23:276-286
In human vitiligo, cutaneous depigmentation involves cytotoxic activity of autoreactive T cells. It was hypothesized that depigmentation can progress in the absence of regulatory T cells (Treg). The percentage of Treg among skin infiltrating T cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7933c6bdbec792a856c8c9839cb6f27c
https://doi.org/10.1111/j.1755-148x.2010.00688.x
https://doi.org/10.1111/j.1755-148x.2010.00688.x
Autor:
Anne K. Bowlin, Roger G. Rank, Ira M. Sigar, Justin H. Schripsema, Garry A. S. Myers, Kyle H. Ramsey, Cecele J. Denman
Publikováno v:
Infection and Immunity. 77:3284-3293
The mouse chlamydial pathogen Chlamydia muridarum has been used as a model organism for the study of human Chlamydia trachomatis urogenital and respiratory tract infections. To date, two commonly used C. muridarum isolates have been used interchangea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f908e7356adedd85acb5f68dc7dde6b
https://doi.org/10.1128/iai.00147-09
https://doi.org/10.1128/iai.00147-09
Publikováno v:
Journal of the American Academy of Dermatology. 59:967-974
Background Condyloma acuminatum are common lesions caused by human papillomavirus (HPV). HPV is associated with many human cancers, and a vaccine now prevents infection with high-risk HPV. However, eradication of established disease is difficult, ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb7ee8d7c00e2c19b67ee12210bb79eb
https://doi.org/10.1016/j.jaad.2008.08.011
https://doi.org/10.1016/j.jaad.2008.08.011
Autor:
Vidhya Hariharan, José A. Guevara-Patiño, Cecele J. Denman, I. Caroline Le Poole, James McCracken, Kepa Oyarbide-Valencia, Jared Klarquist
Publikováno v:
Journal of Investigative Dermatology. 128(8):2041-2048
Vitiligo is a T-cell-mediated autoimmune disease of the skin. Progressive depigmentation accelerates in response to stress. Personal trauma, contact with bleaching phenols, overexposure to UV, and mechanical injury can lead to progressive loss of mel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93019898ac2ef630f55eeeb58527f384
Autor:
Srinivas S. Somanchi, Jordan S. Orange, Dean A. Lee, Hoainam Nguyen-Jackson, Alexandra F. Freeman, Vladimir Senyukov, Steven M. Holland, Stephanie S. Watowich, Emily M. Mace, Cecele J. Denman, Shiguo Zhu, Prasad V. Phatarpekar
Signal transducer and activator of transcription 3 (STAT3) is considered a negative regulator of inflammation, as inhibition of STAT3 signaling enhances antitumor immunity. However, STAT3 activation is a key oncogenic pathway in natural killer (NK)-l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e8aefade1a8b52f2af9ebfa92201a52
https://europepmc.org/articles/PMC4102712/
https://europepmc.org/articles/PMC4102712/
