Zobrazeno 1 - 10 of 69 pro vyhledávání: '"Cecconie T"'
1
Akademický článek
Biochemical and functional characterization of the p.A165T missense variant of mitochondrial amidoxime-reducing component 1.
Autor: Hou W; Respiratory and Immunology Biology Unit, GlaxoSmithKline, Collegeville, Pennsylvania, USA., Watson C; Respiratory and Immunology Biology Unit, GlaxoSmithKline, Collegeville, Pennsylvania, USA., Cecconie T; MEDDesign-NCE-MD SPMB US, GlaxoSmithKline, Collegeville, Pennsylvania, USA., Bolaki MN; 23andMe Therapeutics, Sunnyvale, California, USA., Brady JJ; 23andMe Therapeutics, Sunnyvale, California, USA., Lu Q; Respiratory and Immunology Biology Unit, GlaxoSmithKline, Collegeville, Pennsylvania, USA., Gatto GJ Jr; Respiratory and Immunology Biology Unit, GlaxoSmithKline, Collegeville, Pennsylvania, USA. Electronic address: greg.j.gatto@gsk.com., Day TA; Department of Biology, Northeastern University, Boston, Massachusetts, USA.
Publikováno v: The Journal of biological chemistry [J Biol Chem] 2024 Jun; Vol. 300 (6), pp. 107353. Date of Electronic Publication: 2024 May 07.
Zobrazit plný text záznamu
2
Akademický článek
Discovery and SAR Study of Boronic Acid-Based Selective PDE3B Inhibitors from a Novel DNA-Encoded Library.
Autor: Rowley AM; GSK, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, United States., Yao G; GSK, Encoded Library Technologies, NCE Molecular Discovery, 200 Cambridge Park Drive, Cambridge, Massachusetts 02140, United States., Andrews L; 23andMe Inc, Therapeutics, 349 Oyster Point Boulevard, South San Francisco, California 94080, United States., Bedermann A; GSK, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, United States., Biddulph R; GSK Medicines Research Centre, Gunnels Wood Road, Stevenage SG1 2NY, Hertfordshire, U.K., Bingham R; GSK Medicines Research Centre, Gunnels Wood Road, Stevenage SG1 2NY, Hertfordshire, U.K., Brady JJ; 23andMe Inc, Therapeutics, 349 Oyster Point Boulevard, South San Francisco, California 94080, United States., Buxton R; GSK Medicines Research Centre, Gunnels Wood Road, Stevenage SG1 2NY, Hertfordshire, U.K., Cecconie T; GSK, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, United States., Cooper R; GSK, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, United States., Csakai A; GSK, Encoded Library Technologies, NCE Molecular Discovery, 200 Cambridge Park Drive, Cambridge, Massachusetts 02140, United States., Gao EN; GSK, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, United States., Grenier-Davies MC; GSK, Encoded Library Technologies, NCE Molecular Discovery, 200 Cambridge Park Drive, Cambridge, Massachusetts 02140, United States., Lawler M; GSK, Encoded Library Technologies, NCE Molecular Discovery, 200 Cambridge Park Drive, Cambridge, Massachusetts 02140, United States., Lian Y; GSK, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, United States., Macina J; GSK Medicines Research Centre, Gunnels Wood Road, Stevenage SG1 2NY, Hertfordshire, U.K., Macphee C; GSK Medicines Research Centre, Gunnels Wood Road, Stevenage SG1 2NY, Hertfordshire, U.K., Marcaurelle L; GSK, Encoded Library Technologies, NCE Molecular Discovery, 200 Cambridge Park Drive, Cambridge, Massachusetts 02140, United States., Martin J; GSK, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, United States., McCormick P; GSK, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, United States., Pindoria R; GSK Medicines Research Centre, Gunnels Wood Road, Stevenage SG1 2NY, Hertfordshire, U.K., Rauch M; GSK, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, United States., Rocque W; GSK, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, United States., Shen Y; GSK, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, United States., Shewchuk LM; GSK, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, United States., Squire M; GSK, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, United States., Stebbeds W; GSK Medicines Research Centre, Gunnels Wood Road, Stevenage SG1 2NY, Hertfordshire, U.K., Tear W; GSK, Encoded Library Technologies, NCE Molecular Discovery, 200 Cambridge Park Drive, Cambridge, Massachusetts 02140, United States., Wang X; 23andMe Inc, Therapeutics, 349 Oyster Point Boulevard, South San Francisco, California 94080, United States., Ward P; GSK, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, United States., Xiao S; 23andMe Inc, Therapeutics, 349 Oyster Point Boulevard, South San Francisco, California 94080, United States.
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2024 Feb 08; Vol. 67 (3), pp. 2049-2065. Date of Electronic Publication: 2024 Jan 29.
Zobrazit plný text záznamu
3
Akademický článek
Discovery of Proline-Based p300/CBP Inhibitors Using DNA-Encoded Library Technology in Combination with High-Throughput Screening.
Autor: Tian X; Research and Development, GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, United States., Suarez D; Research and Development, GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, United States., Thomson D; Cellzome GmbH, A GlaxoSmithKline Company, Meyerhofstrasse 1, 69117 Heidelberg, Germany., Li W; Research and Development, GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, United States., King EA; Research and Development, GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, United States., LaFrance L; Research and Development, GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, United States., Boehm J; Research and Development, GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, United States., Barton L; Research and Development, GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, United States., Di Marco C; Research and Development, GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, United States., Martyr C; Research and Development, GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, United States., Thalji R; Research and Development, GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, United States., Medina J; Research and Development, GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, United States., Knight S; Research and Development, GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, United States., Heerding D; Research and Development, GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, United States., Gao E; Research and Development, GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, United States., Nartey E; Research and Development, GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, United States., Cecconie T; Research and Development, GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, United States., Nixon C; Research and Development, GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, United States., Zhang G; Research and Development, GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, United States., Berrodin TJ; Research and Development, GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, United States., Phelps C; New Chemical Entity Molecular Discovery, GlaxoSmithKline, 200 Cambridgepark Drive, Cambridge, Massachusetts 02140, United States., Patel A; New Chemical Entity Molecular Discovery, GlaxoSmithKline, 200 Cambridgepark Drive, Cambridge, Massachusetts 02140, United States., Bai X; New Chemical Entity Molecular Discovery, GlaxoSmithKline, 200 Cambridgepark Drive, Cambridge, Massachusetts 02140, United States., Lind K; New Chemical Entity Molecular Discovery, GlaxoSmithKline, 200 Cambridgepark Drive, Cambridge, Massachusetts 02140, United States., Prabhu N; New Chemical Entity Molecular Discovery, GlaxoSmithKline, 200 Cambridgepark Drive, Cambridge, Massachusetts 02140, United States., Messer J; New Chemical Entity Molecular Discovery, GlaxoSmithKline, 200 Cambridgepark Drive, Cambridge, Massachusetts 02140, United States., Zhu Z; New Chemical Entity Molecular Discovery, GlaxoSmithKline, 200 Cambridgepark Drive, Cambridge, Massachusetts 02140, United States., Shewchuk L; Research and Development, GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, United States., Reid R; Research and Development, GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, United States., Graves AP; Research and Development, GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, United States., McHugh C; Research and Development, GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, United States., Mangatt B; Research and Development, GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, United States.
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2022 Nov 10; Vol. 65 (21), pp. 14391-14408. Date of Electronic Publication: 2022 Oct 27.
Zobrazit plný text záznamu
4
Akademický článek
Targeting the Regulatory Site of ER Aminopeptidase 1 Leads to the Discovery of a Natural Product Modulator of Antigen Presentation.
Autor: Liddle J; Discovery Partnerships with Academia, GlaxoSmithKline, Stevenage, Hertfordshire SG1 2NY, U.K., Hutchinson JP; Medicinal Science and Technology, GlaxoSmithKline, Stevenage, Hertfordshire SG1 2NY, U.K., Kitchen S; Discovery Partnerships with Academia, GlaxoSmithKline, Stevenage, Hertfordshire SG1 2NY, U.K., Rowland P; Medicinal Science and Technology, GlaxoSmithKline, Stevenage, Hertfordshire SG1 2NY, U.K., Neu M; Medicinal Science and Technology, GlaxoSmithKline, Stevenage, Hertfordshire SG1 2NY, U.K., Cecconie T; Medicinal Science and Technology, GlaxoSmithKline, Collegeville, Pennsylvania 19426, United States., Holmes DS; Discovery Partnerships with Academia, GlaxoSmithKline, Stevenage, Hertfordshire SG1 2NY, U.K., Jones E; Medicinal Science and Technology, GlaxoSmithKline, Stevenage, Hertfordshire SG1 2NY, U.K., Korczynska J; Medicinal Science and Technology, GlaxoSmithKline, Stevenage, Hertfordshire SG1 2NY, U.K., Koumantou D; National Centre for Scientific Research 'Demokritos', Patriarchou Gregoriou and Neapoleos 27, Agia Paraskevi, Athens 15341, Greece., Lea JD; Medicinal Science and Technology, GlaxoSmithKline, Stevenage, Hertfordshire SG1 2NY, U.K., Nickels L; Medicinal Science and Technology, GlaxoSmithKline, Collegeville, Pennsylvania 19426, United States., Pemberton M; Medicinal Science and Technology, GlaxoSmithKline, Stevenage, Hertfordshire SG1 2NY, U.K., Phillipou A; Medicinal Science and Technology, GlaxoSmithKline, Stevenage, Hertfordshire SG1 2NY, U.K., Schneck JL; Medicinal Science and Technology, GlaxoSmithKline, Collegeville, Pennsylvania 19426, United States., Sheehan H; Medicinal Science and Technology, GlaxoSmithKline, Stevenage, Hertfordshire SG1 2NY, U.K., Tinworth CP; Medicinal Science and Technology, GlaxoSmithKline, Stevenage, Hertfordshire SG1 2NY, U.K., Uings I; Discovery Partnerships with Academia, GlaxoSmithKline, Stevenage, Hertfordshire SG1 2NY, U.K., Wojno-Picon J; Medicinal Science and Technology, GlaxoSmithKline, Stevenage, Hertfordshire SG1 2NY, U.K., Young RJ; Medicinal Science and Technology, GlaxoSmithKline, Stevenage, Hertfordshire SG1 2NY, U.K., Stratikos E; National Centre for Scientific Research 'Demokritos', Patriarchou Gregoriou and Neapoleos 27, Agia Paraskevi, Athens 15341, Greece.
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2020 Mar 26; Vol. 63 (6), pp. 3348-3358. Date of Electronic Publication: 2020 Mar 09.
Zobrazit plný text záznamu
5
Conference
Quantitative Chemical Analysis using DVDs and Conventional Computer Optical Disk Drives.
Autor: Potyrailo, R.A., Morris, W.G., Leach, A.M., Sivavec, T.M., Hassib, L., Krishnan, K., Surman, C., Wroczynski, R., Boyette, S., Xiao, C., Agree, A., Cecconie, T.
Publikováno v: TRANSDUCERS 2007 - 2007 International Solid-State Sensors, Actuators & Microsystems Conference; 2007, p1115-1118, 4p
Zobrazit plný text záznamu
6
Akademický článek
Discovery of a Novel 2,6-Disubstituted Glucosamine Series of Potent and Selective Hexokinase 2 Inhibitors.
Autor: Lin H; Cancer Metabolism Chemistry; Cancer Metabolism Biology; and Platform Technology & Sciences, GlaxoSmithKline , 1250 South Collegeville Road, Collegeville, Pennsylvania 19426-0989, United States., Zeng J; Cancer Metabolism Chemistry; Cancer Metabolism Biology; and Platform Technology & Sciences, GlaxoSmithKline , 1250 South Collegeville Road, Collegeville, Pennsylvania 19426-0989, United States., Xie R; Cancer Metabolism Chemistry; Cancer Metabolism Biology; and Platform Technology & Sciences, GlaxoSmithKline , 1250 South Collegeville Road, Collegeville, Pennsylvania 19426-0989, United States., Schulz MJ; Cancer Metabolism Chemistry; Cancer Metabolism Biology; and Platform Technology & Sciences, GlaxoSmithKline , 1250 South Collegeville Road, Collegeville, Pennsylvania 19426-0989, United States., Tedesco R; Cancer Metabolism Chemistry; Cancer Metabolism Biology; and Platform Technology & Sciences, GlaxoSmithKline , 1250 South Collegeville Road, Collegeville, Pennsylvania 19426-0989, United States., Qu J; Cancer Metabolism Chemistry; Cancer Metabolism Biology; and Platform Technology & Sciences, GlaxoSmithKline , 1250 South Collegeville Road, Collegeville, Pennsylvania 19426-0989, United States., Erhard KF; Cancer Metabolism Chemistry; Cancer Metabolism Biology; and Platform Technology & Sciences, GlaxoSmithKline , 1250 South Collegeville Road, Collegeville, Pennsylvania 19426-0989, United States., Mack JF; Cancer Metabolism Chemistry; Cancer Metabolism Biology; and Platform Technology & Sciences, GlaxoSmithKline , 1250 South Collegeville Road, Collegeville, Pennsylvania 19426-0989, United States., Raha K; Cancer Metabolism Chemistry; Cancer Metabolism Biology; and Platform Technology & Sciences, GlaxoSmithKline , 1250 South Collegeville Road, Collegeville, Pennsylvania 19426-0989, United States., Rendina AR; Cancer Metabolism Chemistry; Cancer Metabolism Biology; and Platform Technology & Sciences, GlaxoSmithKline , 1250 South Collegeville Road, Collegeville, Pennsylvania 19426-0989, United States., Szewczuk LM; Cancer Metabolism Chemistry; Cancer Metabolism Biology; and Platform Technology & Sciences, GlaxoSmithKline , 1250 South Collegeville Road, Collegeville, Pennsylvania 19426-0989, United States., Kratz PM; Cancer Metabolism Chemistry; Cancer Metabolism Biology; and Platform Technology & Sciences, GlaxoSmithKline , 1250 South Collegeville Road, Collegeville, Pennsylvania 19426-0989, United States., Jurewicz AJ; Cancer Metabolism Chemistry; Cancer Metabolism Biology; and Platform Technology & Sciences, GlaxoSmithKline , 1250 South Collegeville Road, Collegeville, Pennsylvania 19426-0989, United States., Cecconie T; Cancer Metabolism Chemistry; Cancer Metabolism Biology; and Platform Technology & Sciences, GlaxoSmithKline , 1250 South Collegeville Road, Collegeville, Pennsylvania 19426-0989, United States., Martens S; Cancer Metabolism Chemistry; Cancer Metabolism Biology; and Platform Technology & Sciences, GlaxoSmithKline , 1250 South Collegeville Road, Collegeville, Pennsylvania 19426-0989, United States., McDevitt PJ; Cancer Metabolism Chemistry; Cancer Metabolism Biology; and Platform Technology & Sciences, GlaxoSmithKline , 1250 South Collegeville Road, Collegeville, Pennsylvania 19426-0989, United States., Martin JD; Cancer Metabolism Chemistry; Cancer Metabolism Biology; and Platform Technology & Sciences, GlaxoSmithKline , 1250 South Collegeville Road, Collegeville, Pennsylvania 19426-0989, United States., Chen SB; Cancer Metabolism Chemistry; Cancer Metabolism Biology; and Platform Technology & Sciences, GlaxoSmithKline , 1250 South Collegeville Road, Collegeville, Pennsylvania 19426-0989, United States., Jiang Y; Cancer Metabolism Chemistry; Cancer Metabolism Biology; and Platform Technology & Sciences, GlaxoSmithKline , 1250 South Collegeville Road, Collegeville, Pennsylvania 19426-0989, United States., Nickels L; Cancer Metabolism Chemistry; Cancer Metabolism Biology; and Platform Technology & Sciences, GlaxoSmithKline , 1250 South Collegeville Road, Collegeville, Pennsylvania 19426-0989, United States., Schwartz BJ; Cancer Metabolism Chemistry; Cancer Metabolism Biology; and Platform Technology & Sciences, GlaxoSmithKline , 1250 South Collegeville Road, Collegeville, Pennsylvania 19426-0989, United States., Smallwood A; Cancer Metabolism Chemistry; Cancer Metabolism Biology; and Platform Technology & Sciences, GlaxoSmithKline , 1250 South Collegeville Road, Collegeville, Pennsylvania 19426-0989, United States., Zhao B; Cancer Metabolism Chemistry; Cancer Metabolism Biology; and Platform Technology & Sciences, GlaxoSmithKline , 1250 South Collegeville Road, Collegeville, Pennsylvania 19426-0989, United States., Campobasso N; Cancer Metabolism Chemistry; Cancer Metabolism Biology; and Platform Technology & Sciences, GlaxoSmithKline , 1250 South Collegeville Road, Collegeville, Pennsylvania 19426-0989, United States., Qian Y; Cancer Metabolism Chemistry; Cancer Metabolism Biology; and Platform Technology & Sciences, GlaxoSmithKline , 1250 South Collegeville Road, Collegeville, Pennsylvania 19426-0989, United States., Briand J; Cancer Metabolism Chemistry; Cancer Metabolism Biology; and Platform Technology & Sciences, GlaxoSmithKline , 1250 South Collegeville Road, Collegeville, Pennsylvania 19426-0989, United States., Rominger CM; Cancer Metabolism Chemistry; Cancer Metabolism Biology; and Platform Technology & Sciences, GlaxoSmithKline , 1250 South Collegeville Road, Collegeville, Pennsylvania 19426-0989, United States., Oleykowski C; Cancer Metabolism Chemistry; Cancer Metabolism Biology; and Platform Technology & Sciences, GlaxoSmithKline , 1250 South Collegeville Road, Collegeville, Pennsylvania 19426-0989, United States., Hardwicke MA; Cancer Metabolism Chemistry; Cancer Metabolism Biology; and Platform Technology & Sciences, GlaxoSmithKline , 1250 South Collegeville Road, Collegeville, Pennsylvania 19426-0989, United States., Luengo JI; Cancer Metabolism Chemistry; Cancer Metabolism Biology; and Platform Technology & Sciences, GlaxoSmithKline , 1250 South Collegeville Road, Collegeville, Pennsylvania 19426-0989, United States.
Publikováno v: ACS medicinal chemistry letters [ACS Med Chem Lett] 2015 Dec 28; Vol. 7 (3), pp. 217-22. Date of Electronic Publication: 2015 Dec 28 (Print Publication: 2016).
Zobrazit plný text záznamu
9
Akademický článek
Theory and practice of ubiquitous quantitative chemical analysis using conventional computer optical disk drives.
Autor: Potyrailo RA; General Electric Company, Global Research Center, Niskayuna, NY 12309, USA. Potyrailo@crd.ge.com, Morris WG, Leach AM, Hassib L, Krishnan K, Surman C, Wroczynski R, Boyette S, Xiao C, Shrikhande P, Agree A, Cecconie T
Publikováno v: Applied optics [Appl Opt] 2007 Oct 01; Vol. 46 (28), pp. 7007-17.
Zobrazit plný text záznamu
10
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje