In Vitro and In Vivo Evaluation of Pellotine: A Hypnotic Lophophora Alkaloid.

Autor: Poulie CBM; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Jagtvej 160, 2100 Copenhagen, Denmark., Chan CB; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Jagtvej 160, 2100 Copenhagen, Denmark., Parka A; Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, C Universitetsparken 2, 2100 Copenhagen, Denmark., Lettorp M; Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, C Universitetsparken 2, 2100 Copenhagen, Denmark., Vos J; Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, C Universitetsparken 2, 2100 Copenhagen, Denmark., Raaschou A; Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, C Universitetsparken 2, 2100 Copenhagen, Denmark., Pottie E; Laboratory of Toxicology, Department of Bioanalysis, Faculty of Pharmaceutical Sciences, Ghent University, Campus Heymans, Ottergemsesteenweg 460, B-9000 Ghent, Belgium., Bundgaard MS; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Jagtvej 160, 2100 Copenhagen, Denmark., Sørensen LME; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Jagtvej 160, 2100 Copenhagen, Denmark., Cecchi CR; Translational Neuropsychiatry Unit, Department of Clinical Medicine, Aarhus University, Palle Juul-Jensens Boulevard 11, 8200 Aarhus N Aarhus, Denmark., Märcher-Rørsted E; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Jagtvej 160, 2100 Copenhagen, Denmark., Bach A; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Jagtvej 160, 2100 Copenhagen, Denmark., Herth MM; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Jagtvej 160, 2100 Copenhagen, Denmark.; Department of Clinical Physiology, Nuclear Medicine & PET, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen, Denmark., Decker A; Center for Drug Discovery, RTI International, Research Triangle Park, North Carolina 27709, United States., Jensen AA; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Jagtvej 160, 2100 Copenhagen, Denmark., Elfving B; Translational Neuropsychiatry Unit, Department of Clinical Medicine, Aarhus University, Palle Juul-Jensens Boulevard 11, 8200 Aarhus N Aarhus, Denmark., Kretschmann AC; Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, C Universitetsparken 2, 2100 Copenhagen, Denmark., Stove CP; Laboratory of Toxicology, Department of Bioanalysis, Faculty of Pharmaceutical Sciences, Ghent University, Campus Heymans, Ottergemsesteenweg 460, B-9000 Ghent, Belgium., Kohlmeier KA; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Jagtvej 160, 2100 Copenhagen, Denmark., Cornett C; Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, C Universitetsparken 2, 2100 Copenhagen, Denmark., Janfelt C; Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, C Universitetsparken 2, 2100 Copenhagen, Denmark., Kornum BR; Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, C Universitetsparken 2, 2100 Copenhagen, Denmark., Kristensen JL; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Jagtvej 160, 2100 Copenhagen, Denmark.

Publikováno v: ACS pharmacology & translational science [ACS Pharmacol Transl Sci] 2023 Sep 18; Vol. 6 (10), pp. 1492-1507. Date of Electronic Publication: 2023 Sep 18 (Print Publication: 2023).

Efficient Knockdown and Lack of Passenger Strand Activity by Dicer-Independent shRNAs Expressed from Pol II-Driven MicroRNA Scaffolds.

Autor: Kaadt E; Department of Biomedicine, Aarhus University, 8000 Aarhus C, Denmark., Alsing S; Department of Biomedicine, Aarhus University, 8000 Aarhus C, Denmark., Cecchi CR; Department of Biomedicine, Aarhus University, 8000 Aarhus C, Denmark., Damgaard CK; Department of Molecular Biology and Genetics, Aarhus University, 8000 Aarhus C, Denmark., Corydon TJ; Department of Biomedicine, Aarhus University, 8000 Aarhus C, Denmark; Department of Ophthalmology, Aarhus University Hospital, 8000 Aarhus C, Denmark., Aagaard L; Department of Biomedicine, Aarhus University, 8000 Aarhus C, Denmark. Electronic address: aagaard@biomed.au.dk.

Publikováno v: Molecular therapy. Nucleic acids [Mol Ther Nucleic Acids] 2019 Mar 01; Vol. 14, pp. 318-328. Date of Electronic Publication: 2018 Dec 01.

Efficient Non-Invasive Plasmid-DNA Administration into Tibialis Cranialis Muscle of "Little" Mice.

Autor: Cecchi CR; Biotechnology Center, Instituto de Pesquisas Energeticas e Nucleares (IPEN-CNEN), Av. Prof. Lineu Prestes 2242, 05508-000, Sao Paulo, SP. Brazil., Higuti E; Biotechnology Center, Instituto de Pesquisas Energeticas e Nucleares (IPEN-CNEN), Cidade Universitaria, Sao Paulo, SP. Brazil., Lima ER; Biotechnology Center, Instituto de Pesquisas Energeticas e Nucleares (IPEN-CNEN), Cidade Universitaria, Sao Paulo, SP. Brazil., Vieira DP; Biotechnology Center, Instituto de Pesquisas Energeticas e Nucleares (IPEN-CNEN), Cidade Universitaria, Sao Paulo, SP. Brazil., Squair PL; Radiopharmacy Center, Instituto de Pesquisas/ Energeticas e Nucleares (IPENCNEN), Cidade Universitaria, Sao Paulo, SP. Brazil., Peroni CN; Biotechnology Center, Instituto de Pesquisas Energeticas e Nucleares (IPEN-CNEN), Cidade Universitaria, Sao Paulo, SP. Brazil., Bartolini P; Biotechnology Center, Instituto de Pesquisas Energeticas e Nucleares (IPEN-CNEN), Cidade Universitaria, Sao Paulo, SP. Brazil.

Publikováno v: Current molecular medicine [Curr Mol Med] 2017; Vol. 17 (3), pp. 230-235.

Restoration of Haemoglobin Level Using Hydrodynamic Gene Therapy with Erythropoietin Does Not Alleviate the Disease Progression in an Anaemic Mouse Model for TGFβ1-Induced Chronic Kidney Disease.

Autor: Pedersen L; Research Laboratory for Biochemical Pathology, Aarhus University Hospital, Institute of Clinical Medicine, Aarhus, Denmark., Wogensen L; Research Laboratory for Biochemical Pathology, Aarhus University Hospital, Institute of Clinical Medicine, Aarhus, Denmark., Marcussen N; Department of Pathology, Odense University Hospital, Odense, Denmark., Cecchi CR; Department of Biomedicine, Aarhus University, Aarhus, Denmark., Dalsgaard T; Department of Biomedicine, Aarhus University, Aarhus, Denmark., Dagnæs-Hansen F; Department of Biomedicine, Aarhus University, Aarhus, Denmark.

Publikováno v: PloS one [PLoS One] 2015 Jun 05; Vol. 10 (6), pp. e0128367. Date of Electronic Publication: 2015 Jun 05 (Print Publication: 2015).

Growth responses following a single intra-muscular hGH plasmid administration compared to daily injections of hGH in dwarf mice.

Autor: Higuti E; Biotechnology Department, National Nuclear Energy Commission (IPEN-CNEN), Cidade Universitaria, São Paulo, SP, Brazil., Cecchi CR, Oliveira NA, Vieira DP, Jensen TG, Jorge AA, Bartolini P, Peroni CN

Publikováno v: Current gene therapy [Curr Gene Ther] 2012 Dec; Vol. 12 (6), pp. 437-43.