Výsledky vyhledávání - "Cecília Patrícia Popolin"

Structure Elucidation and Absolute Configuration Determination of Nortriterpenoids from Picramnia glazioviana

Autor: Fernando M. dos Santos, Leila Gimenes, Liany Luna-Dulcey, João M. Batista, Cecília Patrícia Popolin, João B. Fernandes, Márcia Regina Cominetti, Dan Staerk

Publikováno v: Journal of Natural Products. 83:1859-1875

In this study, HPLC-PDA-HRMS-SPE-NMR data were used for initial analysis of the CH2Cl2 fraction of an EtOH extract of the leaves of Picramnia glazioviana. The HRMS, UV, and NMR data obtained from the HPLC-PDA-HRMS-SPE-NMR analysis were used to direct

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6fcfdf011c0d2ac7084ebf130f0289ab
https://doi.org/10.1021/acs.jnatprod.0c00045

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Acetylation of cedrelone increases its cytotoxic activity and reverts the malignant phenotype of breast cancer cells in 3D culture

Autor: Angelina M. Fuzer, Vanessa de Cássia Domingues, Márcia Regina Cominetti, Cecília Patrícia Popolin, Cristiane de Melo Cazal, Paulo C. Vieira, Amanda Blanque Becceneri, João B. Fernandes

Publikováno v: Chemico-biological interactions. 316

Cedrelone is a limonoid isolated from the plant Trichilia catigua (Meliaceae). Previous studies have demonstrated that cedrelone (1) has several damaging effects on triple negative breast tumor (TNBC) cell line MDA-MB-231. In this work we investigate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::224b9493e7c14303ecb35290f25b757d
https://pubmed.ncbi.nlm.nih.gov/31857088

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The trans-[Ru(PPh3)2(N,N-dimethyl-N′-thiophenylthioureato-k2O,S)(bipy)] PF6 complex has pro-apoptotic effects on triple negative breast cancer cells and presents low toxicity in vivo

Autor: Eduardo E. Castellano, Cecília Patrícia Popolin, Alzir A. Batista, Ana M. Plutín, Edson Luis Maistro, Márcia Regina Cominetti, Amanda Blanque Becceneri

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Web of Science
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP

Made available in DSpace on 2018-11-26T17:54:53Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-09-01 Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Triple negative breast cancer (TNBC) is a heterogeneous subtype of breast t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d869e66cb4534ba96ea05efdc5af98ae

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A Review of Ruthenium Complexes Activities on Breast Cancer Cells

Autor: Cecília Patrícia Popolin, Márcia Regina Cominetti

Publikováno v: Mini reviews in medicinal chemistry. 17(15)

Background Cancer is one of the main causes of death worldwide. Breast cancer is the most prevalent type of cancer in women and the leading cause of cancer deaths due to its high metastasis to the lymph nodes, lungs bones and brain. Interactions with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f68fc3be5e82adf0be86d2a4b89c89f9
https://pubmed.ncbi.nlm.nih.gov/28176627

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Abstract A16: Evaluation of the genotoxicity of ruthenium complex, trans-[Ru(ThySMet)(PPh3)2(bipy)]PF6, by comet assay in vitro on breast cells and in vivo

Autor: Ana M. Plutín, Edson Luis Maistro, Amanda Blanque Becceneri, Alzir A. Batista, Cecília Patrícia Popolin, Márcia Regina Cominetti

Publikováno v: Molecular Cancer Research. 16:A16-A16

Cancer remains a major public health problem, accounting for one in six deaths worldwide. One of the most common types of cancer in women is breast cancer, which is extremely heterogeneous and composed of different subtypes. The majority of drugs cur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d6520ba17d0b2b7e952b259ea053787f
https://doi.org/10.1158/1557-3125.advbc17-a16

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Abstract A71: Evaluation of ruthenium complex [Ru(AmSal)(dppe)2]PF6 on the proliferation, morphology, and migration of triple-negative MDA-MB-231 breast tumor cells

Autor: Márcia Regina Cominetti, Angelica E. Graminha, Cecília Patrícia Popolin, Alzir A. Batista, Amanda Blanque Becceneri

Publikováno v: Molecular Cancer Research. 16:A71-A71

Breast cancer is the most prevalent type of cancer in women and the second leading cause of cancer death worldwide. Triple-negative breast cancer (TNBC) is a highly aggressive breast cancer subtype responsible for 10-20% of breast cancers. The limite

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8195e053aad6954ee905c773b08d2991
https://doi.org/10.1158/1557-3125.advbc17-a71

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Cytotoxicity and anti-tumor effects of new ruthenium complexes on triple negative breast cancer cells

Autor: Rodrigo S. Corrêa, Márcia Regina Cominetti, Angelica E. Graminha, Cecília Patrícia Popolin, Javier Ellena, Legna Colina-Vegas, João P. B. Reis, Amanda Blanque Becceneri, Marcio Aurélio Pinheiro Almeida, Alzir A. Batista

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
PLoS ONE
PLoS ONE, Vol 12, Iss 9, p e0183275 (2017)

Triple-negative breast cancer (TNBC) is a highly aggressive breast cancer subtype. The high rate of metastasis associated to the fact that these cells frequently display multidrug resistance, make the treatment of metastatic disease difficult. Develo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d03276501bded70d28b35a0a20ab5b37
https://doi.org/10.1371/journal.pone.0183275

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