Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Ce Dou"'
Autor:
Zihan Deng, Chuan Yang, Tingwen Xiang, Ce Dou, Dong Sun, Qijie Dai, Zhiguo Ling, Jianzhong Xu, Fei Luo, Yueqi Chen
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-23 (2024)
Abstract Osteoarthritis (OA) is a common degenerative joint disease that can cause severe pain, motor dysfunction, and even disability. A growing body of research indicates that gut microbiota and their associated metabolites are key players in maint
Externí odkaz:
https://doaj.org/article/3dfffe71d2a74879a9cb9b3d431c92b7
Publikováno v:
Genes and Diseases, Vol 10, Iss 3, Pp 864-876 (2023)
The skeletal system is a dynamically balanced system, which undergoes continuous bone resorption and formation to maintain bone matrix homeostasis. As an important ADP-ribosylase and NAD+-dependent deacylase, SIRT6 (SIR2-like protein 6) is widely exp
Externí odkaz:
https://doaj.org/article/59ab74a4ee0b4b1fa4dddd3299a4ae8e
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-9 (2023)
Abstract Osteoporosis is associated with excessive activity of osteoclasts. In bone turn over, most osteoclasts undergo apoptosis after bone resorption and produce a large number of apoptotic bodies (ABs). However, the biological function of osteocla
Externí odkaz:
https://doaj.org/article/66ae6d6db1364e87bbc6329e8be3077f
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-19 (2023)
Abstract Osteoporosis (OP) is a metabolic bone disease characterized by decreased bone mass and increased bone fragility. The imbalance of bone homeostasis modulated by osteoclasts and osteoblasts is the most crucial pathological change in osteoporos
Externí odkaz:
https://doaj.org/article/feaed559ba744991ba452b17d6c859d3
Publikováno v:
Pharmacological Research, Vol 196, Iss , Pp 106943- (2023)
Bile acids (BAs), synthesized in the liver and modified by the gut microbiota, have been widely appreciated not only as simple lipid emulsifiers, but also as complex metabolic regulators and momentous signaling molecules, which play prominent roles i
Externí odkaz:
https://doaj.org/article/1ab9b56c8beb464eabd8315c4c3e60b8
Autor:
Mingming Zhang, Yuan Lin, Ruijing Chen, Haikuan Yu, Yi Li, Ming Chen, Ce Dou, Pengbin Yin, Licheng Zhang, Peifu Tang
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-20 (2023)
Abstract Cell death is a mystery in various forms. Whichever type of cell death, this is always accompanied by active or passive molecules release. The recent years marked the renaissance of the study of these molecules showing they can signal to and
Externí odkaz:
https://doaj.org/article/2fb1093f73044a7692b2077c03e52342
Autor:
Yun Bai, Xiaoshan Gong, Rui Dong, Zhen Cao, Ce Dou, Chuan Liu, Jianmei Li, Fei Kang, Jingjin Dai, Chunrong Zhao, Zhansong Tian, Jiulin Tan, Qijie Dai, Shiwu Dong
Publikováno v:
Genes and Diseases, Vol 9, Iss 2, Pp 456-465 (2022)
Endochondral bone formation is an important route for bone repair. Although emerging evidence has revealed the functions of long non-coding RNAs (lncRNAs) in bone and cartilage development, the effect of lncRNAs in endochondral bone repair is still l
Externí odkaz:
https://doaj.org/article/54104d1e0dea44429ab1a80daadcdb80
Publikováno v:
Bone Research, Vol 10, Iss 1, Pp 1-11 (2022)
Abstract The molecular control of osteoclast formation is still not clearly elucidated. Here, we show that a process of cell recognition mediated by Siglec15-TLR2 binding is indispensable and occurs prior to cell fusion in RANKL-mediated osteoclastog
Externí odkaz:
https://doaj.org/article/4d84fa4df7b14229b5c95e3e66922f21
Autor:
Ce Dou, Jianmei Li, Jian He, Fei Luo, Tao Yu, Qijie Dai, Yueqi Chen, Jianzhong Xu, Xiaochao Yang, Shiwu Dong
Publikováno v:
Bioactive Materials, Vol 6, Iss 12, Pp 4697-4706 (2021)
Antiresorptive drugs are widely used for treatment of osteoporosis and cancer bone metastasis, which function mainly through an overall inhibition of osteoclast. However, not all osteoclasts are “bone eaters”; preosteoclasts (pOCs) play anabolic
Externí odkaz:
https://doaj.org/article/222b52341c7a48ec96d5d386bcd8e05f
Autor:
Gehua Zhen, Yang Dan, Ruomei Wang, Ce Dou, Qiaoyue Guo, Melissa Zarr, Linda N. Liu, Lieping Chen, Ruoxian Deng, Yusheng Li, Zengwu Shao, Xu Cao
Publikováno v:
Bone Research, Vol 9, Iss 1, Pp 1-11 (2021)
Abstract Osteoporosis (OP) is a common age-related disease characterized by a deterioration of bone mass and structure that predisposes patients to fragility fractures. Pharmaceutical therapies that promote anabolic bone formation in OP patients and
Externí odkaz:
https://doaj.org/article/a8554920a26d4080a2d68a5e92d3aeba