Zobrazeno 1 - 10
of 1 580
pro vyhledávání: '"Cdk6"'
Autor:
Erick Damián Castañeda-Reyes, Alejandro Gonzalez-Almazán, Alán Lubbert-Licón, Najwa Farhana Yahya, Elvira Gonzalez de Mejia
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Melanoma is the most aggressive type of skin cancer and can metastasize during primary tumor formation. This research aimed to determine the relationship between the prevention of melanoma development in a mouse model treated with liposomes
Externí odkaz:
https://doaj.org/article/fc5a2e18921342b387218b2b4ac55bd8
Publikováno v:
Biology Direct, Vol 19, Iss 1, Pp 1-12 (2024)
Abstract Objective Retinal vascular endothelial cell (RVECs) injury is a major cause of morbidity and mortality among the patients with diabetes. RVECs dysfunction is the predominant pathological manifestation of vascular complication in diabetic ret
Externí odkaz:
https://doaj.org/article/8672eea464cd4f11aea077afbe2f330c
Akademický článek
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Autor:
Yang Wen, Xue Sun, Lingge Zeng, Shumei Liang, Deyu Li, Xiangtian Chen, Fanrui Zeng, Chao Zhang, Qiongyao Wang, Qinsong Zhong, Ling Deng, Linlang Guo
Publikováno v:
Advanced Science, Vol 11, Iss 38, Pp n/a-n/a (2024)
Abstract Small cell lung cancer (SCLC) is characterized by rapid development of chemoresistance and poor outcomes. Cyclin‐dependent kinase 4/6 inhibitors (CDK4/6is) are widely used in breast cancer and other cancer types. However, the molecular mec
Externí odkaz:
https://doaj.org/article/98628396adf645e4bd067c93c6042796
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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Publikováno v:
Zhongliu Fangzhi Yanjiu, Vol 50, Iss 7, Pp 666-674 (2023)
Objective To investigate the effects of lncRNA SBF2-AS1 on the proliferation and invasion of hepatoma cells by regulating the miR-372-3p/CDK6 pathway. Methods Bel7402 and SK-hep1 cells were selected as research objects. The expression levels of SBF2-
Externí odkaz:
https://doaj.org/article/786590244a004fa8b633f41f85a4064a
Autor:
Eva Quandt, Núria Masip, Sara Hernández‐Ortega, Abril Sánchez‐Botet, Laura Gasa, Ainhoa Fernández‐Elorduy, Sara Plutta, Joan Marc Martínez‐Láinez, Samuel Bru, Pau M. Munoz‐Torres, Martin Floor, Jordi Villà‐Freixa, May C. Morris, August Vidal, Alberto Villanueva, Josep Clotet, Mariana P. C. Ribeiro
Publikováno v:
Molecular Oncology, Vol 17, Iss 7, Pp 1228-1245 (2023)
Cyclin‐dependent kinases (CDKs), together with their cyclin partners, are the master cell cycle regulators. Remarkably, the cyclin family was extended to include atypical cyclins, characterized by distinctive structural features, but their partner
Externí odkaz:
https://doaj.org/article/4d91340f06a24d8eb0bf9f70674462b3
Publikováno v:
Molecules, Vol 29, Iss 11, p 2681 (2024)
CDK6 plays a key role in the regulation of the cell cycle and is considered a crucial target for cancer therapy. In this work, conformational transitions of CDK6 were identified by using Gaussian accelerated molecular dynamics (GaMD), deep learning (
Externí odkaz:
https://doaj.org/article/c1071fc903af472f8f0bc45aa888556e
Autor:
Tian Xia, Xin‐Yuan Dai, Ming‐Yi Sang, Xu Zhang, Feng Xu, Jing Wu, Liang Shi, Ji‐Fu Wei, Qiang Ding
Publikováno v:
Advanced Science, Vol 11, Iss 1, Pp n/a-n/a (2024)
Abstract IGF2BP2 is a new identified N6‐methyladenosine (m6A) reader and associated with poor prognosis in many tumors. However, its role and related mechanism in breast cancer, especially in triple‐negative breast cancer (TNBC), remains unclear.
Externí odkaz:
https://doaj.org/article/ca9d0956bc5044de8be8d138a01c1d94
Publikováno v:
Journal of Asthma and Allergy, Vol Volume 16, Pp 433-445 (2023)
Yi Xiong,1,2,* Yani Luo,2,* Ting Yuwen,2,* Jiana Li,2 Rongchang Chen,3 Fei Shi1 1Emergency Department, Shenzhen People’s Hospital, Shenzhen, Guangdong Province, People’s Republic of China; 2Biomedical Research Institute, Shenzhen Peki
Externí odkaz:
https://doaj.org/article/759eab1abd06487d8f605f5673d6bf4a