Zobrazeno 1 - 10
of 7 497
pro vyhledávání: '"Cd4 t cell"'
Publikováno v:
Virology Journal, Vol 21, Iss 1, Pp 1-10 (2024)
Abstract Background Human adenoviruses (HAdVs) frequently cause common respiratory or gastrointestinal infections among children, adults, individuals with immune deficiencies, and other vulnerable populations with varying degree of symptoms, ranging
Externí odkaz:
https://doaj.org/article/336c3f3954434751972ddb3955a2cfb9
Autor:
Gholamreza Azizi, Bram Van den Broek, Larissa Lumi Watanabe Ishikawa, Hamed Naziri, Reza Yazdani, Guang-Xian Zhang, Bogoljub Ciric, Abdolmohamad Rostami
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-15 (2024)
Abstract Background The IL-7 receptor alpha (IL-7Rα) binds both IL-7 and thymic stromal lymphopoietin (TSLP). IL-7Rα is essential for the development and survival of naive CD4+ T cells and their differentiation to effector/memory CD4+ T cells. Mice
Externí odkaz:
https://doaj.org/article/846668fffe0b4fe28d72c1b46acd5f96
Autor:
Jing Xu, Jilong Ren, Kai Xu, Minghui Fang, Meina Ka, Fei Xu, Xin Wang, Jing Wang, Zhiqiang Han, Guihai Feng, Ying Zhang, Tang Hai, Wei Li, Zheng Hu
Publikováno v:
Animal Models and Experimental Medicine, Vol 7, Iss 4, Pp 584-590 (2024)
Abstract Background Pig organ xenotransplantation is a potential solution for the severe organ shortage in clinic, while immunogenic genes need to be eliminated to improve the immune compatibility between humans and pigs. Current knockout strategies
Externí odkaz:
https://doaj.org/article/b1dbc797368e421db1ed5493f81a5241
Autor:
Lifang Li, Danyang Li, Jingnan Jin, Fanfan Xu, Ni He, Yingjie Ren, Xiaokun Wang, Liting Tian, Biying Chen, Xiaoju Li, Zihong Chen, Lanxin Zhang, Lukuan Qiao, Lihua Wang, Jianjian Wang
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-17 (2024)
Abstract Background Myasthenia gravis (MG) is an autoimmune disease characterized by pathogenic antibodies that target structures of the neuromuscular junction. The evidence suggests that the regulation of long noncoding RNAs (lncRNAs) that is mediat
Externí odkaz:
https://doaj.org/article/1518a2690e65474c8442ea909590c188
Publikováno v:
Zhongguo quanke yixue, Vol 27, Iss 32, Pp 4009-4014 (2024)
Background HIV/AIDS is associated with depression, which increases the risk of HIV-associated neurocognitive disorders (HAND) and reduces patient compliance with antiretroviral therapy (ART), exacerbating the risk of HIV transmission. Few domestic st
Externí odkaz:
https://doaj.org/article/a4fb9193b1ec45fea7f94a1967e234c9
Autor:
Xiaomin Liu, Siyu Zhou, Mengjie Huang, Ming Zhao, Weiguang Zhang, Qun Liu, Kangkang Song, Xu Wang, Jiaona Liu, Qing OuYang, Zheyi Dong, Ming Yang, Zhenzhen Li, Li Lin, Yi Liu, Yang Yu, Simin Liao, Jian Zhu, Lin Liu, Wenge Li, Linpei Jia, Aihua Zhang, Chaomin Guo, LiuYang Yang, Qing gang Li, Xueyuan Bai, Ping Li, Guangyan Cai, Qianjin Lu, Xiangmei Chen
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-13 (2024)
Abstract Background Lupus nephritis (LN) is the most common cause of kidney injury in systemic lupus erythematosus (SLE) patients and is associated with increased mortality. DNA methylation, one of the most important epigenetic modifications, has bee
Externí odkaz:
https://doaj.org/article/426356896e9e45d7bfca3833edd95a3a
Publikováno v:
Skeletal Muscle, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Background This study aims to investigate the involvement of acid sphingomyelinase (ASM) in the pathology of dermatomyositis (DM), making it a potential therapeutic target for DM. Methods Patients with DM and healthy controls (HCs) were incl
Externí odkaz:
https://doaj.org/article/915bcd96fd3e429aa386df2cdde38710
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundBreast cancer (BC) remains a significant contributor to female mortality globally, with inflammation and the immune system implicated in its pathogenesis. To elucidate potential causal relationships, we evaluated the relationship among 731
Externí odkaz:
https://doaj.org/article/140f95fd0cca46e8b530316401417533
Autor:
Zhuoya Sun, Biao Gao, Lai Song, Biying Wang, Junfeng Li, Hao Jiang, Xuerui Li, Yang Yu, Zishan Zhou, Zizhong Yang, Xiaohui Sun, Tianyu Jiao, Xiao Zhao, Shichun Lu, Shunchang Jiao
Publikováno v:
Heliyon, Vol 10, Iss 18, Pp e37233- (2024)
Background: Microvascular invasion (MVI) is associated with an unfavorable prognosis and early recurrence of hepatocellular carcinoma (HCC), which is the crucial pathological hallmark of immunotherapy. While microvascular invasion (MVI) in hepatocell
Externí odkaz:
https://doaj.org/article/fe29fd74fd58439b8ade1976378c7a38
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionThyroid-associated ophthalmopathy (TAO) is considered to be an organ-specific autoimmune disease. Polymorphonuclear neutrophils (PMN) have been implicated in the pathogenesis of TAO. However, little is known about the role of PMN in the d
Externí odkaz:
https://doaj.org/article/6fde6d1285fe4189a8f03bd8aaaddaca