Zobrazeno 1 - 10
of 7 502
pro vyhledávání: '"Cd4 t cell"'
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-20 (2024)
Abstract Background Within the tumor microenvironment, altered lipid metabolism promotes cancer cell malignancy by activating oncogenic cascades; however, impact of lipid metabolism in CD4+ tumor-infiltrating lymphocytes (TILs) remains poorly underst
Externí odkaz:
https://doaj.org/article/5c470a24708949918e126c8e65b3fda8
Publikováno v:
Zhongguo quanke yixue, Vol 27, Iss 32, Pp 4009-4014 (2024)
Background HIV/AIDS is associated with depression, which increases the risk of HIV-associated neurocognitive disorders (HAND) and reduces patient compliance with antiretroviral therapy (ART), exacerbating the risk of HIV transmission. Few domestic st
Externí odkaz:
https://doaj.org/article/a4fb9193b1ec45fea7f94a1967e234c9
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-14 (2024)
Abstract Background Premature ovarian insufficiency (POI) is an immune-related condition. Dihydroberberine (dhBBR) plays a regulatory role in maintaining the T-helper 17 (Th17)/regulatory T (Treg) cell balance. This study aimed to explore the action
Externí odkaz:
https://doaj.org/article/edbdc906ebab4266bc397d630b1bb6d6
Publikováno v:
BMC Microbiology, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Gut microbes are important regulators of host health and can also function as disease indicators. Lactiplantibacilllus plantarum(L. plantarum)used as express and delivery vaccines for mucosal immunity have been shown to activate s
Externí odkaz:
https://doaj.org/article/ee2641affa7a426daae78e5f7d1190b0
Publikováno v:
Virology Journal, Vol 21, Iss 1, Pp 1-10 (2024)
Abstract Background Human adenoviruses (HAdVs) frequently cause common respiratory or gastrointestinal infections among children, adults, individuals with immune deficiencies, and other vulnerable populations with varying degree of symptoms, ranging
Externí odkaz:
https://doaj.org/article/336c3f3954434751972ddb3955a2cfb9
Autor:
Gholamreza Azizi, Bram Van den Broek, Larissa Lumi Watanabe Ishikawa, Hamed Naziri, Reza Yazdani, Guang-Xian Zhang, Bogoljub Ciric, Abdolmohamad Rostami
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-15 (2024)
Abstract Background The IL-7 receptor alpha (IL-7Rα) binds both IL-7 and thymic stromal lymphopoietin (TSLP). IL-7Rα is essential for the development and survival of naive CD4+ T cells and their differentiation to effector/memory CD4+ T cells. Mice
Externí odkaz:
https://doaj.org/article/846668fffe0b4fe28d72c1b46acd5f96
Autor:
Jing Xu, Jilong Ren, Kai Xu, Minghui Fang, Meina Ka, Fei Xu, Xin Wang, Jing Wang, Zhiqiang Han, Guihai Feng, Ying Zhang, Tang Hai, Wei Li, Zheng Hu
Publikováno v:
Animal Models and Experimental Medicine, Vol 7, Iss 4, Pp 584-590 (2024)
Abstract Background Pig organ xenotransplantation is a potential solution for the severe organ shortage in clinic, while immunogenic genes need to be eliminated to improve the immune compatibility between humans and pigs. Current knockout strategies
Externí odkaz:
https://doaj.org/article/b1dbc797368e421db1ed5493f81a5241
Autor:
Lifang Li, Danyang Li, Jingnan Jin, Fanfan Xu, Ni He, Yingjie Ren, Xiaokun Wang, Liting Tian, Biying Chen, Xiaoju Li, Zihong Chen, Lanxin Zhang, Lukuan Qiao, Lihua Wang, Jianjian Wang
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-17 (2024)
Abstract Background Myasthenia gravis (MG) is an autoimmune disease characterized by pathogenic antibodies that target structures of the neuromuscular junction. The evidence suggests that the regulation of long noncoding RNAs (lncRNAs) that is mediat
Externí odkaz:
https://doaj.org/article/1518a2690e65474c8442ea909590c188
Autor:
Xiaomin Liu, Siyu Zhou, Mengjie Huang, Ming Zhao, Weiguang Zhang, Qun Liu, Kangkang Song, Xu Wang, Jiaona Liu, Qing OuYang, Zheyi Dong, Ming Yang, Zhenzhen Li, Li Lin, Yi Liu, Yang Yu, Simin Liao, Jian Zhu, Lin Liu, Wenge Li, Linpei Jia, Aihua Zhang, Chaomin Guo, LiuYang Yang, Qing gang Li, Xueyuan Bai, Ping Li, Guangyan Cai, Qianjin Lu, Xiangmei Chen
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-13 (2024)
Abstract Background Lupus nephritis (LN) is the most common cause of kidney injury in systemic lupus erythematosus (SLE) patients and is associated with increased mortality. DNA methylation, one of the most important epigenetic modifications, has bee
Externí odkaz:
https://doaj.org/article/426356896e9e45d7bfca3833edd95a3a
Publikováno v:
Skeletal Muscle, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Background This study aims to investigate the involvement of acid sphingomyelinase (ASM) in the pathology of dermatomyositis (DM), making it a potential therapeutic target for DM. Methods Patients with DM and healthy controls (HCs) were incl
Externí odkaz:
https://doaj.org/article/915bcd96fd3e429aa386df2cdde38710