Zobrazeno 1 - 10
of 358
pro vyhledávání: '"Ccrf cem"'
Autor:
Gabriel O. Rodríguez-Vázquez, Adriana O. Diaz-Quiñones, Nataliya Chorna, Iris K. Salgado-Villanueva, Jing Tang, Walter I. Silva Ortiz, Héctor M. Maldonado
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 166, Iss , Pp 115352- (2023)
Drug synergy allows reduced dosing, side effects and tolerance. Optimization of drug synergy chemotherapy is fundamental in acute lymphocytic leukemia and other cancers. This study aimed to analyze the pharmacodynamic synergy between the anti-metabol
Externí odkaz:
https://doaj.org/article/be8c1f94e8c7415fa3972439a447c45f
Autor:
Patrycja Wińska, Łukasz Widło, Elżbieta Senkara, Mirosława Koronkiewicz, Jarosław M. Cieśla, Alicja Krzyśko, Katarzyna Skierka, Joanna Cieśla
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Thymidylate synthase (TS), dihydrofolate reductase (DHFR), and serine hydroxymethyltransferase (SHMT) constitute the thymidylate synthesis cycle providing thymidylate for DNA synthesis and repair. Our previous studies indicated that TS and DHFR are t
Externí odkaz:
https://doaj.org/article/7996ee4219e6416abfab7151045eb4d9
Akademický článek
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Autor:
Jie Tan, Zongqiang Lai, Liping Zhong, Zhenghua Zhang, Rong Zheng, Jing Su, Yong Huang, Panpan Huang, Hui Song, Nuo Yang, Sufang Zhou, Yongxiang Zhao
Publikováno v:
Nanoscale Research Letters, Vol 13, Iss 1, Pp 1-8 (2018)
Abstract A convenient, low-cost, and highly sensitive fluorescent aptasensor for detection of leukemia has been developed based on graphene oxide-aptamer complex (GO-apt). Graphene oxide (GO) can absorb carboxyfluorescein-labeled Sgc8 aptamer (FAM-ap
Externí odkaz:
https://doaj.org/article/4df30dc313bb412e9de2e6a9c76503b8
Autor:
A. Grebinyk, S. Prylutska, I. Grynyuk, B. Kolp, V. Hurmach, T. Sliva, V. Amirkhanov, V. Trush, O. Matyshevska, M. Slobodyanik, Yu. Prylutskyy, M. Frohme, U. Ritter
Publikováno v:
Nanoscale Research Letters, Vol 13, Iss 1, Pp 1-9 (2018)
Abstract New representative of carbacylamidophosphates - diphenyl-N-(trichloroacetyl)-amidophosphate (HL), which contains two phenoxy substituents near the phosphoryl group, was synthesized, identified by elemental analysis and IR and NMR spectroscop
Externí odkaz:
https://doaj.org/article/998639c7606d4713a6dea07b04974eb2
Publikováno v:
Cells, Vol 10, Iss 12, p 3584 (2021)
Biological systems are dynamic systems featuring two very common characteristics; Initial conditions and progression over time. Conceptualizing this on tumour models it can lead to important conclusions about disease progression, as well as the disea
Externí odkaz:
https://doaj.org/article/d2ec6a88ba5743238626630b775fda8a
Autor:
Shadab SHAHRIARI, Maryam BAKHSHI, Ahmad Reza SHAHVERDI, Azar BERAHMEH, Farnaz SAFAVIFAR, Mohammad Reza KHORRAMIZADEH
Publikováno v:
Iranian Journal of Public Health, Vol 46, Iss 3 (2017)
Background: High temperatures have destructive effects on cancer cells by damaging proteins and structures within cells. Gold nanoparticles (AuNPs) can act as drug delivery vehicles, especially for cancer therapy. Due to the selective intake of aspar
Externí odkaz:
https://doaj.org/article/acb5ec31a5264381a785cce283e0f8fa
Publikováno v:
Makara Journal of Health Research, Vol 18, Iss 1, Pp 7-12 (2014)
Mahkota Dewa as a traditional plant has been commonly used as traditional cancer medication. However, the mechanism of usage is not yet clear. The objective of this study is to know the mechanism of the protection effect of Mahkota Dewa on Benzo(a)py
Externí odkaz:
https://doaj.org/article/96b7a1914c8f404eb71754b46ec98b24
Autor:
Marketa Bernaskova, Nadine Kretschmer, Wolfgang Schuehly, Antje Huefner, Robert Weis, Rudolf Bauer
Publikováno v:
Molecules, Vol 19, Iss 1, Pp 1223-1237 (2014)
Biphenyl neolignans such as honokiol and magnolol, which are the major active constituents of the Asian medicinal plant Magnolia officinalis, are known to exert a multitude of pharmacological and biological activities. Among these, cytotoxic and tumo
Externí odkaz:
https://doaj.org/article/c156c74c67104879af6253ab0d358e2b
Publikováno v:
Toxins, Vol 11, Iss 7, p 399 (2019)
Staphylococcal food poisoning is a result of ingestion of Staphylococcal enterotoxins (SEs) produced by Staphylococcus aureus. Staphylococcal enterotoxin type A (SEA) is the predominant toxin produced by S. aureus strains isolated from food-poisoning
Externí odkaz:
https://doaj.org/article/c37d893fd44c493aaf94162e7dec8208