Zobrazeno 1 - 10
of 179
pro vyhledávání: '"Cb2 agonist"'
Anti-inflammatory and antinociceptive effects of the selective cannabinoid CB2 receptor agonist ABK5
Publikováno v:
Journal of Pharmacological Sciences, Vol 145, Iss 4, Pp 319-326 (2021)
Cannabinoid receptors are a potential target for anti-inflammatory and pain therapeutics. There are two subtypes, CB1 and CB2, and Δ9-tetrahydrocannabinol activates both of them, providing an analgesic effect but also psychoactive side effects. The
Externí odkaz:
https://doaj.org/article/ac06208db58d40e38807b7cf24277a36
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
Previous work from our laboratory showed that a CB2 selective agonist, O-1966, blocked the proliferative response of C57BL/6 mouse spleen cells exposed to spleen cells of C3HeB/FeJ mice in vitro in the mixed lymphocyte reaction (MLR). The MLR is wide
Externí odkaz:
https://doaj.org/article/ea44f8c02cfd4d0b9892db7071acca4a
Autor:
Gamal A. Mohamed, Abdelsattar M. Omar, Dana F. AlKharboush, Mona A. Fallatah, Ikhlas A. Sindi, Dina S. El-Agamy, Sabrin R. M. Ibrahim
Publikováno v:
Molecules, Vol 28, Iss 4, p 1761 (2023)
The discovery of natural drug metabolites is a leading contributor to fulfilling the sustainable development goal of finding solutions to global health challenges. Depsidones are a class of polyketides that have been separated from lichens, fungi, sp
Externí odkaz:
https://doaj.org/article/50ce7db4b2604968847de06ba6dd7637
Autor:
Xiaojie Liu, Hao Yu, Bixuan Chen, Vladislav Friedman, Lianwei Mu, Thomas J. Kelly, Gonzalo Ruiz-Pérez, Li Zhao, Xiaowen Bai, Cecilia J. Hillard, Qing-song Liu
Publikováno v:
Biomedicines, Vol 10, Iss 8, p 1776 (2022)
In addition to motor dysfunction, patients with Parkinson’s disease (PD) are often affected by neuropsychiatric disorders, such as anxiety and depression. In animal models, activation of the endocannabinoid (eCB) system produces anxiolytic and anti
Externí odkaz:
https://doaj.org/article/7f6ee6c6f9634bcb95861debdc085010
Akademický článek
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Publikováno v:
Frontiers in Pediatrics, Vol 8 (2020)
Introduction: Neonatal HIE is associated with high morbidity and mortality. Current research, is focused on developing alternative treatments to therapeutic hypothermia for treatment of HIE. The endocannabinoid system is known to be influential in ne
Externí odkaz:
https://doaj.org/article/f7d1d836bd054e89983ca5ffa158ffc9
Akademický článek
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Akademický článek
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Autor:
Jiaxiang Bai, Gaoran Ge, Yijun Wang, Wenhao Zhang, Qing Wang, Wei Wang, Xiaobin Guo, Binqing Yu, Yaozeng Xu, Huilin Yang, Xuesong Zhu, Mingjun Wang, Dechun Geng
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 116, Iss , Pp 109025- (2019)
Rheumatoid arthritis (RA) is a chronic, inflammatory, synovitis-dominated systemic disease with unknown etiology. RA is characterized by the involvement of multiple affected joints, symmetry, and invasive arthritis of the limbs, which can lead to joi
Externí odkaz:
https://doaj.org/article/a4cc736ad79d4b3fb5dfac798d39a0a5
Publikováno v:
Molecules, Vol 26, Iss 8, p 2126 (2021)
Cannabinoids comprise different classes of compounds, which aroused interest in recent years because of their several pharmacological properties. Such properties include analgesic activity, bodyweight reduction, the antiemetic effect, the reduction o
Externí odkaz:
https://doaj.org/article/46a2eddb611e4bfdbd016bb44337736d