Extended sample size calculations for evaluation of prediction models using a threshold for classification

Autor: Whittle, Rebecca, Ensor, Joie, Archer, Lucinda, Collins, Gary S., Dhiman, Paula, Denniston, Alastair, Alderman, Joseph, Legha, Amardeep, van Smeden, Maarten, Moons, Karel G., Cazier, Jean-Baptiste, Riley, Richard D., Snell, Kym I. E.

When evaluating the performance of a model for individualised risk prediction, the sample size needs to be large enough to precisely estimate the performance measures of interest. Current sample size guidance is based on precisely estimating calibrat

Externí odkaz: http://arxiv.org/abs/2406.19673

Identification and validation of a machine learning model of complete response to radiation in rectal cancer reveals immune infiltrate and TGFβ as key predictors

Autor: Blake, Andrew, Buffa, Francesca, Domingo, Enric, Higgins, Geoffrey, Holmes, Christopher, Koelzer, Viktor, Leedham, Simon, Maughan, Timothy, McKenna, Gillies, Robineau, James, Tomlinson, Ian, Youdell, Michael, Quirke, Philip, Richman, Susan, Sebag-Montefiore, David, Seymour, Matthew, West, Nicholas, Dunne, Philip, Kennedy, Richard, Lawler, Mark, Redmond, Keara, Salto-Tellez, Manuel, Campbell, Peter, Chatzipli, Aikaterini, Hardy, Claire, McDermott, Ultan, Bach, Simon, Beggs, Andrew, Cazier, Jean-Baptiste, Middleton, Gary, Morton, Dion, Whalley, Celina, Brown, Louise, Kaplan, Richard, Murray, Graeme, Wilson, Richard, Adams, Richard, Sullivan, Richard, Samuel, Leslie, Harkin, Paul, Walker, Steven, Hill, Jim, Wu, Chieh-Hsi, Horgan, Dennis, Rathee, Sanjay, Gollins, Simon, Begum, Rubina, Quirke, Phil, Barberis, Alessandro, Hassanieh, Sylvana, Mahmood, Umair, Buffa, Francesca M., Maughan, Timothy S.

Publikováno v: In eBioMedicine August 2024 106

COVID-19 prevalence and mortality in patients with cancer and the effect of primary tumour subtype and patient demographics: a prospective cohort study

Autor: Gault, Abigail, Agnieszka, Michael, Bedair, Ahmed, Ghaus, Aisha, Akingboye, Akinfemi, Maynard, Alec, Pawsey, Alexander, Suwaidan, Ali Abdulnabi, Okines, Alicia, Massey, Alison, Kwan, Amy, Ferreira, Ana, Angelakas, Angelos, Wu, Anjui, Tivey, Ann, Armstrong, Anne, Madhan, Annet, Pillai, Annet, Poon-King, Ashley, Kurec, Bartlomiej, Usborne, Caroline, Dobeson, Caroline, Thirlwell, Christina, Mitchell, Christian, Sng, Christopher, Scrase, Christopher, Jingree, Christopher, Brunner, Clair, Fuller, Claire, Griffin, Clare, Barrington, Craig, Muller, Daniel, Ottaviani, Diego, Gilbert, Duncan, Tacconi, Eliana, Copson, Ellen, Renninson, Emily, Cattell, Emma, Burke, Emma, Smith, Fiona, Holt, Francesca, Soosaipillai, Gehan, Boyce, Hayley, Shaw, Heather, Hollis, Helen, Bowyer, Helen, Anil, Iris, Illingworth, Jack, Gibson, Jack, Bhosle, Jaishree, Best, James, Barrett, Jane, Noble, Jillian, Sacco, Joseph, Chacko, Joseph, Chackathayil, Julia, Banfill, Kathryn, Feeney, Laura, Horsley, Laura, Cammaert, Lauren, Mukherjee, Leena, Eastlake, Leonie, Devereaux, Louise, Melcher, Lucinda, Cook, Lucy, Teng, Mabel, Hewish, Madeleine, Bhattacharyya, Madhumita, Choudhury, Mahbuba, Baxter, Mark, Scott-Brown, Martin, Fittall, Matthew, Tilby, Michael, Rowe, Michael, Alihilali, Mohammed, Galazi, Myria, Yousaf, Nadia, Chopra, Neha, Cox, Nicola, Chan, Olivia, Sheikh, Omar, Ramage, Paul, Greaves, Paul, Leonard, Pauline, Hall, Peter S, Naksukpaiboon, Piangfan, Corrie, Pippa, Peck, Rahul, Sharkey, Rachel, Bolton, Rachel, Sargent, Rebecca, Jyothirmayi, Rema, Goldstein, Robert, Oakes, Roderick, Shotton, Rohan, Kanani, Ruhi, Board, Ruth, Pettengell, Ruth, Claydon, Ryan, Moody, Sam, Massalha, Samah, Kathirgamakarthigeyan, Sangary, Dolly, Saoirse, Derby, Sarah, Lowndes, Sarah, Benafif, Sarah, Eeckelaers, Sarah, Kingdon, Sarah, Ayers, Sarah, Brown, Sean, Ellis, Shawn, Parikh, Shefali, Pugh, Sian, Shamas, Simon, Wyatt, Simon, Grumett, Simon, Lau, Sin, Wong, Yien Ning Sophia, McGrath, Sophie, Cornthwaite, Stephanie, Hibbs, Stephen, Tillet, Tania, Rabbi, Taslima, Robinson, Tim, Roques, Tom, Angelis, Vasileios, Woodcock, Victoria, Brown, Victoria, Peng, YingYing, Drew, Yvette, Hudson, Zoe, Lee, Lennard Y W ^*, Cazier, Jean-Baptiste ^*, Starkey, Thomas ^*, Briggs, Sarah E W, Arnold, Roland, Bisht, Vartika, Booth, Stephen, Campton, Naomi A, Cheng, Vinton W T, Collins, Graham, Curley, Helen M, Earwaker, Philip, Fittall, Matthew W, Gennatas, Spyridon, Goel, Anshita, Hartley, Simon, Hughes, Daniel J, Kerr, David, Lee, Alvin J X, Lee, Rebecca J, Lee, Siow Ming, Mckenzie, Hayley, Middleton, Chris P, Murugaesu, Nirupa, Newsom-Davis, Tom, Olsson-Brown, Anna C, Palles, Claire, Powles, Thomas, Protheroe, Emily A, Purshouse, Karin, Sharma-Oates, Archana, Sivakumar, Shivan, Smith, Ashley J, Topping, Oliver, Turnbull, Chris D, Várnai, Csilla, Briggs, Adam D M, Middleton, Gary ^*, Kerr, Rachel

Publikováno v: In The Lancet Oncology October 2020 21(10):1309-1316

Integrative analysis of spontaneous CLL regression highlights genetic and microenvironmental interdependency in CLL

Autor: Kwok, Marwan ^{1, 1, 2, 3, *}, Oldreive, Ceri ^{1, *}, Rawstron, Andy C. ³, Goel, Anshita ^{1, 4}, Papatzikas, Grigorios ^{1, 4}, Jones, Rhiannon E. ⁵, Drennan, Samantha ⁶, Agathanggelou, Angelo ¹, Sharma-Oates, Archana ^{1, 4}, Evans, Paul ³, Smith, Edward ¹, Dalal, Surita ³, Mao, Jingwen ¹, Hollows, Robert ¹, Gordon, Naheema ¹, Hamada, Mayumi ¹, Davies, Nicholas J. ¹, Parry, Helen ^{2, 7}, Beggs, Andrew D. ¹, Munir, Talha ³, Moreton, Paul ⁸, Paneesha, Shankara ⁹, Pratt, Guy ^{1, 2}, Taylor, A. Malcolm R. ¹, Forconi, Francesco ⁶, Baird, Duncan M. ⁵, Cazier, Jean-Baptiste ^{1, 4}, Moss, Paul ^{2, 7}, Hillmen, Peter ^{3, 10}, Stankovic, Tatjana ^{2, 1, †}

Publikováno v: In Blood 6 February 2020 135(6):411-428

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