Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Caymen Novak"'
Publikováno v:
APL Bioengineering, Vol 2, Iss 3, Pp 031701-031701-17 (2018)
Ovarian cancer remains a deadly diagnosis with an 85% recurrence rate and a 5-year survival rate of only 46%. The poor outlook of this disease has improved little over the past 50 years owing to the lack of early detection, chemoresistance and the
Externí odkaz:
https://doaj.org/article/03c1c23c3bdc4c44b5f1c9a683ef289b
Autor:
Faisal Fakhouri, Matthew Joseph, Megan Ballinger, Vasudha Shukla, David Weimar, Caymen Novak, Samir Ghadiali, Arunark Kolipaka
Publikováno v:
Investigative Radiology. 58:299-306
Autor:
Katelyn Dunigan-Russell, Michael J. Yaeger, Myles X. Hodge, Brita Kilburg-Basnyat, Sky W. Reece, Anastasiya Birukova, Marissa A. Guttenberg, Caymen Novak, Sangwoon Chung, Brandie Michelle Ehrmann, E. Diane Wallace, Debra Tokarz, Nairrita Majumder, Li Xia, John W. Christman, Jonathan Shannahan, Megan N. Ballinger, Salik Hussain, Saame Raza Shaikh, Robert M. Tighe, Kymberly M. Gowdy
Publikováno v:
Toxicology and Applied Pharmacology. 462:116381
Publikováno v:
J Biomech Eng
Cells within the lung micro-environment are continuously subjected to dynamic mechanical stimuli which are converted into biochemical signaling events in a process known as mechanotransduction. In pulmonary diseases, the abrogated mechanical conditio
Publikováno v:
Biotechnol Bioeng
Breast cancer cells experience a range of shear stresses in the tumor microenvironment (TME). However most current in vitro three-dimensional (3D) models fail to systematically probe the effects of this biophysical stimuli on cancer cell metastasis,
Publikováno v:
Am J Respir Crit Care Med
American Journal of Respiratory and Critical Care Medicine
American Journal of Respiratory and Critical Care Medicine
Rationale: Macrophages are the most abundant immune cell in the alveoli and small airways and are traditionally viewed as a homogeneous population during health. Whether distinct subsets of airspace macrophages are present in healthy humans is unknow
Autor:
Eric N. Horst, Caymen Novak, Geeta Mehta, Pooja Mehta, Michael E. Bregenzer, Taylor Repetto, Catherine S. Snyder
Publikováno v:
Annals of translational medicine. 7(Suppl 8)
Ovarian cancer (OC) is a heterogeneous disease usually diagnosed at a late stage. Experimental in vitro models that faithfully capture the hallmarks and tumor heterogeneity of OC are limited and hard to establish. We present a protocol that enables e
Autor:
Ciara Davis, Caymen Novak, Michael E. Bregenzer, Eric N. Horst, Pooja Mehta, Catherine S. Snyder, Shreya Raghavan, Geeta Mehta
Publikováno v:
J Vis Exp
In this protocol, we outline the procedure for generation of tumor spheroids within 384-well hanging droplets to allow for high-throughput screening of anti-cancer therapeutics in a physiologically representative microenvironment. We outline the form
Autor:
Caymen Novak, Michael E. Bregenzer, Catherine S. Snyder, Pooja Mehta, Shreya Raghavan, Geeta Mehta, Eric N. Horst
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216564 (2019)
PLoS ONE
PLoS ONE
Tumors are not merely cancerous cells that undergo mindless proliferation. Rather, they are highly organized and interconnected organ systems. Tumor cells reside in complex microenvironments in which they are subjected to a variety of physical and ch
Autor:
Laila Guessous, Caymen Novak
Publikováno v:
2017 ASEE Annual Conference & Exposition Proceedings.