Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Cayman Stephen"'
Publikováno v:
ADMET and DMPK, Vol 6, Iss 3, Pp 200-214 (2018)
Secondary plant metabolites are evolutionary-designed molecules that interact with multiple biological targets in human organisms. Identification of pharmacologically active phytochemicals is usually a time consuming and costly process. Cellular memb
Externí odkaz:
https://doaj.org/article/041b27926d5042909287edfe4383f822
Autor:
Angelo J. Antone, Yuping Bao, Cayman Stephen, Lukasz Ciesla, Nicholas Beyer, Jennifer Sherwood, Josiah Sowell, Jessica Irvin
Publikováno v:
Nanoscale. 11:6352-6359
The lack of suitable tools for the identification of potential drug leads from complex matrices is a bottleneck in drug discovery. Here, we report a novel method to screen complex matrices for new drug leads targeting transmembrane receptors. Using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3145ce016510af5c4b9daf2bd259f46
https://doi.org/10.1039/c9nr01292c
https://doi.org/10.1039/c9nr01292c
Publikováno v:
J Pharm Biomed Anal
The use of natural products has been shown to be a fruitful approach in the discovery of novel pharmaceuticals. In fact, many currently approved drugs originated from compounds that were first identified in nature. Chemical diversity of natural compo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bbb39485f3a40f1b9a936c519b0a430
https://doi.org/10.1016/j.jpba.2021.114553
https://doi.org/10.1016/j.jpba.2021.114553
Autor:
Samuel E. Scopel, Edward F Griffin, Cayman Stephen, Kim A. Caldwell, Adam C. Holzhauer, Laura A. Berkowitz, Ryan A. Tuckey, Madeline A Vaji, Guy A. Caldwell
Publikováno v:
Disease Models & Mechanisms, Vol 12, Iss 2 (2019)
Disease Models & Mechanisms
Disease Models & Mechanisms
Allele-specific distinctions in the human apolipoprotein E (APOE) locus represent the best-characterized genetic predictor of Alzheimer's disease (AD) risk. Expression of isoform APOEε2 is associated with reduced risk, while APOEε3 is neutral and A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e76f41691bd22dad292c7e1997bf335a
http://dmm.biologists.org/content/12/2/dmm037218
http://dmm.biologists.org/content/12/2/dmm037218
Publikováno v:
ADMET and DMPK
Volume 6
Issue 3
ADMET and DMPK, Vol 6, Iss 3, Pp 200-214 (2018)
Volume 6
Issue 3
ADMET and DMPK, Vol 6, Iss 3, Pp 200-214 (2018)
Secondary plant metabolites are evolutionary-designed molecules that interact with multiple biological targets in human organisms. Identification of pharmacologically active phytochemicals is usually a time consuming and costly process. Cellular memb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::073518b519cd52d78c194e689b35b0c6
https://hrcak.srce.hr/file/302774
https://hrcak.srce.hr/file/302774
Publikováno v:
Nanoscale; 4/7/2019, Vol. 11 Issue 13, p5777-5797, 21p
Autor:
Sherwood, Jennifer, Sowell, Josiah, Beyer, Nicholas, Irvin, Jessica, Stephen, Cayman, Antone, Angelo J., Bao, Yuping, Ciesla, Lukasz M.
Publikováno v:
Nanoscale; 4/7/2019, Vol. 11 Issue 13, p6352-6359, 8p
Publikováno v:
Derivatives Week. 5/26/2002, Vol. 11 Issue 21, p10-10. 1p.