Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Cayla M. Duffy"'
Publikováno v:
Nanomaterials, Vol 8, Iss 3, p 155 (2018)
The brain is the central regulator for integration and control of responses to environmental cues. Previous studies suggest that air pollution may directly impact brain health by triggering the onset of chronic neuroinflammation. We hypothesize that
Externí odkaz:
https://doaj.org/article/8c74c7a8ac16424488062a25a2e525c3
Autor:
Simon W. So, Kendra M. Fleming, Cayla M. Duffy, Joshua P. Nixon, David A. Bernlohr, Tammy A. Butterick
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 8; Pages: 4354
The microglial fatty-acid-binding protein 4-uncoupling protein 2 (FABP4-UCP2) axis is a key regulator of neuroinflammation in high-fat-diet (HFD)-fed animals, indicating a role for FABP4 in brain immune response. We hypothesized that the FABP4-UCP2 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c41169792dfc8498ea9d3c5a2129140d
https://pubmed.ncbi.nlm.nih.gov/35457171
https://pubmed.ncbi.nlm.nih.gov/35457171
Autor:
Tammy A. Butterick, Charles J. Billington, Joshua P. Nixon, Vijayakumar Mavanji, Catherine M. Kotz, Cayla M. Duffy
Publikováno v:
Neurobiology of Learning and Memory. 146:21-30
Orexin A is produced in neurons of the lateral, perifornical and dorsomedial regions of the lateral hypothalamic area, which then project widely throughout the central nervous system to regulate arousal state, sleep-wake architecture, energy homeosta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2dd9e8d59f0c4b566b3a0cce8771a61
https://doi.org/10.1016/j.nlm.2017.10.014
https://doi.org/10.1016/j.nlm.2017.10.014
Publikováno v:
Molecular and Cellular Neuroscience. 75:93-100
Palmitic acid (PA), an abundant dietary saturated fatty acid, contributes to obesity and hypothalamic dysregulation in part through increase in oxidative stress, insulin resistance, and neuroinflammation. Increased production of reactive oxygen speci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c264e0a42eab5e547768ee0b06d2449d
https://doi.org/10.1016/j.mcn.2016.07.003
https://doi.org/10.1016/j.mcn.2016.07.003
Publikováno v:
Neurobiology of learning and memory. 157
Midlife obesity is a risk factor for cognitive decline and is associated with the earlier onset of Alzheimer's disease (AD). Diets high in saturated fat potentiate the onset of obesity, microglial activation, and neuroinflammation. Signaling deficien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dba2ab04aec47a63c37fe433a0a7ec9a
https://pubmed.ncbi.nlm.nih.gov/30471346
https://pubmed.ncbi.nlm.nih.gov/30471346
Publikováno v:
Nanomaterials, Vol 8, Iss 3, p 155 (2018)
Nanomaterials; Volume 8; Issue 3; Pages: 155
Nanomaterials
Nanomaterials; Volume 8; Issue 3; Pages: 155
Nanomaterials
The brain is the central regulator for integration and control of responses to environmental cues. Previous studies suggest that air pollution may directly impact brain health by triggering the onset of chronic neuroinflammation. We hypothesize that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab225353d686c9a9a46ec2644a47a340
http://www.mdpi.com/2079-4991/8/3/155
http://www.mdpi.com/2079-4991/8/3/155
Autor:
Charles J. Billington, Catherine M. Kotz, Tammy A. Butterick, Lauren E. Wisdorf, Cayla M. Duffy, Joshua P. Nixon, Ce Yuan
Publikováno v:
Neuroscience Letters. 606:140-144
Excess dietary saturated fatty acids such as palmitic acid (PA) induce peripheral and hypothalamic inflammation. Hypothalamic inflammation, mediated in part by microglial activation, contributes to metabolic dysregulation. In rodents, high fat diet-i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e619af6437ccd15467b710473492314
https://doi.org/10.1016/j.neulet.2015.08.033
https://doi.org/10.1016/j.neulet.2015.08.033
Autor:
Tammy A. Butterick, Eric K. Long, Laura Hocum Stone, Edward O. McFalls, Rosemary F. Kelly, Christopher T. Holley, Megan E. Lindsey, Cayla M. Duffy
Publikováno v:
Journal of Surgical Research. 195:29-36
Hibernating myocardium is characterized by viable yet dysfunctional myocardium secondary to chronic ischemia, with studies demonstrating incomplete early recovery after coronary artery bypass graft (CABG). We tested whether mitochondrial fusion prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::359464ce0da622893bae478282702b61
https://doi.org/10.1016/j.jss.2014.12.052
https://doi.org/10.1016/j.jss.2014.12.052
Autor:
Megan E. Lindsey, Cayla M. Duffy, Herbert B. Ward, Christopher T. Holley, Jesus A Cabrera, Eric K. Long, Rosemary F. Kelly, Edward O. McFalls, Tammy A. Butterick
Publikováno v:
Journal of Surgical Research. 193:15-21
We have previously shown that mitochondrial uncoupling protein-2 (UCP-2) is increased in a swine model of hibernating myocardium (HM). Although UCP-2 reduces oxidant stress, it can promote inefficiency of the electron transport chain. In this study,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fec1983534fda7fdbbd40e2ac98645ee
https://doi.org/10.1016/j.jss.2014.08.003
https://doi.org/10.1016/j.jss.2014.08.003
Autor:
Shihab Ahmed, Joshua P. Nixon, Tammy A. Butterick, Vijayakumar Mavanji, Cayla M. Duffy, Ce Yuan
Publikováno v:
Journal of Visualized Experiments.
Nanoparticles found in air pollutants can alter neurotransmitter profiles, increase neuroinflammation, and alter brain function. Therefore, the assay described here will aid in elucidating the role of microglia in neuroinflammation and neurodegenerat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bb0b50c1dbbac111ccae606d7c931ec
https://doi.org/10.3791/54662-v
https://doi.org/10.3791/54662-v