Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Cayetano, Gonzalez"'
Autor:
Serena Mahnoor, Cristina Molnar, Diego Velázquez, Jose Reina, Salud Llamazares, Jan Peter Heinen, Jaume Mora, Cayetano Gonzalez
Publikováno v:
Open Biology, Vol 14, Iss 7 (2024)
Ewing sarcoma (EwS) is a cancer that arises in the bones and soft tissues, typically driven by the Ewing’s sarcoma breakpoint region 1-Friend leukemia virus integration 1 (EWS-FLI) oncogene. Implementation of genetically modified animal models of E
Externí odkaz:
https://doaj.org/article/3ae7d867978744aeb932d4c4bcc63c7a
Autor:
Qiannan Deng, Cheng Wang, Chwee Tat Koe, Jan Peter Heinen, Ye Sing Tan, Song Li, Cayetano Gonzalez, Wing-Kin Sung, Hongyan Wang
Publikováno v:
PLoS Biology, Vol 20, Iss 10 (2022)
Neural stem cells (NSCs) divide asymmetrically to balance their self-renewal and differentiation, an imbalance in which can lead to NSC overgrowth and tumor formation. The functions of Parafibromin, a conserved tumor suppressor, in the nervous system
Externí odkaz:
https://doaj.org/article/bf49b0e4c14d4019b05b0a6fbf4db8d0
Autor:
Regina Freier, Eric Aragón, Błażej Bagiński, Radoslaw Pluta, Pau Martin-Malpartida, Lidia Ruiz, Miriam Condeminas, Cayetano Gonzalez, Maria J. Macias
Publikováno v:
IUCrJ, Vol 8, Iss 2, Pp 281-294 (2021)
Thioredoxins (Trxs) are ubiquitous enzymes that regulate the redox state in cells. In Drosophila, there are two germline-specific Trxs, Deadhead (Dhd) and thioredoxin T (TrxT), that belong to the lethal(3)malignant brain tumor signature genes and to
Externí odkaz:
https://doaj.org/article/af238065ce634e0696fc25d54648569c
Autor:
Paula Climent-Cantó, Cristina Molnar, Paula Santabárbara-Ruiz, Cristina Prieto, Josep F. Abril, Florenci Serras, Cayetano Gonzalez
Publikováno v:
Cells, Vol 11, Iss 16, p 2542 (2022)
The loss-of-function conditions for an l(3)malignant brain tumour (l(3)mbt) in larvae reared at 29 °C results in malignant brain tumours and hyperplastic imaginal discs. Unlike the former that have been extensively characterised, little is known abo
Externí odkaz:
https://doaj.org/article/8126ec23673648629e81f53bbf94e390
Publikováno v:
Cells, Vol 9, Iss 8, p 1842 (2020)
We have undertaken a study towards understanding the effect of ectopic expression of testis proteins in the soma in Drosophila. Here, we show that in the larval neuroepithelium, ectopic expression of the germline-specific component of the inner mitoc
Externí odkaz:
https://doaj.org/article/e5d752e3da404fac9a7d575c4f9025e2
Autor:
Cristina Molnar, Jose Reina, Anastasia Herrero, Jan Peter Heinen, Victoria Méndiz, Sophie Bonnal, Manuel Irimia, María Sánchez-Jiménez, Sara Sánchez-Molina, Jaume Mora, Cayetano Gonzalez
Publikováno v:
PNAS Nexus. 1
Ewing sarcoma (EwS) is a human malignant tumor typically driven by the Ewing sarcoma-Friend leukemia integration (EWS-FLI) fusion protein. A paucity of genetically modified animal models, partially owed to the high toxicity of EWS-FLI, hinders resear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1622fce07fba9265401e0bb5fb1a413c
https://doi.org/10.1093/pnasnexus/pgac222
https://doi.org/10.1093/pnasnexus/pgac222
Autor:
Fabrizio Rossi, Cristina Molnar, Kazuya Hashiyama, Jan P. Heinen, Judit Pampalona, Salud Llamazares, José Reina, Tomomi Hashiyama, Madhulika Rai, Giulia Pollarolo, Ismael Fernández-Hernández, Cayetano Gonzalez
Publikováno v:
Open Biology, Vol 7, Iss 8 (2017)
Using transgenic RNAi technology, we have screened over 4000 genes to identify targets to inhibit malignant growth caused by the loss of function of lethal(3)malignant brain tumour in Drosophila in vivo. We have identified 131 targets, which belong t
Externí odkaz:
https://doaj.org/article/25358b4aa1e74803859f0bca7f6ea9ca
Autor:
Cayetano Gonzalez
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Universidad de Barcelona
Asymmetric cell division (ACD) is a strategy for achieving cell diversity. Research carried out over the last two decades has shown that in some cell types that divide asymmetrically, mother and daughter centrosomes are noticeably different from one
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00bfbd3da25f229167aff13a9b04f3aa
https://doi.org/10.1016/j.sbi.2020.10.023
https://doi.org/10.1016/j.sbi.2020.10.023
Autor:
Alix Goupil, Jan Peter Heinen, Riham Salame, Fabrizio Rossi, Jose Reina, Carole Pennetier, Anthony Simon, Patricia Skorski, Anxela Louzao, Allison J. Bardin, Renata Basto, Cayetano Gonzalez
Publikováno v:
Development (Cambridge, England). 149(22)
While testing for genome instability in Drosophila as reported by unscheduled upregulation of UAS-GFP in cells that co-express GAL80 and GAL4, we noticed that, as expected, background levels were low in most developing tissues. However, GFP-positive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ce013e94d674c5eb29fdb415deb40b6
https://pubmed.ncbi.nlm.nih.gov/36399062
https://pubmed.ncbi.nlm.nih.gov/36399062
Autor:
Skorski P, Bardin A, Carole Pennetier, Lauzao A, Anthony Simon, Fabrizio Rossi, Alix Goupil, Cayetano Gonzalez, Heinen Jp, Salame R, Renata Basto
With the aim of developing a genetic instability (GI) sensor in vivo we used the well-established Gal80/Gal4-UAS system combined with a visual GFP marker in Drosophila. We generated a collection of 25 Drosophila lines carrying GAL80 transgenes in dif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22a94bfac5412e5863fc32ee0c9b5428
https://hal.archives-ouvertes.fr/hal-03453007
https://hal.archives-ouvertes.fr/hal-03453007
