Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Cay Egan"'
Autor:
A.-D. Yang, Anthony M. Magliocco, Cay Egan, S. Parkin, R. Singh, Brant Pohorelic, Konstantin Koro
Publikováno v:
Breast Cancer Research and Treatment. 133:201-214
The preferential metastasis of breast cancer cells to bone comprises a complex set of events including homing and preferential growth, which may require unique factors produced by bone or other cells in the immediate microenvironment. In this study,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d00fbb8f6a6fa0c396c2688787858d6
https://doi.org/10.1007/s10549-011-1753-2
https://doi.org/10.1007/s10549-011-1753-2
Autor:
Cay Egan, Patrick W. K. Lee, Peter A. Forsyth, Stefan J. Urbanski, Tommy Alain, Manbok Kim, Randal N. Johnston
Publikováno v:
Oncogene. 26:4124-4134
Reovirus shows considerable potential as an oncolytic agent for Ras-activated tumors and is currently in clinical trials. Here we ask whether such tumor cell lines can acquire resistance to reoviral oncolysis. We challenged human HT1080 fibrosarcoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06c4df1f9e5162eec957098bb0106e25
https://doi.org/10.1038/sj.onc.1210189
https://doi.org/10.1038/sj.onc.1210189
Publikováno v:
BioMed Research International, Vol 2015 (2015)
BioMed Research International
BioMed Research International
Murine models for the study of lung cancer have historically been the backbone of preliminary preclinical data to support early human clinical trials. However, the availability of multiple experimental systems leads to debate concerning which model,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::13faa0fd408c6c744634284ee33b4e54
https://doaj.org/article/31dbb60fdab744c2ba78a94aa11be728
https://doaj.org/article/31dbb60fdab744c2ba78a94aa11be728
Publikováno v:
Oncogene. 18:1227-1237
Elevated levels of Src kinase activity have been reported in a number of human cancers, including colon and breast cancer. We have analysed four human breast tumor cell lines that exhibit high levels of Src kinase activity, and have determined that t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19660def0e3d2b5bc12e360e8542b15b
https://doi.org/10.1038/sj.onc.1202233
https://doi.org/10.1038/sj.onc.1202233
Publikováno v:
Developmental Biology. 170:397-419
The Caenorhabditis elegans ges-1 gene (gut es terase No. 1 ) is expressed only in the intestinal lineage, beginning when the developing gut has only four to eight cells. We analyze the sequence requirements for this tissue-specific gene regulation by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bedf7811667c4da1df0ea78fe70bdda7
https://doi.org/10.1006/dbio.1995.1225
https://doi.org/10.1006/dbio.1995.1225
Autor:
Florence Boutillon, Don Morris, Alexander C. Klimowicz, Jinghui Hu, Angela Chan, Anthony M. Magliocco, Amanda Forsyth, Ashley Sutherland, Li Cai, Laurel Grant, Jae K. Lee, Yingying Cong, Patricia A. Tang, Carrie S. Shemanko, Vincent Goffin, Cay Egan, Tzu-Hua Juan, Stephanie K. Petrillo
Publikováno v:
Molecular Cancer Research. 14:B56-B56
The hormones prolactin (PRL), estrogen and progesterone have long been studied for their role in the primary breast tumor but not yet in modulating the secondary tumor microenvironment of the bone. Metastasis to the bone is a debilitating aspect of m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::feb0b0285a76d86dea855be95c5a296c
https://doi.org/10.1158/1557-3125.advbc15-b56
https://doi.org/10.1158/1557-3125.advbc15-b56
Autor:
Cay Egan, Anthony M. Magliocco
Publikováno v:
Breast Cancer-Focusing Tumor Microenvironment, Stem cells and Metastasis
Worldwide, breast cancer is the most frequent cancer diagnosed in women and is the second-most leading cause of cancer related deaths in women (Jemal, Bray et al. 2011). Death from breast cancer is most often the result of the spread of the primary t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c017abd03ab65def7e8392232de40a80
http://www.intechopen.com/articles/show/title/breast-cancer-metastasis-advances-through-the-use-of-in-vitro-co-culture-model-systems
http://www.intechopen.com/articles/show/title/breast-cancer-metastasis-advances-through-the-use-of-in-vitro-co-culture-model-systems
Autor:
Cay Egan, Brant Pohorelic, An-Dao Yang, Aru Narendran, Anthony M. Magliocco, Stephen Parkin, Konstantin Koro
Publikováno v:
Breast cancer research and treatment. 126(1)
The preferential metastasis of breast cancer cells to bone is a complex set of events including homing and preferential growth which may include unique factors produced by bone cells in the immediate microenvironment. In this study, we evaluated the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22d0bde1d1e0c79a022ee450d01d0620
https://pubmed.ncbi.nlm.nih.gov/20401631
https://pubmed.ncbi.nlm.nih.gov/20401631
Autor:
Cay Egan, Jae K. Lee, Amanda Forsyth, Patricia A. Tang, Carrie S. Shemanko, Tzu-Hua Juan, Alexander C. Klimowicz, Florence Boutillon, Li Cai, Don Morris, Anthony M. Magliocco, Laurel Grant, Stephanie K. Petrillo, Angela Chan, Yingying Cong, Vincent Goffin, Jinghui Hu, Ashley Sutherland
Publikováno v:
Journal of the National Cancer Institute. 108:djv338
Background Metastasis to the bone is a deleterious aspect of breast cancer and is a preferred site that results in bone loss. Hormones such as prolactin (PRL) have not yet been studied for their role in modulating the secondary tumor bone microenviro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75bb0b71bfa91b8e09165371476eacf5
https://doi.org/10.1093/jnci/djv338
https://doi.org/10.1093/jnci/djv338
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 87(15)
Previous work has suggested that oncogenic transformation by the E1A gene products of adenovirus type 5 may be mediated through interactions with at least two cellular proteins, the 105-kDa product of the retinoblastoma growth suppressor gene (p105-R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b787e6d41160194ad24f3f105b06eb5f
https://pubmed.ncbi.nlm.nih.gov/2143024
https://pubmed.ncbi.nlm.nih.gov/2143024