Zobrazeno 1 - 10
of 312
pro vyhledávání: '"Cav2.2"'
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
Ziconotide is a non-opioid analgesic that acts on N-type voltage-gated calcium channels. Despite its proven effectiveness in pain treatment, it can induce neuropsychiatric symptoms. The aim of this article is to present a case of psychosis secondary
Externí odkaz:
https://doaj.org/article/08ed5f766dc94ea689fb36b38e035323
Autor:
Keliang Chen, Tao Wang, Yong Li, Jun Wu, Cheng-Xiao Zhao, Sheng Liu, Fengrun Sun, Yehong Fang, Jiahuan Hu, Jinping Hu, Chong-Jing Zhang, Haibo Yu, Chao Ma, Shi-Shan Yu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 3, Pp 1326-1336 (2023)
Neuropathic pain is a chronic disease that severely afflicts the life and emotional status of patients, but currently available treatments are often ineffective. Novel therapeutic targets for the alleviation of neuropathic pain are urgently needed. R
Externí odkaz:
https://doaj.org/article/fa78e52e0ce74d39972af5bf1b1d66c3
Autor:
Mohammad Keimasi, Kowsar Salehifard, Noushin Mirshah Jafar Esfahani, Fariba Esmaeili, Arman Farghadani, Mohammadreza Amirsadri, Mohammadjavad Keimasi, Maryam Noorbakhshnia, Majid Moradmand, Mohammad Reza Mofid
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
The hippocampus is a complex area of the mammalian brain and is responsible for learning and memory. The trisynaptic circuit engages with explicit memory. Hippocampal neurons express two types of presynaptic voltage-gated calcium channels (VGCCs) com
Externí odkaz:
https://doaj.org/article/8ebe6565101b42b6a3b37221a32c56bf
Autor:
Mohammad Keimasi, Kowsar Salehifard, Mohammadjavad Keimasi, Mohammadreza Amirsadri, Noushin Mirshah Jafar Esfahani, Majid Moradmand, Fariba Esmaeili, Mohammad Reza Mofid
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
Externí odkaz:
https://doaj.org/article/e6eb445d7fa543f1b30eec2cf5a08e9c
Autor:
Mohammad Keimasi, Kowsar Salehifard, Mohammadjavad Keimasi, Mohammadreza Amirsadri, Noushin Mirshah Jafar Esfahani, Majid Moradmand, Fariba Esmaeili, Mohammad Reza Mofid
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
Excitotoxicity is a common pathological process in Alzheimer’s disease (AD) which is caused by the over-activity of N-Methyl-D-Aspartate receptors (NMDARs). The release of neurotransmitters depends on the activity of voltage-gated calcium channels
Externí odkaz:
https://doaj.org/article/d30c6d352d2f4d6aba67f8c871a41dbd
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Cyclovirobuxine D (CVB-D), the main active constituent of traditional Chinese medicine Buxus microphylla, was developed as a safe and effective cardiovascular drug in China. B. microphylla has also been used to relieve various pain symptoms for centu
Externí odkaz:
https://doaj.org/article/1344a5797a4b418586fce46be13a7821
Autor:
Flavia Tasmin Techera Antunes, Alessandra Hubner De Souza, Juliana Figueira, Nancy Scardua Binda, Vanice Paula Ricardo Carvalho, Luciene Bruno Vieira, Marcus Vinícius Gomez
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Calcium (Ca 2+) is an important second messenger in charge of many critical processes in the central nervous system (CNS), including membrane excitability, neurotransmission, learning, memory, cell proliferation, and apoptosis. In this way, the volta
Externí odkaz:
https://doaj.org/article/df14e25c66bd437c87e45789173b79c6
Akademický článek
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Akademický článek
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Publikováno v:
Computational and Structural Biotechnology Journal, Vol 18, Iss , Pp 2357-2372 (2020)
Chronic neuropathic pain is the most complex and challenging clinical problem of a population that sets a major physical and economic burden at the global level. Ca2+-permeable channels functionally orchestrate the processing of pain signals. Among t
Externí odkaz:
https://doaj.org/article/11561b78a9574d41ac479a0b4229f501