Zobrazeno 1 - 10
of 601
pro vyhledávání: '"Cav1"'
Autor:
Metha Yaikwaong, Pornpimon Ek-eudomsuk, Gunya Sittithumcharee, Vipavee Anupunpisit, Thavatchai Peerapatdit, Chaicharn Deerochanawong, Thep Himathongkam, Siwanon Jirawatnotai, Somlak Chuengsamarn
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract This study investigated the associations between CAV1 variants and metabolic syndrome (MetS), type 2 diabetes mellitus (T2DM), and cardiometabolic risk factors, as well as the influence of CAV1 variants on CAV1 mRNA expression. We genotyped
Externí odkaz:
https://doaj.org/article/e30bceb4596c400b832c52c680c691c0
Publikováno v:
Heliyon, Vol 10, Iss 21, Pp e38523- (2024)
Background: As the most common primary malignant bone tumor in children and adolescents, osteosarcoma currently lacks an effective clinical cure. Focal adhesion plays a crucial role in tumor invasion, migration, and drug resistance by mediating commu
Externí odkaz:
https://doaj.org/article/4091413eece7451aba08693a3f92a4f2
Autor:
Wenhong Liu, Guanghua Luo
Publikováno v:
Translational Oncology, Vol 50, Iss , Pp 102149- (2024)
Breast cancer is the most prevalent malignancy among women worldwide, with breast cancer stem cells (BCSCs) being the primary drivers of metastasis and recurrence. Numerous studies have elucidated the relationship between ferroptosis and cellular ste
Externí odkaz:
https://doaj.org/article/c2b1871316784c7a8486c09c63073e4b
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
In recent years, protein homeostasis imbalance caused by endoplasmic reticulum stress has become a major hallmark of cancer. Studies have shown that endoplasmic reticulum stress is closely related to the occurrence, development, and drug resistance o
Externí odkaz:
https://doaj.org/article/31d2b97d215e41bda6cbb6e7fe2ee83a
Publikováno v:
Discover Oncology, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Prostate cancer is the second incidence of malignant tumors in men worldwide. Its incidence and mortality are increasing year by year. Enhanced expression of Cav1 in prostate cancer has been linked to both proliferation and metastasis of can
Externí odkaz:
https://doaj.org/article/a04868fdc164459dad85f023143bd5ee
Autor:
Yu’e Liu, Yi Chen, Fei Wang, Jianghua Lin, Xiao Tan, Chao Chen, Lei-lei Wu, Xiaoling Zhang, Yi Wang, Yufeng Shi, Xiaoli Yan, Kaijun Zhao
Publikováno v:
Discover Oncology, Vol 14, Iss 1, Pp 1-23 (2023)
Abstract Background Glioma is a lethal brain cancer and lacking effective therapies. Challenges include no effective therapeutic target, intra- and intertumoral heterogeneity, inadequate effective drugs, and an immunosuppressive microenvironment, etc
Externí odkaz:
https://doaj.org/article/5c1fd379634547b9b07b2c06d5ad2616
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 6, Pp 4850-4874 (2023)
The high morbidity and mortality rate of pulmonary arterial hypertension (PAH) is partially explained by metabolic deregulation. The present study complements our previous publication in “Genes” by identifying significant increases of the glucose
Externí odkaz:
https://doaj.org/article/6ca1675324ab4d858c75a100eb531ed8
Akademický článek
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Autor:
Lucija Škara, Tonći Vodopić, Ivan Pezelj, Irena Abramovic, Borna Vrhovec, Alen Vrtarić, Nino Sincic, Davor Tomas, Stela Bulimbašić, Tomislav Kuliš, Monika Ulamec
Publikováno v:
Biomolecules & Biomedicine, Vol 23, Iss 1 (2023)
High prevalence and mortality of prostate cancer (PCa) are well known global health issues. Novel biomarkers for better identifying patients with PCa are the subject of extensive research. Prostate specific antigen (PSA) shows low specificity in scre
Externí odkaz:
https://doaj.org/article/3333f29df58c485f969e8a9aa0bf62b7
Autor:
Yin Shi, Zu Ye, Guang Lu, Naidi Yang, Jianbin Zhang, Liming Wang, Jianzhou Cui, Miguel A. del Pozo, Yihua Wu, Dajing Xia, Han-Ming Shen
Publikováno v:
Molecular Therapy: Oncolytics, Vol 23, Iss , Pp 311-329 (2021)
Drug resistance has become one of the largest challenges for cancer chemotherapies. Under certain conditions, cancer cells hijack autophagy to cope with therapeutic stress, which largely undermines the chemo-therapeutic efficacy. Currently, biomarker
Externí odkaz:
https://doaj.org/article/784d7619203943aa977f70f75746777f