Zobrazeno 1 - 10
of 482
pro vyhledávání: '"Cav-1"'
Autor:
Yingxue Li, Ying Wang, Qian Liu, Shuiying Lv, Yali Wang, Huanhuan Zhang, Qiuhong Zhao, Lei Shang
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 19, Iss 1, Pp 1-10 (2024)
Abstract Objective Our study focused on the effects and molecular mechanisms of kaempferol, a major active component of Eucommia ulmoides Oliver (EUO), on the osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs). Methods Target mo
Externí odkaz:
https://doaj.org/article/2fc1277b2f0848c1a9ba97fd343a54e7
Autor:
Di Wu, Kaiwen Zheng, Wenjing Yin, Bin Hu, Mingzhao Yu, Qingxiao Yu, Xiaojuan Wei, Jue Deng, Changqing Zhang
Publikováno v:
Bioactive Materials, Vol 36, Iss , Pp 317-329 (2024)
The integrative regeneration of both articular cartilage and subchondral bone remains an unmet clinical need due to the difficulties of mimicking spatial complexity in native osteochondral tissues for artificial implants. Layer-by-layer fabrication s
Externí odkaz:
https://doaj.org/article/cfeb21017b8d4dde8653f4180c53900f
Autor:
Ping Li, Hanying Zhou, Ran Yan, Wei Yan, Lu Yang, Tingting Li, Xiang Qin, Yanyan Zhou, Li Li, Ji Bao, Junjie Li, Shun Li, Yiyao Liu
Publikováno v:
Materials Today Bio, Vol 28, Iss , Pp 101245- (2024)
Tumorigenesis and metastasis are highly dependent on the interactions between the tumor and the surrounding microenvironment. In 3D matrix, the fibrous structure of the extracellular matrix (ECM) undergoes dynamic remodeling during tumor progression.
Externí odkaz:
https://doaj.org/article/a88aa49272b141eb8829ff2116df1977
Autor:
Tianliang Li, Bing Xu, Wenqian Li, Xiaotao Cheng, Wenjing Tantai, Haiyan Zheng, Liming Zhao, Nan Li, Chaofeng Han
Publikováno v:
Pharmacological Research, Vol 201, Iss , Pp 107096- (2024)
The uncontrolled bacterial infection-induced cytokine storm and sequential immunosuppression are commonly observed in septic patients, which indicates that the activation of phagocytic cells and the efficient and timely elimination of bacteria are cr
Externí odkaz:
https://doaj.org/article/1abd5412460a47f797c90c078d2b9835
Autor:
Yixin Wang, Mahmoud Halawa, Anupriya Chatterjee, Rachana Eshwaran, Yi Qiu, Yohanes Cakrapradipta Wibowo, Jianyuan Pan, Thomas Wieland, Yuxi Feng
Publikováno v:
Molecular Medicine, Vol 29, Iss 1, Pp 1-18 (2023)
Abstract Background Caveolin-1 (Cav-1) is a pivotal protein in the plasma membrane. Studies on homozygous Cav-1 deficient mice revealed that Cav-1 is essential for endothelial function and angiogenesis in the retina. However, whether a reduction in C
Externí odkaz:
https://doaj.org/article/eda3dbc86bfb479faf93f75bdb7ca7e6
Publikováno v:
Open Life Sciences, Vol 18, Iss 1, Pp 106535-48 (2023)
Externí odkaz:
https://doaj.org/article/e86e7e39683a44bca0005b9005659b10
Autor:
Tiantian Cui, Sergio Corrales-Guerrero, Veronica Castro-Aceituno, Sindhu Nair, Daniel C. Maneval, Curtis Monnig, Patrick Kearney, Sam Ellis, Nicholas Raheja, Neil Raheja, Terence M. Williams
Publikováno v:
Molecular Therapy: Oncolytics, Vol 30, Iss , Pp 181-192 (2023)
Albumin is an attractive candidate carrier for the development of novel therapeutic drugs. Gemcitabine has been FDA approved for the treatment of solid tumors; however, new drugs that optimize gemcitabine delivery are not available for clinical use.
Externí odkaz:
https://doaj.org/article/082c3e3a95e54afc8d405e1d14c0a9ab
Publikováno v:
Heliyon, Vol 10, Iss 2, Pp e24464- (2024)
Glioma is typically characterized by a poor prognosis and is associated with a decline in the quality of life as the disease advances. However, the development of effective therapies for glioma has been inadequate. Caveolin-1 (CAV-1) is a membrane pr
Externí odkaz:
https://doaj.org/article/f48f4c468383496d881d2478477fa1c5
Autor:
Ygor Marinho, Elizabeth S. Villarreal, Sammy Y. Aboagye, David L. Williams, Jun Sun, Claudia L. M. Silva, Sarah E. Lutz, Suellen D. Oliveira
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Schistosomiasis-associated Pulmonary Arterial Hypertension (Sch-PAH) is a life-threatening complication of chronic S. mansoni infection that can lead to heart failure and death. During PAH, the expansion of apoptosis-resistant endothelial cells (ECs)
Externí odkaz:
https://doaj.org/article/82466b06107d45c1b4e65f8c7c13f462
Autor:
Leila Elisa Gartner, Meriane Demoliner, Viviane Girardi, Kelen Gras de Oliveira, Fernanda Gil de Souza, Andréia Henzel
Publikováno v:
Water Policy, Vol 24, Iss 12, Pp 1827-1841 (2022)
The presence of coliforms, Mastadenovirus (AdV), and Canine protoparvovirus (CPV) in an Environmental Education Center, which contains city kennel, was investigated. Surface water and wastewater, dogs’ stool, and lettuce samples were collected from
Externí odkaz:
https://doaj.org/article/d5e7107d51c94768bb31ce9f88f7345b