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Adoptive T cell therapy of solid tumors: time to team up with immunogenic chemo/radiotherapy.

Autor: Pocaterra A; Lymphocyte Activation Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Via Olgettina, 58, 20132, Milan, Italy., Catucci M; Lymphocyte Activation Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Via Olgettina, 58, 20132, Milan, Italy., Mondino A; Lymphocyte Activation Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Via Olgettina, 58, 20132, Milan, Italy. Electronic address: anna.mondino@hsr.it.

Publikováno v: Current opinion in immunology [Curr Opin Immunol] 2022 Feb; Vol. 74, pp. 53-59. Date of Electronic Publication: 2021 Nov 04.

Reconstitution of a functional human thymus by postnatal stromal progenitor cells and natural whole-organ scaffolds.

Autor: Campinoti S; Epithelial Stem Cell Biology & Regenerative Medicine laboratory, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.; UCL Great Ormond Street Institute of Child Health, 30 Guilford Street, London, WC1N 1EH, UK., Gjinovci A; Epithelial Stem Cell Biology & Regenerative Medicine laboratory, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.; Institute of Immunity & Transplantation, Division of Infection & Immunity, UCL, Royal Free Hospital, London, NW3 2PF, UK., Ragazzini R; Epithelial Stem Cell Biology & Regenerative Medicine laboratory, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.; Institute of Immunity & Transplantation, Division of Infection & Immunity, UCL, Royal Free Hospital, London, NW3 2PF, UK., Zanieri L; Epithelial Stem Cell Biology & Regenerative Medicine laboratory, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.; Institute of Immunity & Transplantation, Division of Infection & Immunity, UCL, Royal Free Hospital, London, NW3 2PF, UK., Ariza-McNaughton L; Haematopoietic Stem Cell laboratory, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK., Catucci M; Epithelial Stem Cell Biology & Regenerative Medicine laboratory, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.; UCL Great Ormond Street Institute of Child Health, 30 Guilford Street, London, WC1N 1EH, UK.; Division of Immunology, Transplantation and Infectious Diseases, San Raffaele Scientific Institute, DIBIT 20132, Milan, Italy., Boeing S; Bioinformatics Laboratory, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK., Park JE; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK.; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, Republic of Korea., Hutchinson JC; UCL Great Ormond Street Institute of Child Health, 30 Guilford Street, London, WC1N 1EH, UK.; Department of Histopathology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, WC1N 1EH, UK., Muñoz-Ruiz M; Immunosurveillance laboratory, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK., Manti PG; Department of Experimental Oncology, IEO, European Institute of Oncology, IRCCS, Milan, Italy.; Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy., Vozza G; Department of Experimental Oncology, IEO, European Institute of Oncology, IRCCS, Milan, Italy.; Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy., Villa CE; Department of Experimental Oncology, IEO, European Institute of Oncology, IRCCS, Milan, Italy., Phylactopoulos DE; Epithelial Stem Cell Biology & Regenerative Medicine laboratory, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.; UCL Great Ormond Street Institute of Child Health, 30 Guilford Street, London, WC1N 1EH, UK., Maurer C; Epithelial Stem Cell Biology & Regenerative Medicine laboratory, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.; UCL Great Ormond Street Institute of Child Health, 30 Guilford Street, London, WC1N 1EH, UK., Testa G; Department of Experimental Oncology, IEO, European Institute of Oncology, IRCCS, Milan, Italy.; Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy., Stauss HJ; Institute of Immunity & Transplantation, Division of Infection & Immunity, UCL, Royal Free Hospital, London, NW3 2PF, UK., Teichmann SA; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK., Sebire NJ; UCL Great Ormond Street Institute of Child Health, 30 Guilford Street, London, WC1N 1EH, UK.; Department of Histopathology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, WC1N 1EH, UK., Hayday AC; Immunosurveillance laboratory, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.; Peter Gorer Department of Immunobiology, School of Immunology & Microbial Sciences, King's College London, London, UK., Bonnet D; Haematopoietic Stem Cell laboratory, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK., Bonfanti P; Epithelial Stem Cell Biology & Regenerative Medicine laboratory, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK. p.bonfanti@ucl.ac.uk.; UCL Great Ormond Street Institute of Child Health, 30 Guilford Street, London, WC1N 1EH, UK. p.bonfanti@ucl.ac.uk.; Institute of Immunity & Transplantation, Division of Infection & Immunity, UCL, Royal Free Hospital, London, NW3 2PF, UK. p.bonfanti@ucl.ac.uk.

Publikováno v: Nature communications [Nat Commun] 2020 Dec 11; Vol. 11 (1), pp. 6372. Date of Electronic Publication: 2020 Dec 11.

Tviblindi algorithm identifies branching developmental trajectories of human B-cell development and describes abnormalities in RAG-1 and WAS patients.

Autor: Bakardjieva M; CLIP, Department of Paediatric Haematology and Oncology, Second Faculty of Medicine, Charles University, Prague, Czech Republic., Pelák O; CLIP, Department of Paediatric Haematology and Oncology, Second Faculty of Medicine, Charles University, Prague, Czech Republic., Wentink M; Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., Glier H; CLIP, Department of Paediatric Haematology and Oncology, Second Faculty of Medicine, Charles University, Prague, Czech Republic., Novák D; CLIP, Department of Paediatric Haematology and Oncology, Second Faculty of Medicine, Charles University, Prague, Czech Republic.; Department of Applied Mathematics, Computer Science and Statistics, Ghent University, Ghent, Belgium.; Data Mining and Modeling for Biomedicine, Center for Inflammation Research, VIB-UGent, Ghent, Belgium., Stančíková J; CLIP, Department of Paediatric Haematology and Oncology, Second Faculty of Medicine, Charles University, Prague, Czech Republic., Kužílková D; CLIP, Department of Paediatric Haematology and Oncology, Second Faculty of Medicine, Charles University, Prague, Czech Republic.; Department of Paediatric Haematology and Oncology, University Hospital Motol, Prague, Czech Republic., Mejstříková E; CLIP, Department of Paediatric Haematology and Oncology, Second Faculty of Medicine, Charles University, Prague, Czech Republic.; Department of Paediatric Haematology and Oncology, University Hospital Motol, Prague, Czech Republic., Janowska I; Department of Rheumatology and Clinical Immunology, Freiburg University Medical Center, University of Freiburg, Freiburg, Germany.; Center for Chronic Immunodeficiency, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Rizzi M; Department of Rheumatology and Clinical Immunology, Freiburg University Medical Center, University of Freiburg, Freiburg, Germany.; Center for Chronic Immunodeficiency, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., van der Burg M; Department of Pediatrics, Laboratory for Pediatric Immmunology, Leiden University Medical Center, Leiden, the Netherlands., Stuchlý J; CLIP, Department of Paediatric Haematology and Oncology, Second Faculty of Medicine, Charles University, Prague, Czech Republic.; Department of Paediatric Haematology and Oncology, University Hospital Motol, Prague, Czech Republic., Kalina T; CLIP, Department of Paediatric Haematology and Oncology, Second Faculty of Medicine, Charles University, Prague, Czech Republic.; Department of Paediatric Haematology and Oncology, University Hospital Motol, Prague, Czech Republic.

Publikováno v: European journal of immunology [Eur J Immunol] 2024 Sep 05, pp. e2451004. Date of Electronic Publication: 2024 Sep 05.