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Deregulation of JAK2 signaling underlies primary cutaneous CD8(+) aggressive epidermotropic cytotoxic T-cell lymphoma

Autor: Torres, A.N.B., Cats, D., Out-Luiting, J.J., Fanoni, D., Mei, H.L., Venegoni, L., Willemze, R., Vermeer, M.H., Berti, E., Tensen, C.P.

Publikováno v: Haematologica, 107(3), 702-714. FERRATA STORTI FOUNDATION

Primary cutaneous CD8(+) aggressive epidermotropic cytotoxic T-cell lymphoma (pcAECyTCL) is a rare variant of cutaneous T-cell lymphoma with an aggressive clinical course and a very poor prognosis. Until now, neither a systematic characterization of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::06bebfa8fa3b192b6780ee55918c4d42
http://hdl.handle.net/1887/3564007

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Genetics and Not Shared Environment Explains Familial Resemblance in Adult Metabolomics Data

Autor: Pool, Rene, Hagenbeek, Fiona A., Hendriks, Anne M., van Dongen, Jenny, Willemsen, Gonneke, de Geus, Eco, van Dijk, Ko Willems, Verhoeven, Aswin, Suchiman, H. Eka, Beekman, Marian, Slagboom, P. Eline, Harms, Amy C., Hankemeier, Thomas, Boomsma, Dorret, I, Beekman, M., Suchiman, H. E. D., Amin, N., Beulens, J. W., van der Bom, J. A., Bomer, N., Demirkan, A., van Hilten, J. A., Meessen, J. M. T. A., Pool, R., Moed, M. H., Fu, J., Onderwater, G. L. J., Rutters, F., So-Osman, C., van der Flier, W. M., van der Heijden, A. A. W. A., van der Spek, A., Asselbergs, F. W., Boersma, E., Elders, P. M., Geleijnse, J. M., Ikram, M. A., Kloppenburg, M., Meulenbelt, I, Mooijaart, S. P., Nelissen, R. G. H. H., Netea, M. G., Penninx, B. W. J. H., Stehouwer, C. D. A., Teunissen, C. E., Terwindt, G. M., 't Hart, L. M., van den Maagdenberg, A. M. J. M., van der Harst, P., van der Horst, I. C. C., van der Kallen, C. J. H., van Greevenbroek, M. M. J., van Spil, W. E., Wijmenga, C., Zwinderman, A. H., Zhernikova, A., Jukema, J. W., Wolf, J. J. H. Barkey, Cats, D., Mei, H., Slofstra, M., Swertz, M., van den Akker, E. B., Deelen, J., Reinders, M. J. T., Boomsma, D., I, van Duijn, C. M., Slagboom, P. E.

Publikováno v: Pool, R, Hagenbeek, F A, Hendriks, A M, van Dongen, J, Willemsen, G, de Geus, E, van Dijk, K W, Verhoeven, A, Suchiman, H E, Beekman, M, Slagboom, P E, Harms, A C, Hankemeier, T, Boomsma, D I, Beekman, M, Suchiman, H E D, Amin, N, Beulens, J W, van der Bom, J A, Bomer, N, Demirkan, A, van Hilten, J A, Meessen, J M T A, Pool, R, Moed, M H, Fu, J, Onderwater, G L J, Rutters, F, So-Osman, C, van der Flier, W M, van der Heijden, A A W A, van der Spek, A, Asselbergs, F W, Boersma, E, Elders, P M, Geleijnse, J M, Ikram, M A, Kloppenburg, M, Meulenbelt, I, Mooijaart, S P, Nelissen, R G H H, Netea, M G, Penninx, B W J H, Stehouwer, C D A, Teunissen, C E, Terwindt, G M, 't Hart, L M, van den Maagdenberg, A M J M, van der Harst, P, van der Horst, I C C, van der Kallen, C J H, van Greevenbroek, M M J, van Spil, W E, Wijmenga, C, Zwinderman, A H, Zhernikova, A, Jukema, J W, Wolf, J J H B, Cats, D, Mei, H, Slofstra, M, Swertz, M, van den Akker, E B, Deelen, J, Reinders, M J T, Boomsma, D I, van Duijn, C M, Slagboom, P E & BBMRI-NL Metabolomics Consortium 2020, ' Genetics and Not Shared Environment Explains Familial Resemblance in Adult Metabolomics Data ', Twin Research and Human Genetics, vol. 23, no. 3, pp. 145-155 . https://doi.org/10.1017/thg.2020.53
Twin Research and Human Genetics, 23(3):1832427420000535, 145-155. Australian Academic Press
Twin research and human genetics, 23(3), 145-155. Cambridge University Press
Twin Research and Human Genetics, 23(3), 145-155. CAMBRIDGE UNIV PRESS
Twin Research and Human Genetics, 23(3), 145-155. Australian Academic Press
Pool, R, Hagenbeek, F A, Hendriks, A M, Van Dongen, J, Willemsen, G, De Geus, E, Consortium, C M, Willems Van Dijk, K, Verhoeven, A, Suchiman, H E, Beekman, M, Slagboom, P E, Harms, A C, Hankemeier, T & Boomsma, D I 2020, ' Genetics and Not Shared Environment Explains Familial Resemblance in Adult Metabolomics Data ', Twin Research and Human Genetics, vol. 23, no. 3, pp. 145-155 . https://doi.org/10.1017/thg.2020.53
Twin Research and Human Genetics, 23, 3, pp. 145-155
Twin Research and Human Genetics, 23(3), 145-155. Cambridge University Press
Twin Research and Human Genetics, 23, 145-155

Metabolites are small molecules involved in cellular metabolism where they act as reaction substrates or products. The term ‘metabolomics’ refers to the comprehensive study of these molecules. The concentrations of metabolites in biological tissu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f13d7f35ebcb1876e9f91b2d6b8a7bf
https://hdl.handle.net/11370/b82ca290-c97f-470f-a253-e213a3cbee38

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Author Correction: Heritability estimates for 361 blood metabolites across 40 genome-wide association studies (Nature Communications, (2020), 11, 1, (39), 10.1038/s41467-019-13770-6)

Autor: Hagenbeek, Fiona A., Pool, René, van Dongen, Jenny, Draisma, H. M., Jan Hottenga, Jouke, Willemsen, Gonneke, Abdellaoui, Abdel, Fedko, Iryna O., den Braber, Anouk, Visser, Pieter Jelle, de Geus, Eco J.C.N., Willems van Dijk, Ko, Verhoeven, Aswin, Suchiman, H. Eka, Beekman, Marian, Slagboom, P. Eline, van Duijn, Cornelia M., Barkey Wolf, J. J.H., Cats, D., Amin, N., Beulens, J. W., van der Bom, J. A., Bomer, N., Demirkan, A., van Hilten, J. A., Meessen, J. M.T.A., Moed, M. H., Fu, J., Onderwater, G. L.J., Rutters, F., So-Osman, C., van der Flier, W. M., van der Heijden, A. A.W.A., van der Spek, A., Asselbergs, F. W., Boersma, E., Elders, P. M., Geleijnse, J. M., Ikram, M. A., Kloppenburg, M., Meulenbelt, I., Mooijaart, S. P., Nelissen, R. G.H.H., Netea, M. G., Penninx, B. W.J.H., Stehouwer, C. D.A., Teunissen, C. E., Terwindt, G. M., ‘t Hart, L. M., van den Maagdenberg, A. M.J.M., van der Harst, P., van der Horst, I. C.C., van der Kallen, C. J.H., van Greevenbroek, M. M.J., van Spil, W. E., Wijmenga, C., Zwinderman, A. H., Zhernikova, A., Jukema, J. W., Mei, H., Slofstra, M., Swertz, M., van den Akker, E. B., Deelen, J., Reinders, M. J.T., Harms, Amy C., Hankemeier, Thomas, Bartels, Meike, Nivard, Michel G., Boomsma, Dorret I.

Publikováno v: Nature Communications, 11(1):1702. Nature Publishing Group UK
Hagenbeek, F A, Pool, R, van Dongen, J, Draisma, H M, Jan Hottenga, J, Willemsen, G, Abdellaoui, A, Fedko, I O, den Braber, A, Visser, P J, de Geus, E J C N, Willems van Dijk, K, Verhoeven, A, Suchiman, H E, Beekman, M, Slagboom, P E, van Duijn, C M, Barkey Wolf, J J H, Cats, D, Amin, N, Beulens, J W, van der Bom, J A, Bomer, N, Demirkan, A, van Hilten, J A, Meessen, J M T A, Moed, M H, Fu, J, Onderwater, G L J, Rutters, F, So-Osman, C, van der Flier, W M, van der Heijden, A A W A, van der Spek, A, Asselbergs, F W, Boersma, E, Elders, P M, Geleijnse, J M, Ikram, M A, Kloppenburg, M, Meulenbelt, I, Mooijaart, S P, Nelissen, R G H H, Netea, M G, Penninx, B W J H, Stehouwer, C D A, Teunissen, C E, Terwindt, G M, ‘t Hart, L M, van den Maagdenberg, A M J M, van der Harst, P, van der Horst, I C C, van der Kallen, C J H, van Greevenbroek, M M J, van Spil, W E, Wijmenga, C, Zwinderman, A H, Zhernikova, A, Jukema, J W, Mei, H, Slofstra, M, Swertz, M, van den Akker, E B, Deelen, J, Reinders, M J T, Harms, A C, Hankemeier, T, Bartels, M, Nivard, M G, Boomsma, D I & BBMRI Metabolomics Consortium 2020, ' Author Correction : Heritability estimates for 361 blood metabolites across 40 genome-wide association studies (Nature Communications, (2020), 11, 1, (39), 10.1038/s41467-019-13770-6) ', Nature Communications, vol. 11, no. 1, 1702 . https://doi.org/10.1038/s41467-020-15276-y

The original version of the Supplementary Information associated with this Article included an incorrect Supplementary Data 1 file, in which additional delimiters were included in the first column for a number of rows, resulting in column shifts for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::ef3a5159eb95b733fb64bbe9b76a9a0a
https://research.vumc.nl/en/publications/141149d3-541f-49ab-8cfe-73d00eecd259

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Heritability estimates for 361 blood metabolites across 40 genome-wide association studies

Autor: Hagenbeek, F.A., Pool, R., Dongen, J. van, Draisma, H.H.M., Hottenga, J.J., Willemsen, G., Abdellaoui, A., Fedko, I.O., Braber, A. den, Visser, P.J., Geus, E.J.C.N. de, Dijk, K.W. van, Verhoeven, A., Suchiman, H.E., Beekman, M., Slagboom, P.E., Duijn, C.M. van, Harms, A.C., Hankemeier, T., Bartels, M., Nivard, M.G., Boomsma, D.I., Wolf, J.J.H.B., Cats, D., Amin, N., Beulens, J.W., Bom, J.A. van der, Bomer, N., Demirkan, A., Hilten, J.A. van, Meessen, J.M.T.A., Moed, M.H., Fu, J., Onderwater, G.L.J., Rutters, F., So-Osman, C., Flier, W.M. van der, Heijden, A.A.W.A. van der, Spek, A. van der, Asselbergs, F.W., Boersma, E., Elders, P.M., Geleijnse, J.M., Ikram, M.A., Kloppenburg, M., Meulenbelt, I., Mooijaart, S.P., Nelissen, R.G.H.H., Netea, M.G., Penninx, B.W.J.H., Stehouwer, C.D.A., Teunissen, C.E., Terwindt, G.M., Hart, L.M. 't, Maagdenberg, A.M.J.M. van den, Harst, P. van der, Horst, I.C.C. van der, Kallen, C.J.H. van der, Greevenbroek, M.M.J. van, Spil, W.E. van, Wijmenga, C., Zwinderman, A.H., Zhernikova, A., Jukema, J.W., Mei, H., Slofstra, M., Swertz, M., Akker, E.B. van den, Deelen, J., Reinders, M.J.T., BBMRI Metabolomics Consortium

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Nature Communications, 11(1):39. Nature Publishing Group
Nature Communications
Nature Communications, 11(1)
Nature Communications, 11, 1
Nature Communications, 11(1). NATURE PUBLISHING GROUP
Nature Communications 11 (2020) 1
Nature communications, 11(1):39. Nature Publishing Group
BBMRI Metabolomics Consortium 2020, ' Heritability estimates for 361 blood metabolites across 40 genome-wide association studies ', Nature Communications, vol. 11, no. 1, 39 . https://doi.org/10.1038/s41467-019-13770-6
Hagenbeek, F A, Pool, R, van Dongen, J, Draisma, H H M, Jan Hottenga, J, Willemsen, G, Abdellaoui, A, Fedko, I O, den Braber, A, de Geus, E J C N, Bartels, M, Nivard, M G, Boomsma, D I & BBMRI Metabolomics Consortium 2020, ' Heritability estimates for 361 blood metabolites across 40 genome-wide association studies ', Nature Communications, vol. 11, no. 1, 39, pp. 1-11 . https://doi.org/10.1038/s41467-019-13770-6
Nature Communications, 11
Nature Communications, 11(1):39, 1-11. Nature Publishing Group

Metabolomics examines the small molecules involved in cellular metabolism. Approximately 50% of total phenotypic differences in metabolite levels is due to genetic variance, but heritability estimates differ across metabolite classes. We perform a re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d602b66b28d0da3d11efa9557e2c947
https://hdl.handle.net/2066/216654

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