Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Catriona Charlton"'
Autor:
Jonathan M. Hazlehurst, Teegan Reina Lim, Catriona Charlton, Jack J. Miller, Laura L. Gathercole, Thomas Cornfield, Nikolaos Nikolaou, Shelley E. Harris, Ahmad Moolla, Nantia Othonos, Lisa C. Heather, Thomas Marjot, Damian J. Tyler, Carolyn Carr, Leanne Hodson, Jane McKeating, Jeremy W. Tomlinson
Publikováno v:
Metabolism Open, Vol 14, Iss , Pp 100177- (2022)
Background and aims: Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver condition. It is tightly associated with an adverse metabolic phenotype (including obesity and type 2 diabetes) as well as with obstructive sleep apnoea (
Externí odkaz:
https://doaj.org/article/4594b0aa997b40519a78b4393c21a3ac
Autor:
Leanne Hodson, Sion A. Parry, Thomas Cornfield, Catriona Charlton, Wee Suan Low, Charlotte J. Green, Fredrik Rosqvist
Publikováno v:
Upsala Journal of Medical Sciences, Vol 125, Iss 3, Pp 211-216 (2020)
Background: Hepatic de novo lipogenesis (DNL) is ideally measured in very low-density lipoprotein (VLDL)-triacylglycerol (TAG). In the fasting state, the majority of plasma TAG typically represents VLDL-TAG; however, the merits of measuring DNL in to
Externí odkaz:
https://doaj.org/article/1d2f612ccf0746d68d320dee8ba74e3a
Autor:
Thomas Pither, Lu Wang, Lucy Bates, Morvern Morrison, Catriona Charlton, Chelsea Griffiths, Jamie Macdonald, Venetia Bigley, Maria Mavridou, Joseph Barsby, Lee Borthwick, John Dark, William Scott, Simi Ali, Andrew J. Fisher
Publikováno v:
Transplantation.
Autor:
Charlotte J Green, Thomas Marjot, John Walsby-Tickle, Catriona Charlton, Thomas Cornfield, Felix Westcott, Katherine E Pinnick, Ahmad Moolla, Jonathan M Hazlehurst, James McCullagh, Jeremy W Tomlinson, Leanne Hodson
Objective Metformin is a first-line pharmacotherapy in the treatment of type 2 diabetes, a condition closely associated with non-alcoholic fatty liver disease (NAFLD). Although metformin promotes weight loss and improves insulin sensitivity, its effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e4ae4874c6c19249dd759fceb7e3d27
https://doi.org/10.1530/eje-21-0850
https://doi.org/10.1530/eje-21-0850
Autor:
John Robert Ferdinand, Morvern Isabel Morrison, Anders Andreasson, Catriona Charlton, Alisha Kaur Chhatwal, William Earl Scott, Lee Anthony Borthwick, Menna Ruth Clatworthy, Andrew J. Fisher
Publikováno v:
Clinical transplantation. 36(4)
Funder: NIHR Blood and Transplant Unit
Funder: NIHR Newcastle Biomedical Research Centre; Id: http://dx.doi.org/10.13039/501100012295
Funder: NIHR Cambridge Biomedical Research Centre; Id: http://dx.doi.org/10.13039/501100018956
BACKGR
Funder: NIHR Newcastle Biomedical Research Centre; Id: http://dx.doi.org/10.13039/501100012295
Funder: NIHR Cambridge Biomedical Research Centre; Id: http://dx.doi.org/10.13039/501100018956
BACKGR
Autor:
Catriona Charlton, Jeremy F. L. Cobbold, Ahmad Moolla, Jonathan Hazlehurst, Stefan Neubauer, Charlotte J. Green, Jane M Francis, Leanne Hodson, Thomas Cornfield, Sarah White, Jeremy W. Tomlinson, Thomas Marjot
Publikováno v:
JGH Open, Vol 4, Iss 3, Pp 433-440 (2020)
JGH Open: An Open Access Journal of Gastroenterology and Hepatology
JGH Open: An Open Access Journal of Gastroenterology and Hepatology
Background and Aim Non‐alcoholic fatty liver disease (NAFLD) is rapidly becoming the leading indication for liver transplant and is associated with increased cardiovascular and liver mortality, yet there are no licensed therapies. Sodium‐glucose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffd46d7226b1d9832fdb61b20054f6de
https://ora.ox.ac.uk/objects/uuid:de12813b-d160-4146-851f-eaeaa08861b2
https://ora.ox.ac.uk/objects/uuid:de12813b-d160-4146-851f-eaeaa08861b2
Autor:
Wee Suan Low, Siôn A Parry, Thomas Cornfield, Fredrik Rosqvist, Charlotte J. Green, Leanne Hodson, Catriona Charlton
Publikováno v:
Upsala Journal of Medical Sciences
Upsala Journal of Medical Sciences, Vol 125, Iss 3, Pp 211-216 (2020)
Upsala Journal of Medical Sciences, Vol 125, Iss 3, Pp 211-216 (2020)
Background: Hepatic de novo lipogenesis (DNL) is ideally measured in very low-density lipoprotein (VLDL)-triacylglycerol (TAG). In the fasting state, the majority of plasma TAG typically represents VLDL-TAG, however the merits of measuring DNL in tot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16e7826223eab9e306daca9516eae5e5
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-423847
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-423847
Autor:
Catriona Charlton, Camilla Pramfalk, Leanne Hodson, Pippa J. Gunn, Thomas Cornfield, Charlotte J. Green, Michael Pavalides, Fredrik Karpe
Publikováno v:
Endocrine Abstracts.
Autor:
Sebastian Munck, Kazuaki Yoshinaga, Mariia Yuneva, Gianmarco Rinaldi, Kwok-Kin Wong, Juan Fernández-García, Brandon Faubert, Chris Verslype, Thomas G. P. Grunewald, Sweta Parik, Mustapha Najimi, Catherine M. Verfaillie, Carmen Escalona-Noguero, Leanne Hodson, Kim Vriens, Sylvia Grünewald, Stefan Christen, Charlotte Kopitz, Catriona Charlton, Andrés Méndez-Lucas, Axelle Kerstens, Naohiro Gotoh, Matteo Rossi, Johannes V. Swinnen, David Cassiman, Arndt Schmitz, Laura Beretta, Ting Chen, Ruben Boon, Etienne Sokal, Patrick Steigemann, Andrea Hägebarth, Jonas Dehairs, Roberta Schmieder, Thomas Cornfield, Dorien Broekaert, Sarah-Maria Fendt, Jo A. Van Ginderachter, Martin F. Orth, Suet Ying Kwan, Laura Romero-Pérez, Sven Christian, Ali Talebi, Rita Derua, Ralph J. DeBerardinis, Joao A.G. Duarte
Publikováno v:
Nature
Most tumours have an aberrantly activated lipid metabolism1,2 that enables them to synthesize, elongate and desaturate fatty acids to support proliferation. However, only particular subsets of cancer cells are sensitive to approaches that target fatt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d4fabf9bd4ddc36b2d7b181be546e8e
https://doi.org/10.1038/s41586-019-0904-1
https://doi.org/10.1038/s41586-019-0904-1
Autor:
Michael Pavlides, Fredrik Karpe, Leanne Hodson, Pippa J. Gunn, Charlotte J. Green, Catriona Charlton, Camilla Pramfalk, Thomas Cornfield
Publikováno v:
BMJ Open Diabetes Research & Care
ObjectiveIncreased hepatic de novo lipogenesis (DNL) is suggested to be an underlying cause in the development of nonalcoholic fatty liver disease and/or insulin resistance. It is suggested that omega-3 fatty acids (FA) lower hepatic DNL. We investig