Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Catrina A. Reed"'
Autor:
Jeffery M. Tharp, J. Trae Hampton, Catrina A. Reed, Andreas Ehnbom, Peng-Hsun Chase Chen, Jared S. Morse, Yadagirri Kurra, Lisa M. Pérez, Shiqing Xu, Wenshe Ray Liu
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Most epigenetic regulator inhibitors target tunnels of active sites, rather than the peptide binding groove, leading to concerns with low selectivity. Here the authors use an amber obligate phage library to rapidly identify isoform-selective inhibito
Externí odkaz:
https://doaj.org/article/b1aac1c05c7c4fed851748bbcd7bc307
Autor:
J. Trae Hampton, Duen Shian Wang, Jin Liu, Wenshe R. Liu, Sukant K. Das, Jeffery M. Tharp, Xiaoshan Shayna Wang, Catrina A. Reed, Peng Hsun Chase Chen, Yang Shen, Hamed S. Hayatshahi
Publikováno v:
Angew Chem Int Ed Engl
Superior to linear peptides in biological activities, cyclic peptides are considered to have great potentials used as therapeutic agents. In order to identify cyclic peptide ligands for therapeutic targets, selection from phage-displayed peptide libr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afb35f4a61f551d4af12876361d84689
https://doi.org/10.1002/anie.201908713
https://doi.org/10.1002/anie.201908713
Autor:
Catrina A. Reed, Peng-Hsun Chase Chen, Jared S. Morse, Jeffery M. Tharp, J. Trae Hampton, Andreas Ehnbom, Yadagirri Kurra, Wenshe R. Liu, Shiqing Xu, Lisa M. Pérez
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications
Nature Communications
Although noncanonical amino acids (ncAAs) were first incorporated into phage libraries through amber suppression nearly two decades ago, their application for use in drug discovery has been limited due to inherent library bias towards sense-containin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef5ded75688845688a26eda79e158570
https://doi.org/10.1038/s41467-020-15057-7
https://doi.org/10.1038/s41467-020-15057-7
The capsids of ssRNA phages comprise a single copy of an ~45 kDa maturation protein that serves to recognize the conjugative pilus as receptor, to protect the ends of the viral RNA and also to escort the genomic RNA into the host cytoplasm. In the Al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e22a75b3471fd6a0cf5268c9b594c49a
https://europepmc.org/articles/PMC3709820/
https://europepmc.org/articles/PMC3709820/
Autor:
Sarah J. Mann, Chris J. Charlton, Catrina F. Reed, Joy Stevenson, Raymond Ransley, Paul R. Heaton, Brigitte H. E. Smith, E. Jean Harper, John M. Rawlings
Publikováno v:
The Journal of nutrition. 132(6 Suppl 2)
We studied the effects of feeding an antioxidant blend of vitamins, minerals and carotenoids to a mixed adult dog population (n = 40, mean 4.4 +/- 1.85 y) for a 16-wk period. Compared to the control group of dogs (n = 20), the antioxidant (AOX)-suppl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a12390d50d146486e8d7681000dfffdb
https://pubmed.ncbi.nlm.nih.gov/12042506
https://pubmed.ncbi.nlm.nih.gov/12042506