Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Catrina A. Chitjian"'
Autor:
Scarlett B. Ferguson, David H. Giles, Rebecca M. Wellmann, Kevin N. Dalby, Tamer S. Kaoud, Gabriel Stancu, Ranajeet Ghose, Catrina A. Chitjian, Clint D.J. Tavares
Publikováno v:
Journal of Biological Chemistry. 292:2032-2045
Eukaryotic elongation factor 2 kinase (eEF-2K), the only calmodulin (CaM)-dependent member of the unique α-kinase family, impedes protein synthesis by phosphorylating eEF-2. We recently identified Thr-348 and Ser-500 as two key autophosphorylation s
Publikováno v:
Cancer Biol Ther
Dichloroacetate (DCA) is an inhibitor of pyruvate dehydrogenase kinase (PDK) that has been shown to reverse the Warburg effect and cause tumor cell death. Clinical research into the anti-cancer activity of DCA revealed high dosage requirements and re
Autor:
Clint D J, Tavares, David H, Giles, Gabriel, Stancu, Catrina A, Chitjian, Scarlett B, Ferguson, Rebecca M, Wellmann, Tamer S, Kaoud, Ranajeet, Ghose, Kevin N, Dalby
Publikováno v:
The Journal of biological chemistry. 292(5)
Eukaryotic elongation factor 2 kinase (eEF-2K), the only calmodulin (CaM)-dependent member of the unique α-kinase family, impedes protein synthesis by phosphorylating eEF-2. We recently identified Thr-348 and Ser-500 as two key autophosphorylation s
Autor:
Pengyu Ren, James L. Bachman, Eric V. Anslyn, Qiantao Wang, Ramakrishna Edupuganti, Clint D.J. Tavares, Catrina A. Chitjian, Kevin N. Dalby
A small molecule library of pyrido[2,3-d]pyrimidine-2,4-dione derivatives 6–16 was synthesized from 6-amino-1,3-disubstituted uracils 18, characterized, and screened for inhibitory activity against eukaryotic elongation factor-2 kinase (eEF-2K). To
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::591317164e1f8c18429acf415d6a7c6c
https://europepmc.org/articles/PMC6473179/
https://europepmc.org/articles/PMC6473179/