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pro vyhledávání: '"Catrin Weiler"'
Autor:
Linda Ebertsch, Elisa Izaurralde, Lara Wohlbold, Cátia Igreja, Catrin Weiler, Ramona Weber, Oliver Weichenrieder, Daniel Peter
Publikováno v:
Molecular Cell. 57:1074-1087
The eIF4E-binding proteins (4E-BPs) represent a diverse class of translation inhibitors that are often deregulated in cancer cells. 4E-BPs inhibit translation by competing with eIF4G for binding to eIF4E through an interface that consists of canonica
Autor:
Mahendra Sonawane, Elisa Izaurralde, Catrin Weiler, Eric Huntzinger, Nadine Wittkopp, Jérôme Saulière, Steffen Schmidt
Publikováno v:
Molecular and Cellular Biology. 29:3517-3528
The nonsense-mediated mRNA decay (NMD) pathway promotes rapid degradation of mRNAs containing premature translation termination codons (PTCs or nonsense codons), preventing accumulation of potentially detrimental truncated proteins. In metazoa, seven
Autor:
Christiane Nüsslein-Volhard, Hans-Martin Maischein, Marcus P. S. Dekens, Catrin Weiler, Francisco Pelegri, Stefan Schulte-Merker
Publikováno v:
Developmental Dynamics. 231:324-335
In animal species, early developmental processes are driven by maternally derived factors. Here, we describe a forward genetics approach to identify recessive mutations in genes encoding such maternal factors in the zebrafish. We used a gynogenesis-b
4E-BPs require non-canonical 4E-binding motifs and a lateral surface of eIF4E to repress translation
Publikováno v:
Nature Communications
eIF4E-binding proteins (4E-BPs) are a widespread class of translational regulators that share a canonical (C) eIF4E-binding motif (4E-BM) with eIF4G. Consequently, 4E-BPs compete with eIF4G for binding to the dorsal surface on eIF4E to inhibit transl
Autor:
Francisco, Pelegri, Marcus P S, Dekens, Stefan, Schulte-Merker, Hans-Martin, Maischein, Catrin, Weiler, Christiane, Nüsslein-Volhard
Publikováno v:
Developmental dynamics : an official publication of the American Association of Anatomists. 231(2)
In animal species, early developmental processes are driven by maternally derived factors. Here, we describe a forward genetics approach to identify recessive mutations in genes encoding such maternal factors in the zebrafish. We used a gynogenesis-b